[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579080":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":31,"responsibleParty":147,"collaborators":12,"id":149,"slug":150,"hasResults":151,"nctId":152,"briefTitle":153,"officialTitle":153,"acronym":154,"eligibilityCriteria":155,"healthyVolunteers":151,"sex":156,"minAge":157,"maxAge":12,"enrollmentInfo":158,"targetDuration":12,"studyType":161,"phases":162,"briefSummary":164,"conditions":165,"keywords":167,"overallStatus":34,"whyStopped":12,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":180},{"fullName":5,"class":6},"University Hospital, Brest","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","NO_INTERVENTION","The control arm will consist of patients with hypoxemic respiratory distress treated by high flow oxygen therapy according to standard procedures.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"interventional","EXPERIMENTAL","The interventional arm will consist of patients with hypoxemic respiratory distress treted by high flow oxygen therapy with adjustement of ventilatory parametres based on lung volume measurements.",[18],"Drug: high flow oxygen therapy rate adjusted of lung volumes measured",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"DRUG","high flow oxygen therapy rate adjusted of lung volumes measured","Use of a technique based on non-contact measurement of lung volumes by depth camera in order to optimise the use of hihg flow oxygen therapy, with adaptation of the flow rate.",[14],[26],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Laetitia BODENES, Dr","CONTACT","+33 2 30 33 76 78","laetitia.bodenes@chu-brest.fr",[32,48,63,77,91,105,119,133],{"facility":33,"status":34,"city":35,"state":12,"zip":12,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Brest, University Hospital","RECRUITING","Brest","France","FR",{"type":39,"coordinates":40},"Point",[41,42],-4.48628,48.39029,{"lat":42,"lon":41},[45],{"name":46,"role":28,"phone":29,"phoneExt":47,"email":30},"Laetitia Bodenes, Dr","+33",{"facility":49,"status":50,"city":51,"state":12,"zip":52,"country":36,"countryCode":37,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"AP-HP - Hôpital Louis Mourier","NOT_YET_RECRUITING","Colombes","92700",{"type":39,"coordinates":54},[55,56],2.25404,48.91882,{"lat":56,"lon":55},[59],{"name":60,"role":28,"phone":61,"phoneExt":12,"email":62},"Jean-Damien RICARD, Prof","+33 1 47 60 61 91","jean-damien.ricard@aphp.fr",{"facility":64,"status":50,"city":65,"state":12,"zip":66,"country":36,"countryCode":37,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"AP-HP - Hôpital Henri Mondor","Créteil","94010",{"type":39,"coordinates":68},[69,70],2.46569,48.79266,{"lat":70,"lon":69},[73],{"name":74,"role":28,"phone":75,"phoneExt":12,"email":76},"Armand MEKONTSO-DESSAP, Prof","+33 1 49 81 23 91","armand.dessap@aphp.fr",{"facility":78,"status":50,"city":79,"state":12,"zip":80,"country":36,"countryCode":37,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"CH Morlaix","Morlaix","29672",{"type":39,"coordinates":82},[83,84],-3.82792,48.57784,{"lat":84,"lon":83},[87],{"name":88,"role":28,"phone":89,"phoneExt":12,"email":90},"Pierre-Yves EGRETEAU, Dr","+33 2 98 62 60 95","pyegreteau@ch-morlaix.fr",{"facility":92,"status":50,"city":93,"state":12,"zip":94,"country":36,"countryCode":37,"cosmosGeoPoint":95,"geoPoint":99,"contacts":100},"CHR Orléans","Orléans","45067",{"type":39,"coordinates":96},[97,98],1.90407,47.90248,{"lat":98,"lon":97},[101],{"name":102,"role":28,"phone":103,"phoneExt":12,"email":104},"Mai-Anh NAY, Dr","+33 2 38 57 52 53","mai-anh.nay@chr-orleans.fr",{"facility":106,"status":50,"city":107,"state":12,"zip":108,"country":36,"countryCode":37,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"CH