[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640322":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":44,"centralContacts":49,"locations":55,"responsibleParty":379,"collaborators":31,"id":381,"slug":382,"hasResults":383,"nctId":384,"briefTitle":385,"officialTitle":386,"acronym":31,"eligibilityCriteria":387,"healthyVolunteers":383,"sex":388,"minAge":389,"maxAge":31,"enrollmentInfo":390,"targetDuration":31,"studyType":393,"phases":394,"briefSummary":396,"conditions":397,"keywords":399,"overallStatus":401,"whyStopped":31,"lastUpdateSubmitDate":402,"lastUpdatePostDateStruct":403,"startDateStruct":406,"completionDateStruct":408,"leadSponsor":410,"locationsCount":411},{"fullName":5,"class":6},"R-Pharm","INDUSTRY",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Goflikicept","EXPERIMENTAL","Goflikicept is administered at a dose of 320 mg intravenously (IV) infusion on Day 0, followed by 160 mg subcutaneously (SC) on Day 14 and subsequently 160 mg SC every 2 weeks",[13],"Biological: Goflikicept",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Placebo is administered at a dose of 320 mg intravenously (IV) infusion on Day 0, followed by 160 mg subcutaneously (SC) on Day 14 and subsequently 160 mg SC every 2 weeks",[19],"Drug: Placebo",{"label":21,"type":22,"description":23,"interventionNames":24},"Olokizumab","OTHER","Participants who do not respond to treatment with Goflikicept (including those switched from placebo) are transitioned to second-line therapy with Olokizumab. Olokizumab is administered at 128 mg intravenously at the initiation visit, followed by response assessment at Day 7. Participants who respond to treatment continue Olokizumab at a dose of 64 mg subcutaneously every 2 weeks during the treatment period",[25],"Biological: Olokizumab",[27,32,39],{"type":28,"name":15,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","0.9% Sodium Chloride solution for Injection",[15],null,{"type":33,"name":9,"description":34,"armGroupLabels":35,"otherNames":36},"BIOLOGICAL","solution for subcutaneous injection and intravenous infusion, 40 mg\u002FmL",[9],[37,38],"RPH-104","Arcerix",{"type":33,"name":21,"description":40,"armGroupLabels":41,"otherNames":42},"solution for subcutaneous injection and intravenous infusion, 160 mg\u002FmL",[21],[43],"Artlegia",[45],{"name":46,"affiliation":47,"role":48},"Mikhail Samsonov","R-Pharm International, LLC","STUDY_DIRECTOR",[50],{"name":51,"role":52,"phone":53,"phoneExt":31,"email":54},"Olga Sankova","CONTACT","+7 (915) 486-45-25","sankova@rpharm.ru",[56,73,87,101,115,126,137,148,159,170,181,195,206,220,234,248,262,273,284,295,309,323,337,351,365],{"facility":57,"status":31,"city":58,"state":31,"zip":59,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"Republic Clinical and Diagnostic Center of the Ministry of Health of the Udmurt Republic","Izhevsk","426009","Russia","RU",{"type":63,"coordinates":64},"Point",[65,66],53.19862,56.85225,{"lat":66,"lon":65},[69],{"name":70,"role":52,"phone":71,"phoneExt":31,"email":72},"Larisa Ivanova","(3412) 682600","loraivanova7@mail.ru",{"facility":74,"status":31,"city":75,"state":31,"zip":76,"country":60,"countryCode":61,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"\"Vashe Zdorovie\" Research Medical Complex, LLC","Kazan'","420097",{"type":63,"coordinates":78},[79,80],49.12214,55.78874,{"lat":80,"lon":79},[83],{"name":84,"role":52,"phone":85,"phoneExt":31,"email":86},"Svetlana Yakupova","8 (843) 537 93 93","YakupovaSP@mail.ru",{"facility":88,"status":31,"city":89,"state":31,"zip":90,"country":60,"countryCode":61,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Family Clinic No. 4, LLC","Korolyov","141060",{"type":63,"coordinates":92},[93,94],37.82556,55.91417,{"lat":94,"lon":93},[97],{"name":98,"role":52,"phone":99,"phoneExt":31,"email":100},"Nino