[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100448486":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":38,"locations":49,"responsibleParty":69,"collaborators":43,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":43,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":43,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":43,"overallStatus":52,"whyStopped":43,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Balgrist University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dexamethasone group","ACTIVE_COMPARATOR","The patients in the dexamethasone group will receive 12mg dexamethasone (Fortecortin ®) intravenously 15-60 minutes prior to surgery while in general anasthesia as well as 12mg dexamethasone intravenously (Fortecortin®) on the first postoperative day at approx. 8.00a.m. by the investigators.",[13],"Drug: Dexamethasone 4 Mg\u002FmL Injectable Solution",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo\u002F Control group","PLACEBO_COMPARATOR","The patients will not receive any additional drugs preoperatively. 3ml of a 0.9% NaCl Solution (NaCl B. Braun Inf Lös 0.9 % 250ml Ecoflac plus®) will be administered at approx. 8.00 a.m. on the first postoperative day by the investigators.",[19],"Drug: NaCl 0.9%",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Dexamethasone 4 Mg\u002FmL Injectable Solution","s. arm\u002Fgroup description",[9],[27],"Fortecortin Inject (Merck (Switzerland))",{"type":22,"name":29,"description":24,"armGroupLabels":30,"otherNames":31},"NaCl 0.9%",[15],[32],"NaCL Braun (B Braun medical)",[34],{"name":35,"affiliation":36,"role":37},"Patrick Zingg, MD","Study Principal Investigator","PRINCIPAL_INVESTIGATOR",[39,45],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Dominik Kaiser, MD","CONTACT","+41443865764",null,"dominik.kaiser@balgrist.ch",{"name":46,"role":41,"phone":47,"phoneExt":43,"email":48},"Sabrina Catanzaro, study nurse","+41443867370","sabrina.catanzaro@balgrist.ch",[50],{"facility":51,"status":52,"city":53,"state":43,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Uniklinik Balgrist","RECRUITING","Zurich","8008","Switzerland","CH",{"type":58,"coordinates":59},"Point",[60,61],8.55,47.36667,{"lat":61,"lon":60},[64,66],{"name":65,"role":41,"phone":42,"phoneExt":43,"email":44},"Dominik Kaiser",{"name":67,"role":41,"phone":43,"phoneExt":43,"email":68},"Patrickt Zingg","patrick.zingg@balgrist.ch",{"type":70,"investigatorFullName":43,"investigatorTitle":43,"investigatorAffiliation":43,"oldNameTitle":43,"oldOrganization":43},"SPONSOR","100448486","phase-3-perioperative-dexamethasone-reduces-postoperative-pain-and-nausea-after-periacetabular-osteotomy-100448486",false,"NCT05120076","Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Periacetabular Osteotomy","Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Periacetabular Osteotomy- a Double-blinded Placebo Controlled RCT","Inclusion Criteria:\n\n* Age ≥ 18 years\n* General anasthesia\n* Elective periacetabular osteotomy for any reason\n* Written informed consent as documented by signature (Appendix Informed Consent Form)\n* Competent German language skills\n\nExclusion Criteria:\n\n* Chronic pain patient, chronic lower back pain\n* Steroid or immunosuppressive drugs used within 6 months of surgery\n* Renal failure, hepatic failure\n* Relevant allergies\n* Pregnancy\u002F Breast feeding\n* Contraindications for Fortecortin treatment according to Swissmedic\n* Previous enrollment into the current study\n* Participation in another study with investigational drug within the 30 days preceding and during the present study\n* Known or suspected non-compliance, drug or alcohol abuse Illness according to \"Warnings and Precautions of Dexamethasone and NaCl\"",true,"ALL","18 Years","99 Years",{"count":83,"type":84},60,"ESTIMATED","INTERVENTIONAL",[87],"PHASE3","The purpose of this study is to assess the effect of Dexamethasone on postoperative pain and nausea after periacetabular osteotomy.",[90,91,92],"Pain","Postoperative Nausea","Amount of Postoperative Opioid Use in Milligrams","2024-08-09",{"date":95,"type":96},"2024-08-12","ACTUAL",{"date":98,"type":96},"2021-07-16",{"date":100,"type":84},"2024-08-31",{"name":5,"class":6},1]