[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598813":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":30,"responsibleParty":47,"collaborators":20,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":20,"enrollmentInfo":59,"targetDuration":20,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":70,"overallStatus":32,"whyStopped":20,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Observational Cohort","EXPERIMENTAL","Patients with singleton vertex pregnancies in active labor (spontaneous or after induction of labor), with a cervical dilatation between 1 and 7cm who are requesting neuraxial labor analgesia, Age =\\>18 yrs",[13],"Drug: Ropivacaine + Fentanyl",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Ropivacaine + Fentanyl","A standard epidural admixture - 0.1% Ropivacaine + 2 mcg\u002Fml fentanyl - will be used.",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Alexander Butwick, MBBS, FRCA, MS","PRINCIPAL_INVESTIGATOR",[26],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},"CONTACT","415-514-3757","alexander.butwick@ucsf.edu",[31],{"facility":5,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","San Francisco","California","94158","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-122.41942,37.77493,{"lat":42,"lon":41},[45],{"name":46,"role":27,"phone":28,"phoneExt":20,"email":29},"Alexander Butwick",{"type":48,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100598813","phase-3-ropivacaine-and-fentanyl-for-labor-epidural-initiation-100598813",false,"NCT07076368","Ropivacaine and Fentanyl for Labor Epidural Initiation","Determination of the 90% Effective Volume (ED90) of Epidural 0.1% Ropivacaine and Fentanyl for Labor Analgesia Initiation in Patients Receiving a Dural-Puncture Epidural Technique","EV90_DPE","Inclusion Criteria:\n\n* Patients with singleton vertex pregnancies in active labor (latent or spontaneous labor or after induction of labor)\n* Cervical dilatation between 2 and 7 cm\n* Requesting neuraxial labor analgesia\n* Age 18 or older\n\nExclusion Criteria:\n\n* Significant obstetric disease (e.g., pre-eclampsia, major cardiac disease)\n* Chronic pain or chronic opioid use\n* BMI ≥ 50\n* Multiple gestations\n* Allergy or anaphylaxis to local anesthetic\n* Fetal compromise or non-reassuring fetal trace\n* Age under 18\n* Inability to speak and understand English or Spanish","FEMALE","18 Years",{"count":60,"type":61},50,"ESTIMATED","INTERVENTIONAL",[64],"PHASE3","This study is being done to determine the most effective dose of medicine to use to initially provide effective pain relief within the first 30 minutes of receiving an epidural for pain labor during labor. The study team will also study any side effects related to the epidural medication and patients' satisfaction with the quality of pain relief after receiving the epidural.",[67,68,69],"Pregnancy","Labor and Delivery","Labor Analgesia",[71,72,73,74],"epidural","labor analgesia","pregnancy","obstetric anesthesia","2026-01-23",{"date":77,"type":78},"2026-01-27","ACTUAL",{"date":80,"type":78},"2025-10-24",{"date":82,"type":61},"2026-07-31",{"name":5,"class":6},1]