[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601757":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":35,"centralContacts":35,"locations":48,"responsibleParty":69,"collaborators":35,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":5,"acronym":35,"eligibilityCriteria":78,"healthyVolunteers":75,"sex":79,"minAge":80,"maxAge":35,"enrollmentInfo":81,"targetDuration":35,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":92,"whyStopped":35,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Far Eastern Memorial Hospital","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"mirabegron","ACTIVE_COMPARATOR","mirabegron 25 mg",[13],"Drug: Mirabegron 25mg",{"label":15,"type":10,"description":16,"interventionNames":17},"Solifenacin","Solifenacin 5mg",[18],"Drug: Solifenacin 5 mg",{"label":20,"type":10,"description":21,"interventionNames":22},"Tolterodine","Tolterodine 4mg",[23],"Drug: Tolterodine 4 mg",{"label":25,"type":10,"description":26,"interventionNames":27},"Oxybutynin ER","Oxybutynin ER 5mg",[28],"Drug: Oxybutynin ER 5 mg",[30,36,40,44],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"DRUG","Mirabegron 25mg","Taking 25 mg mirabegron in the nighttime",[9],null,{"type":31,"name":37,"description":38,"armGroupLabels":39,"otherNames":35},"Solifenacin 5 mg","Taking 5 mg solifenacin in the nighttime",[15],{"type":31,"name":41,"description":42,"armGroupLabels":43,"otherNames":35},"Tolterodine 4 mg","Taking 5 mg tolterodine in the nighttime",[20],{"type":31,"name":45,"description":46,"armGroupLabels":47,"otherNames":35},"Oxybutynin ER 5 mg","Taking 5 mg oxybutynin ER in the nighttime",[25],[49],{"facility":50,"status":35,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital,","Banqiao District","New Taipei","22050","Taiwan","TW",{"type":57,"coordinates":58},"Point",[59,60],121.46719,25.01427,{"lat":60,"lon":59},[63],{"name":64,"role":65,"phone":66,"phoneExt":67,"email":68},"Sheng-Mou Hsiao, M.D.","CONTACT","+886-2-89667000","1818","smhsiao2@gmail.com",{"type":70,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"PRINCIPAL_INVESTIGATOR","Sheng-Mou Hsiao","Chief and Professor, Department of Obstetrics and Gynecology","100601757","phase-3-the-effect-of-nighttime-mirabegron-solifenacin-tolterodine-or-oxybutynin-on-nocturia-sexual-function-autonomic-function-and-lower-urinary-tract-blood-flow-perfusion-in-women-with-overactive-bladder-syndrome-randomized-controlled-trial-100601757",false,"NCT07114640","The Effect of Nighttime Mirabegron, Solifenacin, Tolterodine, or Oxybutynin on Nocturia, Sexual Function, Autonomic Function, and Lower Urinary Tract Blood Flow Perfusion in Women With Overactive Bladder Syndrome: Randomized Controlled Trial","Inclusion Criteria:\n\n* \\>18 years old.\n* female patients with overactive bladder syndrome\n\nExclusion Criteria:\n\n* Clinically significant dysuria (inability to urinate, difficulty urinating).\n* Severe stress urinary incontinence (urinary incontinence caused by coughing).\n* Mixed urinary incontinence mainly caused by stress urinary incontinence (urinary incontinence caused by coughing as the main symptom).\n* Contraindications to antimuscarinic drugs or adrenergic receptor agonists.","FEMALE","18 Years",{"count":82,"type":83},220,"ESTIMATED","INTERVENTIONAL",[86],"PHASE3","The optimal medication for women with nocturia remains uncertain. This clinical trial aimed to determine the most effective medication for women with overactive bladder and nocturia. Its primary objectives were to answer the following questions:\n\nWhich medication is most effective for women with nocturia? Which medication has the least effect on heart rate variability in women with nocturia?",[89],"Urinary Bladder, Overactive",[91],"autonomic nerve system, nocturia, psychologic distress, sexual function, bladder blood perfusion, heart rate variability, overactive bladder syndrome","NOT_YET_RECRUITING","2025-08-04",{"date":95,"type":96},"2025-08-11","ACTUAL",{"date":98,"type":83},"2025-08-07",{"date":100,"type":83},"2028-12-31",{"name":5,"class":6},1]