Mosesova","+7 (495) 859-42-19","nino1999@mail.ru",{"facility":102,"status":31,"city":103,"state":31,"zip":104,"country":60,"countryCode":61,"cosmosGeoPoint":105,"geoPoint":109,"contacts":110},"Limited Liability Company \"OLLA-MED\"","Moscow","105554",{"type":63,"coordinates":106},[107,108],37.61781,55.75204,{"lat":108,"lon":107},[111],{"name":112,"role":52,"phone":113,"phoneExt":31,"email":114},"Daria Kusevich","+7 495 105 99 05","ctd@ollamed.ru",{"facility":116,"status":31,"city":103,"state":31,"zip":117,"country":60,"countryCode":61,"cosmosGeoPoint":118,"geoPoint":120,"contacts":121},"State Budgetary Healthcare Institution \"A.S. Loginov Moscow Clinical Scientific Center of the Moscow Department of Healthcare\"","111123",{"type":63,"coordinates":119},[107,108],{"lat":108,"lon":107},[122],{"name":123,"role":52,"phone":124,"phoneExt":31,"email":125},"Galina Lukina","+7 (495) 304-30-39","gvl3@yandex.ru",{"facility":127,"status":31,"city":103,"state":31,"zip":128,"country":60,"countryCode":61,"cosmosGeoPoint":129,"geoPoint":131,"contacts":132},"V.A. Nasonova Research Institute of Rheumatology (Federal State Budgetary Scientific Institution)","115522",{"type":63,"coordinates":130},[107,108],{"lat":108,"lon":107},[133],{"name":134,"role":52,"phone":135,"phoneExt":31,"email":136},"Anna Torgashina","+7 495 109-29-10","anna.torgashina@gmail.com",{"facility":138,"status":31,"city":103,"state":31,"zip":139,"country":60,"countryCode":61,"cosmosGeoPoint":140,"geoPoint":142,"contacts":143},"Limited Liability Company \"Firm ORIS\"","117321",{"type":63,"coordinates":141},[107,108],{"lat":108,"lon":107},[144],{"name":145,"role":52,"phone":146,"phoneExt":31,"email":147},"Elena Shchegoleva","+7 (495) 228-77-88","shchegoleva09@gmail.com",{"facility":149,"status":31,"city":103,"state":31,"zip":150,"country":60,"countryCode":61,"cosmosGeoPoint":151,"geoPoint":153,"contacts":154},"State Budgetary Healthcare Institution of the City of Moscow \"N.I. Pirogov City Clinical Hospital No. 1 of the Moscow Department of Healthcare\"","119049",{"type":63,"coordinates":152},[107,108],{"lat":108,"lon":107},[155],{"name":156,"role":52,"phone":157,"phoneExt":31,"email":158},"Alesya Klimenko","+7 (499) 764-50-02","aaklimenko@yandex.ru",{"facility":160,"status":31,"city":103,"state":31,"zip":161,"country":60,"countryCode":61,"cosmosGeoPoint":162,"geoPoint":164,"contacts":165},"I.M. Sechenov First Moscow State Medical University, University Clinical Hospital No. 3, E.M. Tareev Clinic of Rheumatology, Nephrology and Occupational Pathology","119435",{"type":63,"coordinates":163},[107,108],{"lat":108,"lon":107},[166],{"name":167,"role":52,"phone":168,"phoneExt":31,"email":169},"Sergey Moiseev","+7 (499) 450-88-89","avt420034@yahoo.com",{"facility":171,"status":31,"city":103,"state":31,"zip":172,"country":60,"countryCode":61,"cosmosGeoPoint":173,"geoPoint":175,"contacts":176},"Russian Gerontology Clinical Research Center (RGNC) of Pirogov Russian National Research Medical University","129226",{"type":63,"coordinates":174},[107,108],{"lat":108,"lon":107},[177],{"name":178,"role":52,"phone":179,"phoneExt":31,"email":180},"Alexey Meshkov","+7 (499) 187-29-96","alexeymeshkov@mail.ru",{"facility":182,"status":31,"city":183,"state":31,"zip":184,"country":60,"countryCode":61,"cosmosGeoPoint":185,"geoPoint":189,"contacts":190},"\"Zdorovaya Semya\" Medical Center","Novosibirsk","630099",{"type":63,"coordinates":186},[187,188],82.93175,55.02259,{"lat":188,"lon":187},[191],{"name":192,"role":52,"phone":193,"phoneExt":31,"email":194},"Elena Zonova","+7 (383) 383-00-68","Elena_zonova@list.ru",{"facility":196,"status":31,"city":183,"state":31,"zip":197,"country":60,"countryCode":61,"cosmosGeoPoint":198,"geoPoint":200,"contacts":201},"Federal