[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611843":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":20,"responsibleParty":30,"collaborators":20,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":20,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":40,"maxAge":20,"enrollmentInfo":41,"targetDuration":20,"studyType":44,"phases":45,"briefSummary":47,"conditions":48,"keywords":50,"overallStatus":54,"whyStopped":20,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":20},{"fullName":5,"class":6},"Ottawa Heart Institute Research Corporation","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Recurrent pericarditis","EXPERIMENTAL","This is a single arm study. Participants enrolled will complete blood and imaging tests.",[13],"Diagnostic Test: 18F-FDG PET\u002FCT",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","18F-FDG PET\u002FCT","The participants will under an 18F-FDG PET\u002FCT with CTA.",[9],null,[22,27],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Kevin Boczar, MD","CONTACT","613-696-7083","KBoczar@ottawaheart.ca",{"name":28,"role":24,"phone":20,"phoneExt":20,"email":29},"Poppy MacPhee, RN","pmacphee@ottawaheart.ca",{"type":31,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100611843","phase-3-pericardial-imaging-study-100611843",false,"NCT07245849","Pericardial Imaging Study","Identifying Clinical, Serum, and Imaging Based Biomarkers Associated With High-Risk Phenotypes for Recurrent Pericarditis: A Prospective Cohort Study","Inclusion Criteria:\n\n1. History of recurrent pericarditis\\* (i.e. presentation of at lease 2nd episode of acute pericarditis).\n2. Age \\>\u002F= 18 years\n3. Given informed consent\n\n   * standard definitions will be used to define an episode of pericarditis. Pericarditis will be diagnosed by using available published criteria, which includes typical pericardial chest pain, pericardial friction rubs, widespread ST segment elevation or PR-segment depression that was not previously reported and new or worsening pericardial effusion on echocardiography. A clinical diagnosis of acute pericarditis will be made when at least 3 of these criteria are present.\n\nExclusion Criteria:\n\n1. severe valve disease requiring intervention\n2. claustrophobia that precludes FDG\u002FPET or CMR imaging\n3. pregnancy (all women of child bearing potential will have a negative BHCG test)\n4. breastfeeding\n5. glomerular filtration rate (GFR) \\\u003C50 m\u002Fmin\u002F1.72m2","ALL","18 Years",{"count":42,"type":43},44,"ESTIMATED","INTERVENTIONAL",[46],"PHASE3","The pericardium is a thin, double-layered sac around the heart that helps reduce friction as the heart moves. When this sac gets inflamed, it is called pericarditis, which can cause serious health problems and even be life-threatening. Pericarditis often comes back after the first episode. About 10-30% of people will have it again, and half of those will have it multiple times. Although there are treatments available, they are costly and not often used because we can't predict who best to use them on. Finding a way to predict which patients would benefit from these treatments could help reduce the burden on patients and the healthcare system.\n\nThis study will use a test called an 18F-FDG PET\u002FCT with CTA Scan (18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) with computer tomography angiography (CTA)) to measure inflammation in the pericardium.\n\nThe purpose of the study is to create easy-to-use tools for doctors to identify people at high risk of pericarditis coming back, so they can get advanced treatment early. This study will help fill knowledge gaps about key predictors like clinical signs, blood tests, and imaging results.",[49],"Pericarditis",[51,52,53],"PET","pericarditis","FDG","NOT_YET_RECRUITING","2026-04-29",{"date":57,"type":58},"2026-05-01","ACTUAL",{"date":60,"type":43},"2026-12",{"date":62,"type":43},"2027-07",{"name":5,"class":6}]