[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575639":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":28,"locations":39,"responsibleParty":63,"collaborators":65,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":11,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":89,"overallStatus":94,"whyStopped":11,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm A : A custom-molded lumbar-sacral orthosis","EXPERIMENTAL",null,[13,14],"Device: Custom-molded lumbar-sacral orthosis","Other: Usual Care",{"label":16,"type":17,"description":11,"interventionNames":11},"Arm B : a standardized prescription of 20 outpatient physiotherapy sessions","NO_INTERVENTION",[19,24],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"DEVICE","Custom-molded lumbar-sacral orthosis","A custom-molded lumbar-sacral orthosis made according to the Vésinet method associated with measures designed to enhance adherence based on goal-setting techniques (i.e. personalized advice, self-determination of the wearing time, hotline) techniques and monitoring of adherence using a temperature sensor chip to provide feedbacks to participants on the wearing time at follow-up visits, and usual care (i.e. a standardized prescription of 20 outpatient physiotherapy sessions including active self-correction, spinal muscle strengthening, spine and lower limb stretching and learning of home-based exercises).",[9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"Usual Care","Usual care consisting in a standardized prescription of 20 outpatient physiotherapy sessions including active self-correction, spinal muscle strengthening, spine and lower limb stretching and learning of home-based exercises",[9],[29,35],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Christelle NGUYEN, MD, PhD","CONTACT","01 58 41 29 95","+33","christelle.nguyen2@aphp.fr",{"name":36,"role":31,"phone":37,"phoneExt":33,"email":38},"Valérie PLENCE, Msc","01 58 41 11 78","valerie.plence-fauroux@aphp.fr",[40],{"facility":41,"status":11,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Assistance Publique - Hôpitaux de Paris, Service de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis, Hôpital Cochin","Paris","Île-de-France Region","75014","France","FR",{"type":48,"coordinates":49},"Point",[50,51],2.3488,48.85341,{"lat":51,"lon":50},[54,57,61],{"name":55,"role":31,"phone":56,"phoneExt":33,"email":34},"Christelle Nguyen, MD, PhD","01 58 41 29 45",{"name":58,"role":31,"phone":59,"phoneExt":33,"email":60},"François Rannou, MD, PhD","01 58 41 25 35","françois.rannou@aphp.fr",{"name":30,"role":62,"phone":11,"phoneExt":11,"email":11},"PRINCIPAL_INVESTIGATOR",{"type":64,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[66],{"name":67,"class":6},"URC-CIC Paris Descartes Necker Cochin","100575639","phase-3-spinal-bracing-in-adults-with-painful-degenerative-scoliosis-a-randomized-controlled-open-trial-100575639",false,"NCT06774898","Spinal Bracing in Adults With Painful Degenerative Scoliosis: a Randomized Controlled Open Trial","BRASCO","Inclusion Criteria:\n\n* Adults aged 40 to 75 years,\n* Degenerative thoracolumbar or lumbar scoliosis with Cobb angle for the largest curve greater than 20°on EOS® full-spine X-ray less than 1 year (this can be a de-novo scoliosis, or a degenerative scoliosis that appears on an idiopathic scoliosis), and\n* Low back pain with a duration more than 3 months\n* Low back pain with an intensity greater than 40 of 100 points on a self-administered numeric rating scale.\n* Patient able to give written informed consent prior to participation in the study Affiliation with a mode of social security (profit or being entitled).\n\nExclusion Criteria:\n\n* Spinal deformity secondary to a specific condition (e.g. fracture, infection, tumour, inflammatory rheumatic disease, neuromuscular disorder, genetic disorder),\n* History of spine surgery,\n* Morphotype and\u002For conditions making spinal bracing technically impossible (e.g. obesity, severe clinical sagittal and\u002For coronal malalignment, recent abdominal surgery etc)\n* Inability to speak and\u002For read French language,\n* Inability or refusal to wear a custom-molded lumbar-sacral orthosis,\n* Patients already wearing a custom-molded lumbar-sacral orthosis,\n* Cognitive disorders,\n* People under tutorship or curatorship,\n* Protected adults, and\n* Patients on AME (state medical aid),\n* Pregnant or breastfeeding women","ALL","40 Years","75 Years",{"count":79,"type":80},130,"ESTIMATED","INTERVENTIONAL",[83],"PHASE3","The purpose of this study is to compare the efficacy on low back pain intensity at 6 months after randomization of a custom-molded lumbar-sacral orthosis as an add-on therapy to usual care in people with painful adult degenerative scoliosis.",[86,87,88],"Degenerative Scoliosis","Scoliosis Idiopathic","Thoracolumbar Scoliosis",[90,91,92,93],"Scoliosis","Low back pain","Spine","Bracing","NOT_YET_RECRUITING","2026-04-27",{"date":97,"type":98},"2026-05-01","ACTUAL",{"date":100,"type":80},"2026-09",{"date":102,"type":80},"2030-09",{"name":5,"class":6},1]