Research Center \"Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences\"","630117",{"type":63,"coordinates":199},[187,188],{"lat":188,"lon":187},[202],{"name":203,"role":52,"phone":204,"phoneExt":31,"email":205},"Maxim Korolev","+7 (383) 333-64-09","kormax@bk.ru",{"facility":207,"status":31,"city":208,"state":31,"zip":209,"country":60,"countryCode":61,"cosmosGeoPoint":210,"geoPoint":214,"contacts":215},"Budgetary Healthcare Institution of the Omsk Region \"Regional Clinical Hospital\"","Omsk","644111",{"type":63,"coordinates":211},[212,213],73.36859,54.99244,{"lat":213,"lon":212},[216],{"name":217,"role":52,"phone":218,"phoneExt":31,"email":219},"Tatiana Kropotina","+7 (3812) 23-26-74","kropotina@list.ru",{"facility":221,"status":31,"city":222,"state":31,"zip":223,"country":60,"countryCode":61,"cosmosGeoPoint":224,"geoPoint":228,"contacts":229},"State Budgetary Healthcare Institution \"Orenburg Regional Clinical Hospital named after V.I. Voynov\"","Orenburg","460018",{"type":63,"coordinates":225},[226,227],55.09883,51.76712,{"lat":227,"lon":226},[230],{"name":231,"role":52,"phone":232,"phoneExt":31,"email":233},"Olga Bugrova","+7 (3532) 31-47-55","ov.bugrova@yandex.ru",{"facility":235,"status":31,"city":236,"state":31,"zip":237,"country":60,"countryCode":61,"cosmosGeoPoint":238,"geoPoint":242,"contacts":243},"State Budgetary Healthcare Institution \"V.A. Baranov Republican Hospital\"","Petrozavodsk","185000",{"type":63,"coordinates":239},[240,241],34.34691,61.78491,{"lat":241,"lon":240},[244],{"name":245,"role":52,"phone":246,"phoneExt":31,"email":247},"Irina Marusenko","+79004638475","Imarusenko@yandex.ru",{"facility":249,"status":31,"city":250,"state":31,"zip":251,"country":60,"countryCode":61,"cosmosGeoPoint":252,"geoPoint":256,"contacts":257},"Limited Liability Company \"Medical Technologies\"","Saint Petersburg","191025",{"type":63,"coordinates":253},[254,255],30.31413,59.93863,{"lat":255,"lon":254},[258],{"name":259,"role":52,"phone":260,"phoneExt":31,"email":261},"Mikhail Kostik","+7 911 120-11-40","kost-mikhail@yandex.ru",{"facility":263,"status":31,"city":250,"state":31,"zip":264,"country":60,"countryCode":61,"cosmosGeoPoint":265,"geoPoint":267,"contacts":268},"Interleukin LLC","194214",{"type":63,"coordinates":266},[254,255],{"lat":255,"lon":254},[269],{"name":270,"role":52,"phone":271,"phoneExt":31,"email":272},"Alexey Maslyansky","+78126022501","esc_4@mail.ru",{"facility":274,"status":31,"city":250,"state":31,"zip":275,"country":60,"countryCode":61,"cosmosGeoPoint":276,"geoPoint":278,"contacts":279},"State Budgetary Healthcare Institution \"Leningrad Regional Clinical Hospital\"","194291",{"type":63,"coordinates":277},[254,255],{"lat":255,"lon":254},[280],{"name":281,"role":52,"phone":282,"phoneExt":31,"email":283},"Elena Ilivanova","8 800 301-47-47","rheum_lokb@mail.ru",{"facility":285,"status":31,"city":250,"state":31,"zip":286,"country":60,"countryCode":61,"cosmosGeoPoint":287,"geoPoint":289,"contacts":290},"Limited Liability Company \"Medical-Sanitary Unit No. 157\" (MSU No. 157)","196066",{"type":63,"coordinates":288},[254,255],{"lat":255,"lon":254},[291],{"name":292,"role":52,"phone":293,"phoneExt":31,"email":294},"Vadim Mazurov","+7 (812) 415-37-00","maz.nwgmu@yandex.ru",{"facility":296,"status":31,"city":297,"state":31,"zip":298,"country":60,"countryCode":61,"cosmosGeoPoint":299,"geoPoint":303,"contacts":304},"State Healthcare Institution \"Regional Clinical Hospital\" of Saratov","Saratov","410053",{"type":63,"coordinates":300},[301,302],45.9901,51.54048,{"lat":302,"lon":301},[305],{"name":306,"role":52,"phone":307,"phoneExt":31,"email":308},"Natalya Nikitina","+7 (8452) 491640","nikina02@yandex.ru",{"facility":310,"status":31,"city":311,"state":31,"zip":312,"country":60,"countryCode":61,"cosmosGeoPoint":313,"geoPoint":317,"contacts":318},"Smolensk