[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609022":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":25,"locations":24,"responsibleParty":31,"collaborators":24,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":38,"acronym":24,"eligibilityCriteria":39,"healthyVolunteers":35,"sex":40,"minAge":41,"maxAge":24,"enrollmentInfo":42,"targetDuration":24,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":52,"overallStatus":55,"whyStopped":24,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":24},{"fullName":5,"class":6},"Ohio State University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"3 day prophylaxis","EXPERIMENTAL","3 days of perioperative culture directed antibiotic prophylaxis will be prescribed to this group (to start 1 day prior to surgery). macrobid if preoperative culture is negative",[13],"Drug: antibiotic prophylaxis",{"label":15,"type":6,"description":16,"interventionNames":17},"7 day prophylaxis","7 days of perioperative culture directed antibiotic prophylaxis will be prescribed to this group (to start 4 day prior to surgery). macrobid if preoperative culture is negative",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","antibiotic prophylaxis","we will compare varying durations of antibiotic prophylaxis prior to prostate enucleation surgery",[9,15],null,[26],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},"Matthew Lee, MD","CONTACT","614-293-8155","matthew.lee@osumc.edu",{"type":32,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100609022","phase-3-randomized-controlled-trial-of-different-antibiotic-duration-prior-to-prostate-enucleation-surgery-100609022",false,"NCT07209150","Randomized Controlled Trial of Different Antibiotic Duration Prior to Prostate Enucleation Surgery","Randomized Controlled Trial of 3 vs 7 Days for Perioperative Antibiotic Prophylaxis for Patients With an Indwelling Catheter Prior to Holmium Laser Enucleation of the Prostate","Inclusion Criteria:\n\n* 1\\. Candidate for HoLEP surgery 2. Must be 18 years or older. 3. The patient must be able to understand and willing to provide informed consent as described in this study protocol.\n\nExclusion Criteria:\n\n* 1\\. Under the age of 18 2. Refuse to provide informed consent 3. Anticipated need for perineal urethrostomy 4. History of multi-drug resistant organism on urine culture that is not susceptible to any oral agents","MALE","18 Years",{"count":43,"type":44},250,"ESTIMATED","INTERVENTIONAL",[47],"PHASE3","To compare the risk of infectious complications (UTI, pyelonephritis, sepsis, hospital admission, ED visits) for patients with an indwelling urinary catheter (urethral or suprapubic) or CIC receiving 3 or 7 days of peri-operative antibiotic prophylaxis at time of Holmium Laser Enucleation of the Prostate",[50,51],"BPH With Urinary Obstruction","Antibiotic Prophylaxis",[53,54,21],"bph","urinary retention","NOT_YET_RECRUITING","2025-09-30",{"date":58,"type":59},"2025-10-06","ACTUAL",{"date":61,"type":44},"2026-01-01",{"date":63,"type":44},"2028-07-15",{"name":5,"class":6}]