[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100524968":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":34,"responsibleParty":199,"collaborators":202,"id":208,"slug":209,"hasResults":210,"nctId":211,"briefTitle":212,"officialTitle":213,"acronym":214,"eligibilityCriteria":215,"healthyVolunteers":210,"sex":216,"minAge":217,"maxAge":18,"enrollmentInfo":218,"targetDuration":18,"studyType":221,"phases":222,"briefSummary":224,"conditions":225,"keywords":228,"overallStatus":232,"whyStopped":18,"lastUpdateSubmitDate":233,"lastUpdatePostDateStruct":234,"startDateStruct":237,"completionDateStruct":239,"leadSponsor":241,"locationsCount":242},{"fullName":5,"class":6},"University of Dublin, Trinity College","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Imaging surveillance","EXPERIMENTAL","Computed tomography scan every 6 months for 3 years postoperatively. Upper gastrointestinal endoscopy at 12 months postoperatively.",[13],"Other: Surveillance protocol",{"label":15,"type":16,"description":17,"interventionNames":18},"Clinical surveillance","NO_INTERVENTION","Clinical review every 6 months for 3 years postoperatively with further investigation according to symptoms.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Surveillance protocol","Imaging surveillance will entail a computed tomography scan of the chest, abdomen and pelvis, as well as clinical review, every 6 months for 36 months post surgery along with an endoscopy at 12 months post surgery.",[9],[25],{"name":26,"affiliation":27,"role":28},"Jessie A Elliott, PhD FRCS","Trinity St. James's Cancer Institute","PRINCIPAL_INVESTIGATOR",[30],{"name":26,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","+353 1 410 3900","SARONG@tcd.ie",[35,52,67,79,90,105,118,129,140,153,164,175,188],{"facility":36,"status":18,"city":37,"state":18,"zip":18,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"University Hospital Cologne","Cologne","Germany","DE",{"type":41,"coordinates":42},"Point",[43,44],6.95,50.93333,{"lat":44,"lon":43},[47,49],{"name":48,"role":31,"phone":18,"phoneExt":18,"email":18},"Wolfgang Schröder",{"name":50,"role":51,"phone":18,"phoneExt":18,"email":18},"Thomas Zander","SUB_INVESTIGATOR",{"facility":53,"status":18,"city":54,"state":18,"zip":18,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Mercy University Hospital","Cork","Ireland","IE",{"type":41,"coordinates":58},[59,60],-8.47061,51.89797,{"lat":60,"lon":59},[63,65],{"name":64,"role":31,"phone":18,"phoneExt":18,"email":18},"Evelyn Flanagan, BSc MSc PhD MBA",{"name":66,"role":28,"phone":18,"phoneExt":18,"email":18},"Thomas Murphy",{"facility":27,"status":18,"city":68,"state":18,"zip":18,"country":55,"countryCode":56,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Dublin",{"type":41,"coordinates":70},[71,72],-6.24889,53.33306,{"lat":72,"lon":71},[75,77],{"name":76,"role":31,"phone":18,"phoneExt":18,"email":18},"Claire L Donohoe, PhD FRCS MEd",{"name":78,"role":51,"phone":18,"phoneExt":18,"email":18},"John V Reynolds, MD FRCS",{"facility":80,"status":18,"city":81,"state":18,"zip":18,"country":55,"countryCode":56,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"Galway University Hospital","Galway",{"type":41,"coordinates":83},[84,85],-9.05095,53.27245,{"lat":85,"lon":84},[88],{"name":89,"role":31,"phone":18,"phoneExt":18,"email":18},"Paul Carroll",{"facility":91,"status":18,"city":92,"state":18,"zip":18,"country":93,"countryCode":94,"cosmosGeoPoint":95,"geoPoint":99,"contacts":100},"Fondazione Policlinico Universitario Agostino 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Aahlin",{"facility":130,"status":18,"city":131,"state":18,"zip":18,"country":108,"countryCode":109,"cosmosGeoPoint":132,"geoPoint":136,"contacts":137},"St. Olav University Hospital","Trondheim",{"type":41,"coordinates":133},[134,135],10.39506,63.43049,{"lat":135,"lon":134},[138],{"name":139,"role":31,"phone":18,"phoneExt":18,"email":18},"Lars Cato Rekstad",{"facility":141,"status":18,"city":142,"state":18,"zip":18,"country":143,"countryCode":144,"cosmosGeoPoint":145,"geoPoint":149,"contacts":150},"Linköping University Hospital","Linköping","Sweden","SE",{"type":41,"coordinates":146},[147,148],15.62157,58.41086,{"lat":148,"lon":147},[151],{"name":152,"role":31,"phone":18,"phoneExt":18,"email":18},"David Edholm",{"facility":154,"status":18,"city":155,"state":18,"zip":18,"country":143,"countryCode":144,"cosmosGeoPoint":156,"geoPoint":160,"contacts":161},"Skåne University Hospital","Lund",{"type":41,"coordinates":157},[158,159],13.19321,55.70584,{"lat":159,"lon":158},[162],{"name":163,"role":31,"phone":18,"phoneExt":18,"email":18},"Jan Johansson",{"facility":165,"status":18,"city":166,"state":18,"zip":18,"country":143,"countryCode":144,"cosmosGeoPoint":167,"geoPoint":171,"contacts":172},"Örebro University Hospital","Örebro",{"type":41,"coordinates":168},[169,170],15.2066,59.27412,{"lat":170,"lon":169},[173],{"name":174,"role":31,"phone":18,"phoneExt":18,"email":18},"Eva