Regional Rheumatology Center at the \"RZD-Medicine\" Clinical Hospital (Private Healthcare Institution)","Smolensk","214025",{"type":63,"coordinates":314},[315,316],32.05088,54.77826,{"lat":316,"lon":315},[319],{"name":320,"role":52,"phone":321,"phoneExt":31,"email":322},"Diana Krechikova","8 (4812) 24-50-60","d.krechikova@gmail.com",{"facility":324,"status":31,"city":325,"state":31,"zip":326,"country":60,"countryCode":61,"cosmosGeoPoint":327,"geoPoint":331,"contacts":332},"Siberian State Medical University (Federal State Budgetary Educational Institution of Higher Education of the Ministry of Health of the Russian Federation)","Tomsk","634050",{"type":63,"coordinates":328},[329,330],84.98216,56.50049,{"lat":330,"lon":329},[333],{"name":334,"role":52,"phone":335,"phoneExt":31,"email":336},"Larisa Eliseeva","+7 (3822) 53-05-81","eliseevav@mail.ru",{"facility":338,"status":31,"city":339,"state":31,"zip":340,"country":60,"countryCode":61,"cosmosGeoPoint":341,"geoPoint":345,"contacts":346},"State Budgetary Healthcare Institution \"G.G. Kuvatov Republican Clinical Hospital\"","Ufa","450005",{"type":63,"coordinates":342},[343,344],55.96779,54.74306,{"lat":344,"lon":343},[347],{"name":348,"role":52,"phone":349,"phoneExt":31,"email":350},"Gulshat Fatkhullina","+7 (347) 246-33-30","fgulshatf76@mail.ru",{"facility":352,"status":31,"city":353,"state":31,"zip":354,"country":60,"countryCode":61,"cosmosGeoPoint":355,"geoPoint":359,"contacts":360},"State Healthcare Institution \"City Clinical Emergency Hospital No. 25\"","Volgograd","400117",{"type":63,"coordinates":356},[357,358],44.4976,48.71378,{"lat":358,"lon":357},[361],{"name":362,"role":52,"phone":363,"phoneExt":31,"email":364},"Lyudmila Shilova","+7 (8442) 58-16-61","ludshilova@mail.ru",{"facility":366,"status":31,"city":367,"state":31,"zip":368,"country":60,"countryCode":61,"cosmosGeoPoint":369,"geoPoint":373,"contacts":374},"Yaroslavl State Medical University (Federal State Budgetary Educational Institution of Higher Education of the Ministry of Health of the Russian Federation)","Yaroslavl","150047",{"type":63,"coordinates":370},[371,372],39.87368,57.62987,{"lat":372,"lon":371},[375],{"name":376,"role":52,"phone":377,"phoneExt":31,"email":378},"Natalia Lapkina","+7 (4852) 20-87-08","lanaal@rambler.ru",{"type":380,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR","100640322","phase-3-study-of-the-efficacy-and-safety-of-goflikicept-and-olokizumab-as-the-second-line-therapy-in-patients-with-stills-disease-100640322",false,"NCT07625384","Study of the Efficacy and Safety of Goflikicept and Olokizumab as the Second-line Therapy in Patients With Still's Disease","International Multicenter, Double-blind, Randomized, Placebo-controlled Clinical Study of the Efficacy and Safety of Goflikicept and Olokizumab as the Second-line Therapy in Patients With Still's Disease","Inclusion Criteria:\n\n1. Voluntarily signed and dated Informed Consent Form (ICF) of the patient agreed to take part in this Study\n2. Confirmed diagnosis of Adult-Onset Still's Disease (AOSD) based on the Yamaguchi M. diagnostic criteria\n3. Patient with active disease or low disease activity per DAVID criteria\n4. In case of current corticosteroid (CS) use, doses must be stable for at least 2 weeks prior to Day 0. The maximum allowed dose of CS is 1 mg\u002Fkg\u002Fday, up to 60 mg\u002Fday (prednisolone equivalent)\n5. In case of current nonsteroidal anti-inflammatory drugs (NSAID) use, dose of NSAIDs must be stable for at least 2 weeks prior to Day 0\n6. In case of current methotrexate (MTX) use, the dose of MTX must be stable for at least 4 weeks prior to Day 0. The maximum allowed dose is 30 mg\u002Fweek. In case of prior MTX