[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625777":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":37,"centralContacts":41,"locations":46,"responsibleParty":71,"collaborators":30,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":75,"sex":81,"minAge":82,"maxAge":30,"enrollmentInfo":83,"targetDuration":30,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":96,"overallStatus":48,"whyStopped":30,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Brigham and Women's Hospital","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Pre-implementation historical baseline - Standard care prior to study intervention","ACTIVE_COMPARATOR","Standard care prior to study intervention",[13],"Drug: pre-implementation baseline including opioid",{"label":15,"type":10,"description":16,"interventionNames":17},"Post-implementation ROPES with multimodal analgesia pathway alone","Educated on post-op pain management, multimodal analgesia scripts given but no pre-emptive opioid script (to obtain opioid after discharge patient must call phone line to request).",[18],"Drug: multimodal analgesia pathway without up-front small opioid prescription",{"label":20,"type":10,"description":21,"interventionNames":22},"Post-implementation ROPES with multimodal analgesia pathway and up-front small opioid prescription","Educated on post-op pain management, multimodal analgesia scripts given and additionally given pre-emptive standard opioid script.",[23],"Drug: multimodal analgesia pathway with up-front small opioid prescription",[25,31,34],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DRUG","multimodal analgesia pathway with up-front small opioid prescription","multimodal analgesia pathway including an up-front small opioid prescription",[20],null,{"type":26,"name":32,"description":32,"armGroupLabels":33,"otherNames":30},"multimodal analgesia pathway without up-front small opioid prescription",[15],{"type":26,"name":35,"description":35,"armGroupLabels":36,"otherNames":30},"pre-implementation baseline including opioid",[9],[38],{"name":39,"affiliation":5,"role":40},"Timothy Clinton, MD","PRINCIPAL_INVESTIGATOR",[42],{"name":39,"role":43,"phone":44,"phoneExt":30,"email":45},"CONTACT","617-732-6384","tclinton1@bwh.harvard.edu",[47,63],{"facility":5,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-71.05977,42.35843,{"lat":58,"lon":57},[61],{"name":62,"role":43,"phone":44,"phoneExt":30,"email":45},"Timothy Clinton",{"facility":64,"status":48,"city":49,"state":50,"zip":65,"country":52,"countryCode":53,"cosmosGeoPoint":66,"geoPoint":68,"contacts":69},"Brigham and Women's Faulkner Hospital","02130",{"type":55,"coordinates":67},[57,58],{"lat":58,"lon":57},[70],{"name":62,"role":43,"phone":44,"phoneExt":30,"email":45},{"type":40,"investigatorFullName":62,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Associate Surgeon","100625777","phase-3-robotic-opioid-free-prostatectomy-enhanced-strategy-ropes-100625777",false,"NCT07427043","Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)","Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES): Implementation of an Opioid-free Multimodal Analgesia Discharge Pathway","ROPES","Inclusion Criteria:\n\n* Men ≥45 years old\n* Undergoing Robotic Assisted Laparoscopic Prostatectomy (RALP) at BWH or BWFH\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Chronic kidney disease (baseline Cr \\>1.3)\n* NSAID contraindication\u002Fallergy\n* Regular opioid use or substance abuse prior to surgery\n* Inability to provide their own consent\n* Deviation from standard surgical practice for RALP (e.g. major complication requiring operative intervention that would result in patient no longer being considered a routine case)","MALE","45 Years",{"count":84,"type":85},300,"ESTIMATED","INTERVENTIONAL",[88],"PHASE3","This prospective, interventional, open-label, phase 3 randomized study evaluates a multimodal analgesia discharge pathway to reduce automatic opioid prescribing following routine robotic-assisted laparoscopic prostatectomy (RALP). Patients are counseled on post-operative pain management and then may opt into or out of the study with randomization to discharge prescriptions including (A) multimodal plan with additional automatic opioid prescription or (B) multimodal plan alone and instruction to call phone line to request opioid prescription if pain management is insufficient. Additionally, a cohort of historical controls prior to implementation of the study is also prospectively assessed as a pre-study baseline. The primary outcome is postoperative opioid consumption. Secondary outcomes include bowel function recovery, unplanned care encounters including emergency department visits or postoperative phone calls, and same-day discharge rates.",[91,92,93,94,95],"Opioid Consumption, Postoperative","Multimodal Analgesia","Robotic Assisted Laparoscopic Surgery","Robotic Assisted Laparoscopic Radical Prostatectomy","Prostate Cancer",[92,94,97,98,93],"Postoperative Opioid Consumption","Localized Prostate Cancer","2026-05-20",{"date":101,"type":102},"2026-05-22","ACTUAL",{"date":104,"type":102},"2026-03-01",{"date":106,"type":85},"2027-04-30",{"name":5,"class":6},2]