Szabo",{"facility":176,"status":18,"city":177,"state":18,"zip":18,"country":143,"countryCode":144,"cosmosGeoPoint":178,"geoPoint":182,"contacts":183},"Karolinska Institutet","Stockholm",{"type":41,"coordinates":179},[180,181],18.06871,59.32938,{"lat":181,"lon":180},[184,186],{"name":185,"role":31,"phone":18,"phoneExt":18,"email":18},"Maria Lampi",{"name":187,"role":51,"phone":18,"phoneExt":18,"email":18},"Magnus Nilsson",{"facility":189,"status":18,"city":190,"state":18,"zip":18,"country":143,"countryCode":144,"cosmosGeoPoint":191,"geoPoint":195,"contacts":196},"Uppsala University Hospital","Uppsala",{"type":41,"coordinates":192},[193,194],17.63889,59.85882,{"lat":194,"lon":193},[197],{"name":198,"role":31,"phone":18,"phoneExt":18,"email":18},"Jakob Hedberg",{"type":28,"investigatorFullName":200,"investigatorTitle":201,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Dr Jessie A Elliott","Clinical Lecturer",[203,205,207],{"name":27,"class":204},"UNKNOWN",{"name":206,"class":6},"University of Oxford",{"name":176,"class":6},"100524968","phase-3-surveillance-after-resection-of-oesophageal-and-gastric-cancer-sarong-ii-trial-100524968",false,"NCT06115629","Surveillance After Resection of Oesophageal aNd Gastric Cancer (SARONG-II) Trial","Open Label International Multicentre Randomised Controlled Trial of Intensive Surveillance vs. Standard Postoperative Follow-up in Patients Undergoing Surgical Resection for Oesophageal and Gastric Cancer","SARONG-II","A patient will be eligible for inclusion in this study if all of the following criteria apply:\n\n1. Has undergone surgical resection for curatively intended treatment of oesophageal or gastric cancer (adenocarcinoma and squamous cell carcinoma) with or without neoadjuvant\u002Fadjuvant chemotherapy or radiotherapy or immunotherapy (or in combination).\n2. Aged 18 years or over\n3. Willing and able to give informed consent\n\nA patient with not be eligible for the trial if any of the following apply:\n\n1\\. Other cancer(s) undergoing treatment or surveillance","ALL","18 Years",{"count":219,"type":220},952,"ESTIMATED","INTERVENTIONAL",[223],"PHASE3","Cancer of the food pipe (oesophagus) and stomach are increasingly common. Currently, most patients with cancer of the oesophagus and stomach are treated with surgery with or without additional chemotherapy or radiotherapy. In recent years there have been improvements in survival from these two cancers, due to better therapies, less invasive surgery and earlier detection. Despite these improvements, in around half of patients treated with surgery, the cancer will return, usually within the first three years.\n\nAt present there is very little evidence as to how patients who have been treated for cancer of the oesophagus or stomach should be followed up after surgery and whether different methods of follow-up could improve survival. Currently, national and international guidelines do not provide consistency in their recommendations for follow-up after surgery.\n\nThe SARONG-II study will investigate if regular radiological scans can lead to earlier detection of a cancer returning, at a stage when it may be more readily treatable. This means that participants who agree to take part will be allocated by chance to either more intensive imaging surveillance (including regular radiological scans and a camera test (endoscopy)) or clinical follow-up.\n\nThe study aims to recruit at least 952 participants in Europe over a 32-month period. Patients undergoing surgery for oesophageal or stomach cancer will be invited to participate in the study at around 4 to 8 weeks after their surgery.\n\n(i) The imaging surveillance group will receive a review in clinic or by telephone with a member of the surgical team, and a radiological scan at 6, 12, 18, 24, 30 and 36 months after randomisation. They will also receive endoscopy at 12 months after randomisation (ii) The clinical surveillance group will receive a review in clinic or by telephone at 6, 12, 18, 24, 30 and 36 months. After this they will be either discharged to their local doctor or receive a review in clinic with a member of the surgical team every year according to local practice\n\nThe main aim of this study will be to determine whether earlier detection of cancer through more intensive follow-up results in improved survival and better quality of life for patients with oesophagus or stomach cancer. The investigators anticipate the results of the study may have significant practice-changing impact for patients undergoing follow-up after surgery for oesophagus and stomach cancer.",[226,227],"Esophageal Cancer","Gastric Cancer",[229,230,231],"Surveillance","Cancer recurrence","Quality of life","NOT_YET_RECRUITING","2023-10-29",{"date":235,"type":236},"2023-11-03","ACTUAL",{"date":238,"type":220},"2023-11",{"date":240,"type":220},"2029-11",{"name":5,"class":6},13]