discontinuation, it must be performed at least 4 weeks before Day 0\n7. Patient's ability and willingness, in the reasonable opinion of the investigator, to attend the clinical center for all scheduled visits, perform study procedures, and comply with protocol requirements, including consent to receive subcutaneous injections by qualified personnel\n8. Women of childbearing potential, defined as all women physiologically capable of becoming pregnant (excluding women who are post-menopausal, defined retrospectively as 12 months of natural amenorrhea with appropriate clinical status, e.g., age-appropriate), must agree to use highly effective methods of contraception throughout the study, starting from the signing of the ICF until at least 8 weeks after the last dose of study treatment; and must have a negative pregnancy test (serum human chorionic gonadotropin, hCG)\n9. Sexually active male participants must agree to use highly effective methods of contraception throughout the study, starting from the signing of the ICF until at least 8 weeks after the last dose of study treatment\n\nExclusion Criteria:\n\n1. Hypersensitivity to the active and\u002For inactive ingredients of the investigational product\n2. Prior use of the following medications:\n\n   * Rilonacept - less than 6 weeks prior to Day 0\n   * Canakinumab - less than 20 weeks prior to Day 0\n   * Anakinra - less than 1 week prior to Day 0\n   * TNF-alpha inhibitors: etanercept less than 2 weeks, adalimumab, certolizumab, or golimumab less than 10 weeks prior to Day 0\n   * IL-6 inhibitors: olokizumab - less than 20 weeks, tocilizumab - less than 16 weeks, or sarilumab less than 8 weeks prior to Day 0\n   * Janus kinase (JAK) inhibitors - less than 1 week prior to Day 0\n   * Immunosuppressants (azathioprine less than 3 days, cyclosporine less than 1 week, mycophenolate mofetil less than 1 week, tacrolimus less than 10 days, mercaptopurine less than 2 days, etc., except for methotrexate) - less than 5 half-lives prior to Day 0\n   * Leflunomide - less than 10 weeks prior to Day 0\n   * Corticosteroid pulse therapy (e.g., intravenous methylprednisolone 250-1000 mg\u002Fday or equivalent dose of dexamethasone for 3 days) - less than 4 weeks (from the completion of pulse therapy) prior to Day 0\n   * Intravenous immunoglobulin (IVIG) - less than 4 weeks prior to Day 0\n   * Other biologic drug with immunosuppressive effects - less than 5 half-lives prior to Day 0\n3. Use of live-attenuated vaccines within less than 3 months prior to Day 0 (start of the treatment period in the study) and\u002For anticipated need for such vaccination within 3 months after completion of the investigational therapy. Live-attenuated vaccines include vaccines against measles, rubella, mumps, varicella, rotavirus, influenza (intranasal), yellow fever, poliomyelitis (oral polio vaccine), as well as vaccines against tuberculosis (BCG), typhoid (oral typhoid vaccine), and epidemic typhus. Immunocompetent household members of the patient must refrain from receiving oral polio vaccine during the patient's participation in the study\n4. Presence of conditions or signs that, in the investigator's opinion, indicate impaired immune response and\u002For significantly increase the risk associated with immunomodulatory therapy, including but not limited to:\n\n   * Active bacterial, fungal, viral, or protozoal infection at the start of the screening period\n   * Opportunistic infections and\u002For Kaposi's sarcoma at the start of screening\n   * Chronic bacterial, fungal, or viral infection requiring systemic parenteral therapy at the start of screening\n   * HIV infection, viral hepatitis B or C, or syphilis (patients with hepatitis B and\u002For C who have received antiviral therapy and have had