[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575671":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":56,"locations":66,"responsibleParty":84,"collaborators":87,"id":95,"slug":96,"hasResults":97,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":31,"eligibilityCriteria":101,"healthyVolunteers":97,"sex":102,"minAge":103,"maxAge":104,"enrollmentInfo":105,"targetDuration":31,"studyType":108,"phases":109,"briefSummary":111,"conditions":112,"keywords":114,"overallStatus":124,"whyStopped":31,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":134},{"fullName":5,"class":6},"Indonesia University","OTHER",[8,17],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo","PLACEBO_COMPARATOR","this arm will receive placebo cleanser, placebo combination cream, and placebo spot cream every morning and evening, and then placebo cleanser, placebo combination cream and adapalene 0,1% every night",[13,14,15,16],"Drug: Adapalene 0,1% cream","Drug: placebo cleanser","Drug: placebo cream combination","Drug: placebo spot cream",{"label":18,"type":19,"description":20,"interventionNames":21},"Treatment","ACTIVE_COMPARATOR","this arm will receive cleanser, containing Triethyl citrate, Pyruvic acid, combination cream, containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic acid, and spot cream, containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Honokiol, every morning and evening, and then cleanser, containing Triethyl citrate, Pyruvic acid, combination cream, containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic acid, and adapalene 0,1% cream every night",[22,23,24,13],"Drug: Cleanser","Drug: Combination cream","Drug: spot cream",[26,32,36,40,44,48,52],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","Cleanser","Cleanser consist of Triethyl citrate and Pyruvic acid, will be given to subjects to be applied every morning, evening and night in group 2",[18],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Combination cream","combination cream consist of Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic acid will be given to subjects to be applied every morning, evening and night in group 2",[18],{"type":27,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"spot cream","spot cream consist of Triethyl citrate, Ethyl linoleate, GT peptide-10, Honokiol, will be given to subjects to be applied every morning and evening in group 2",[18],{"type":27,"name":41,"description":42,"armGroupLabels":43,"otherNames":31},"Adapalene 0,1% cream","adapalene 0.1% cream will be given to subjects to be applied every night in group 1 and 2",[9,18],{"type":27,"name":45,"description":46,"armGroupLabels":47,"otherNames":31},"placebo cleanser","placebo cleanser will be given to subjects to be applied every morning, evening and night in group 1",[9],{"type":27,"name":49,"description":50,"armGroupLabels":51,"otherNames":31},"placebo cream combination","placebo cream combination will be given to subjects to be applied every morning, evening and night in group 1",[9],{"type":27,"name":53,"description":54,"armGroupLabels":55,"otherNames":31},"placebo spot cream","placebo spot cream will be given to subjects to be applied every morning and evening in group 1",[9],[57,62],{"name":58,"role":59,"phone":60,"phoneExt":31,"email":61},"Prof. Dr. dr. Irma Bernadette, Sp.DVE, Subsp. D.K.E Sitohang","CONTACT","+62818130761","irma_bernadette@yahoo.com",{"name":63,"role":59,"phone":64,"phoneExt":31,"email":65},"dr. Lilik Norawati, Sp.DVE","+628121107149","liliknora21@gmail.com",[67],{"facility":68,"status":31,"city":69,"state":70,"zip":71,"country":72,"countryCode":73,"cosmosGeoPoint":74,"geoPoint":79,"contacts":80},"Rumah Sakit Pusat Angkatan Darat Gatot Soebroto","Jakarta","Jakarta Pusat","10410","Indonesia","ID",{"type":75,"coordinates":76},"Point",[77,78],106.84513,-6.21462,{"lat":78,"lon":77},[81,83],{"name":82,"role":59,"phone":60,"phoneExt":31,"email":61},"Prof. Dr. dr. Irma Bernadette, Sp.DVE, Subsp. D.K.E",{"name":63,"role":59,"phone":64,"phoneExt":31,"email":65},{"type":85,"investigatorFullName":86,"investigatorTitle":82,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"SPONSOR_INVESTIGATOR","Dr.dr.Irma Bernadette, SpKK (K)",[88,91,93],{"name":89,"class":90},"Indonesian Society of Dermatology and Venereology","UNKNOWN",{"name":92,"class":90},"College of Dermatologist and Venereologist",{"name":94,"class":6},"Indonesia Medical Education and Research Institute","100575671","phase-3-the-effectiveness-and-safety-of-cleanser-containing-triethyl-citrate-pyruvic-acid-combination-cream-containing-triethyl-citrate-ethyl-linoleate-gt-peptide-10-salicylic-acid-05-zinc-lactate-hyaluronic-acid-and-spot-cream-containing-triethyl-citrate-ethyl-linoleate-gt-peptide-10-honokiol-100575671",false,"NCT06775314","The Effectiveness and Safety of Cleanser Containing Triethyl Citrate, Pyruvic Acid, Combination Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic Acid and Spot Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Honokiol","The Effectiveness and Safety of Cleanser Containing Triethyl Citrate, Pyruvic Acid, Combination Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic Acid and Spot Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Honokiol As Adjuvant Therapy for Mild to Moderate Acne Vulgaris","Inclusion Criteria:\n\n* Female and male aged 15-50 years\n* mild to moderate acne vulgaris according to IAEM (Indonesian Acne Expert Meeting) scale and GEA ( Global Acne Severity) scale\n* The subject is willing to participate in the study until it is finished\n\nExclusion Criteria:\n\n* History of allergy to dermocosmetic products\n* Undergoing other acne therapy, medication, or invasive action in the last month\n* Pregnant or breastfeeding subjects","ALL","15 Years","50 Years",{"count":106,"type":107},102,"ESTIMATED","INTERVENTIONAL",[110],"PHASE3","The goal of this clinical study is to learn the effectiveness and safety of Cleanser containing Triethyl citrate, Pyruvic acid, Combination cream containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic acid 0,5%, Zinc lactate, Hyaluronic acid and Spot cream containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Honokiol as Adjuvant Therapy for Mild to Moderate Acne Vulgaris. This research aims to answer the main questions, those are :\n\n1. How is the effectiveness of Cleanser containing Triethyl citrate, Pyruvic acid, Combination cream containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic acid 0,5%, Zinc lactate, Hyaluronic acid and Spot cream containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Honokiol as Adjuvant Therapy for Mild to Moderate Acne Vulgaris?\n2. How is the safety of Cleanser containing Triethyl citrate, Pyruvic acid, Combination cream containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic acid 0,5%, Zinc lactate, Hyaluronic acid and Spot cream containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Honokiol as Adjuvant Therapy for Mild to Moderate Acne Vulgaris?\n\nParticipants are males and females between 15-50 years old. Participants will be examined by dermatologist, and will be photographed in five different positions, and also evaluated by janus facial analysis system. The participants are asked to use Cleanser containing Triethyl citrate, Pyruvic acid, Combination cream containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic acid 0,5%, Zinc lactate, Hyaluronic acid and Spot cream containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Honokiol as Adjuvant Therapy. The participants will be evaluated in 28, 56 and 84 days after the treatment.",[113],"Acne Vulgaris",[115,116,117,118,119,120,121,122,123],"acne vulgaris","Triethyl citrate","Pyruvic acid","Ethyl linoleate","GT peptide-10","Salicylic acid 0,5%","Zinc lactate","Hyaluronic acid","Honokiol","NOT_YET_RECRUITING","2025-01-14",{"date":127,"type":128},"2025-01-16","ACTUAL",{"date":130,"type":107},"2025-03-01",{"date":132,"type":107},"2025-06-30",{"name":86,"class":6},1]