[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551977":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":31,"responsibleParty":45,"collaborators":12,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":50,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":12,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":12,"overallStatus":33,"whyStopped":12,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Samsung Medical Center","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"A group","NO_INTERVENTION","Only standard treatment is administered. The standard treatment includes targeted cancer therapy, immunotherapy, or monotherapy with each therapeutic agent.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"B group","EXPERIMENTAL","This group receives concurrent partial nephrectomy radiotherapy for all metastatic lesions in addition to standard treatment.",[18],"Radiation: SBRT(Stereotatic Body Radiation Therapy)",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"RADIATION","SBRT(Stereotatic Body Radiation Therapy)","Patients will receive treatment for one to two weeks, one to five times per region.",[14],[26],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Won Park, M.D., Ph.D.","CONTACT","+82-2-3410-2616","wonro.park@samsung.com",[32],{"facility":5,"status":33,"city":34,"state":12,"zip":35,"country":36,"countryCode":12,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Seoul","06351","South Korea",{"type":38,"coordinates":39},"Point",[40,41],126.9784,37.566,{"lat":41,"lon":40},[44],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},{"type":46,"investigatorFullName":47,"investigatorTitle":27,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Won Park","100551977","phase-3-systemic-treatment-alone-versus-systemic-treatment-plus-radiotherapy-in-oligometastatic-renal-cell-carcinoma-100551977",false,"NCT06467097","Systemic Treatment Alone Versus Systemic Treatment Plus Radiotherapy in Oligometastatic Renal Cell Carcinoma","A Phase Ⅲ Randomized Study Systemic Treatment Alone Versus Systemic Treatment Plus Stereotactic Abative Body Radiotherapy for Patients With Oligometastatic Renal Cell Carcinoma: SABLOR Study","SABLOR","Inclusion Criteria:\n\n1. Patients with metastatic renal cell carcinoma classified within the ESTRO\u002FEORTC classification system as having ≤ 5 metastases, ≤ 3 metastatic organs, and meeting criteria for new, recurrent, or induced metastases.\n2. Patients aged 20 to 80 years.\n3. Patients with individual metastases ≤ 5 cm in longest diameter.\n4. Patients with primary tumors surgically removed or scheduled for surgery.\n5. Patients histologically diagnosed with clear cell carcinoma.\n6. Patients with ECOG performance status 0-1.\n7. Patients with normal major organ function and bone marrow function meeting specific criteria: WBC ≥ 2,000\u002FμL, neutrophils ≥ 1,000\u002FμL, platelets ≥ 50,000\u002FμL.\n8. Patients who understand the contents of the informed consent form, voluntarily consent to participate in the study, and sign the informed consent form.\n9. Patients who agree to use contraception from the time of signing the consent form until 1 year after the last standard systemic therapy.\n10. Breastfeeding women who agree to stop breastfeeding for at least 5 months after the last standard systemic therapy.\n11. Patients with visible tumors outside the scope of tumor removal surgery (surgical therapy) for metastatic lesions.\n\nExclusion Criteria:\n\n1. Patients with total bilirubin \\> 3.6 mg\u002FdL.\n2. Patients with AST \\>160 U\u002FL, ALT \\> 165 U\u002FL.\n3. Patients unable to maintain position for partial nephrectomy radiotherapy.\n4. Patients with a history of radiotherapy to metastatic renal cell carcinoma or surrounding areas.\n5. Patients with confirmed brain, peritoneal, or pleural metastases.\n6. Patients diagnosed with another solid tumor and treated within 2 years or with residual lesions.\n7. Patients who do not consent to participate in the study.\n8. Pregnant patients.","ALL","20 Years","80 Years",{"count":60,"type":61},88,"ESTIMATED","INTERVENTIONAL",[64],"PHASE3","To evaluate whether incorporating locoregional radiotherapy in the treatment of oligometastatic renal cell carcinoma, including inductive oligometastases, along with standard systemic therapy, contributes to improved progression-free survival rates for patients.",[67],"Kidney Neoplasm","2024-06-18",{"date":70,"type":71},"2024-06-20","ACTUAL",{"date":73,"type":71},"2024-04-16",{"date":75,"type":61},"2031-02-13",{"name":5,"class":6},1]