undetectable viral load for at least 6 months may be eligible, subject to confirmation by an appropriate specialist)\n5. History of active tuberculosis (TB); suspected or confirmed active tuberculosis at present; or signs of active tuberculosis, including chest computed tomography (CT) or chest X-ray findings consistent with pulmonary tuberculosis during screening; or presence of risk factors for tuberculosis, including but not limited to:\n\n   * Living conditions associated with increased risk of exposure (e.g., correctional facilities, homeless shelters) within 1 year prior to randomization\n   * Healthcare workers with unprotected exposure to patients at high risk of TB or with TB within 1 year prior to randomization\n   * Close contact (i.e., prolonged cohabitation for days or weeks, not minutes or hours) with a person with active tuberculosis within 1 year prior to randomization\n6. History of latent TB without adequate treatment, regardless of screening QuantiFERON-TB\u002FT-SPOT.TB results, or a positive QuantiFERON-TB\u002FT-SPOT.TB result at screening. Such patients may be re-screened and enrolled if all of the following are met:\n\n   * Active TB is ruled out by a certified TB specialist\n   * The patient has completed at least 30 days of prophylactic anti-TB therapy for LTBI prior to screening, using country-recommended regimens\n   * The patient agrees to complete the full course of LTBI treatment\n7. Any other significant comorbidities (cardiovascular, neurological, endocrine, renal, gastrointestinal, hepatic, coagulation disorders, other systemic rheumatic diseases, psychiatric disorders, etc.) that, in the investigator's judgment, may adversely affect participation, patient safety, or study results\n8. History of organ transplantation or need for transplantation at screening\n9. Malignancy during screening or within 5 years prior, except adequately treated non-metastatic basal cell or squamous cell carcinoma of the skin, or carcinoma in situ of any type after complete resection\n10. Pregnancy or breastfeeding\n11. Alcohol or substance abuse, in the investigator's opinion\n12. Severe renal impairment: creatinine clearance (Cockcroft-Gault) \\\u003C 30 mL\u002Fmin\n13. Laboratory abnormalities:\n\n    * Absolute neutrophil count \\\u003C 1.5 × 10\\^9\u002FL\n    * Leukocytes \\\u003C 3.5 × 10\\^9\u002FL\n    * Platelets \\\u003C 100 × 10\\^9\u002FL\n    * Hemoglobin ≤ 80 g\u002FL\n    * HbA1c ≥ 8%\n    * ALT and\u002For AST \\> 8 × ULN\n    * AST and\u002For ALT \\> 3 × ULN with bilirubin \\> 1.5 × ULN\n    * Total bilirubin \\> 2 × ULN (except confirmed Gilbert's syndrome)\n14. Participation in another clinical trial at screening or use of any investigational drug within 4 weeks or 5 half-lives (whichever is longer) prior to Visit 1 (start of treatment period)\n15. Presence or suspicion of macrophage activation syndrome (MAS) at screening. MAS criteria includes persistent fever, splenomegaly, elevated or rising serum ferritin levels, cytopenia, abnormal liver function tests, intravascular activation of coagulation, and elevated or rising serum triglyceride levels\n16. Diagnosis of MAS within 2 months prior to Day 0\n17. Prior participation in this clinical study, provided the patient received at least one dose of the investigational product","ALL","18 Years",{"count":391,"type":392},52,"ESTIMATED","INTERVENTIONAL",[395],"PHASE3","The primary objective of the study is to evaluate the efficacy and safety of goflikicept (GFC) and olokizumab (OKZ) in patients with Still's disease",[398],"Still Disease",[400,9,37,21],"Still's Disease","NOT_YET_RECRUITING","2026-05-28",{"date":404,"type":405},"2026-06-04","ACTUAL",{"date":407,"type":392},"2026-05-18",{"date":409,"type":392},"2028-07-01",{"name":47,"class":6},25]