[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100339727":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":34,"locations":35,"responsibleParty":56,"collaborators":58,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":30,"officialTitle":69,"acronym":34,"eligibilityCriteria":70,"healthyVolunteers":67,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":34,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":38,"whyStopped":34,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Women's Hospital School Of Medicine Zhejiang University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"chemotherapy","ACTIVE_COMPARATOR","Methotrexate 0.4mg\u002Fkg·d, im ,\\*5d started at the first day of cycle, two weeks a cycle",[13],"Drug: Methotrexate",{"label":15,"type":16,"description":17,"interventionNames":18},"study group","EXPERIMENTAL","hysteroscopic repeat curettage",[19],"Procedure: hysteroscopic repeat curettage",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Methotrexate","single-agent 5-day methotrexate, two weeks a cycle",[9],[27],"Methotrexate chemotherapy",{"type":29,"name":17,"description":30,"armGroupLabels":31,"otherNames":32},"PROCEDURE","Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia",[15],[33],"complete curettage",null,[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Weiguo Lv","RECRUITING","Hangzhou","Zhejiang","310006","China","CN",{"type":45,"coordinates":46},"Point",[47,48],120.16142,30.29365,{"lat":48,"lon":47},[51],{"name":52,"role":53,"phone":54,"phoneExt":34,"email":55},"Weiguo Lv, Doctor","CONTACT","13588193832","13588193832@163.com",{"type":57,"investigatorFullName":34,"investigatorTitle":34,"investigatorAffiliation":34,"oldNameTitle":34,"oldOrganization":34},"SPONSOR",[59,61,63],{"name":60,"class":6},"Sun Yat-sen University",{"name":62,"class":6},"Huazhong University of Science and Technology",{"name":64,"class":6},"Qilu Hospital of Shandong University","100339727","phase-3-study-of-hysteroscopic-repeat-curettage-as-the-first-line-treatment-in-low-risk-postmolar-gestational-trophoblastic-neoplasia-100339727",false,"NCT03703271","A Non-Inferiority Prospective Randomized Multicenter Clinical Control Study of Hysteroscopic Repeat Curettage as the Primal Management of Low-risk Postmolar Gestational Trophoblastic Neoplasia","Inclusion Criteria:\n\n* low-risk postmolar gestational trophoblastic neoplasia (GTN)\n* World Health Organization(WHO) risk score≤4\n* Age≤60 years; female, Chinese women\n* Initial treatment\n* Performance status: Karnofsky score≥60\n* Laboratory tests: WBC≥3.5×10(9)\u002FL, ANC≥1.5×10(9)\u002FL, PLT≥80×10(9)\u002FL, serum bilirubin≤ 1.5 times the upper limit of normal, transaminase≤ 1.5 times the upper limit of normal,blood urea nitrogen, Cr≤ normal\n* Provide written informed consent.\n\nExclusion Criteria:\n\n* Patients with unconfirmed diagnosis of GTN\n* Patients with placental-site trophoblastic tumor (PSTT) or epithelioid trophoblastic tumor (ETT)\n* WHO risk score ≥5分\n* The diameter of a single metastatic lesion in the lung was ≥2cm\n* The number of lung CT metastases was≥ 5\n* With severe or uncontrolled internal disease, unable to receive chemotherapy\n* Concurrently participating in other clinical trials\n* Unable or unwilling to sign informed consents\n* Unable or unwilling to abide by protocol","FEMALE","12 Years","60 Years",{"count":75,"type":76},70,"ESTIMATED","INTERVENTIONAL",[79],"PHASE3","Study of hysteroscopic repeat curettage as the first-line treatment in low-risk postmolar gestational trophoblastic neoplasia compared with the MTX single drug chemotherapy",[82],"Gestational Trophoblastic Neoplasia",[84,82,85,86,87],"postmolar","hysteroscopic","repeat curettage","methotrexate","2026-06-28",{"date":90,"type":91},"2026-07-01","ACTUAL",{"date":93,"type":91},"2019-03-01",{"date":95,"type":76},"2026-12-31",{"name":5,"class":6},1]