Poitiers","Poitiers","86000",{"type":39,"coordinates":110},[111,112],0.34348,46.58261,{"lat":112,"lon":111},[115],{"name":116,"role":28,"phone":117,"phoneExt":12,"email":118},"Jean-Pierre FRAT, Dr","+33 5 49 44 44 44","Jean-pierre.frat@chu-poitiers.fr",{"facility":120,"status":50,"city":121,"state":12,"zip":122,"country":36,"countryCode":37,"cosmosGeoPoint":123,"geoPoint":127,"contacts":128},"CHU Rennes","Rennes","35033",{"type":39,"coordinates":124},[125,126],-1.67431,48.11109,{"lat":126,"lon":125},[129],{"name":130,"role":28,"phone":131,"phoneExt":12,"email":132},"Nicolas TERZI, Dr","+33 4 76 76 71 09","nicolas.terzi@chu-rennes.fr",{"facility":134,"status":50,"city":135,"state":12,"zip":136,"country":36,"countryCode":37,"cosmosGeoPoint":137,"geoPoint":141,"contacts":142},"CHU Tours","Tours","37044",{"type":39,"coordinates":138},[139,140],0.70398,47.39484,{"lat":140,"lon":139},[143],{"name":144,"role":28,"phone":145,"phoneExt":12,"email":146},"Pierre-François DEQUIN, Dr","+33 2 47 47 38 55","pierre-francois.dequin@univ-tours.fr",{"type":148,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100579080","phase-3-optimisation-of-high-flow-oxygen-therapy-settings-during-hypoxaemic-respiratory-distress-based-on-non-contact-measurement-of-lung-volumes-by-depth-camera-100579080",false,"NCT06819644","Optimisation of High Flow Oxygen Therapy Settings During Hypoxaemic Respiratory Distress Based on Non-contact Measurement of Lung Volumes by Depth Camera","DiStok","Inclusion Criteria:\n\n* Patients with hypoxemic respiratory distress define by the following 4 criteria:\n* Respiratory rate ≥ 25 breaths per minutes\n* A ratio of the partial pressure of arterial oxygen (PaO2) to the FiO2 ≤ 300 mmHg while the patient is breathing oxygen at a flow rate of 10 liters per minutes or more\n* A partial pressure of arterial carbon dioxide (PaCO2) not higher than 45 mmHg\n* An absence of clinical history of underlying chronic respiratory failure\n\nExclusion Criteria:\n\n* A do-not-intubate order\n* Pregnant or lactating woman\n* Cardiogenic pulmonary edema\n* Exacerbation of asthma\n* Hemodynamic instability with use of vasopressor at significant dose (norepinephrine \\> 0.5 mg\u002Fh)\n* A Glasgow Coma Scale of 12 points of less\n* Contraindications to non-invasive ventilation\n* Urgent need for endotracheal intubation\n* High flow oxygen therapy started within 48 hours before inclusion\n* Patient under legal protection or deprived of liberty","ALL","18 Years",{"count":159,"type":160},406,"ESTIMATED","INTERVENTIONAL",[163],"PHASE3","The goal of this clinical trial is to validate the interest of a strategy adjusting the flow rate delivered under high-flow oxygen (HFO) therapy according to the lung volumes measured by a new technique, in intensive care patients with hypoxemic respiratory distress (HRD).\n\nThe main question it aims to answer is:\n\n\"The use of a technique of measurement of lung pulmonary with adjustement to the flow rate can make it possible to limite intubation in patients with HRD in intensive care?\" The participants will be the patients admitted in intensive care for HRD with the need for treatment with HFO.\n\nThis participants will be randomized in :\n\n* the arm control: treated by high flow oxygen therapy according to standard procedures.\n* or in the experimental arm : treated by high flow oxygen therapy with adjustement of ventilatory parametres based on lung volume measurements, obtained by the depth camera.",[166],"Hypoxemic Respiratory Failure",[168,169,170],"flow oxygen","lung volume","depth camera","2026-06-25",{"date":173,"type":174},"2026-06-29","ACTUAL",{"date":176,"type":174},"2026-04-08",{"date":178,"type":160},"2030-10",{"name":5,"class":6},8]