[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640722":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":34,"locations":39,"responsibleParty":564,"collaborators":11,"id":566,"slug":567,"hasResults":568,"nctId":569,"briefTitle":570,"officialTitle":571,"acronym":11,"eligibilityCriteria":572,"healthyVolunteers":568,"sex":573,"minAge":574,"maxAge":575,"enrollmentInfo":576,"targetDuration":11,"studyType":579,"phases":580,"briefSummary":582,"conditions":583,"keywords":585,"overallStatus":587,"whyStopped":11,"lastUpdateSubmitDate":588,"lastUpdatePostDateStruct":589,"startDateStruct":592,"completionDateStruct":594,"leadSponsor":596,"locationsCount":597},{"fullName":5,"class":6},"Xiamen Amoytop Biotech Co., Ltd.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Inpegsomatropin Injection Group","EXPERIMENTAL",null,[13],"Drug: Inpegsomatropin-Injection",{"label":15,"type":16,"description":11,"interventionNames":17},"Givopegsomatropin Solution Injection Group","ACTIVE_COMPARATOR",[18],"Drug: Givopegsomatropin Solution Injection",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DRUG","Inpegsomatropin-Injection","Inpegsomatropin injection, 280 μg\u002Fkg\u002Fweek, s.c., once weekly, for 52 weeks.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Givopegsomatropin Solution Injection","Givopegsomatropin Solution Injection, 200 μg\u002Fkg\u002Fweek, s.c., once weekly, for 52 weeks.",[15],[30],{"name":31,"affiliation":32,"role":33},"Xiaoping Luo","Tongji Hospital","PRINCIPAL_INVESTIGATOR",[35],{"name":31,"role":36,"phone":37,"phoneExt":11,"email":38},"CONTACT","15671671188","xpluo@tjh.tjmu.edu.cn",[40,54,65,73,81,89,100,111,122,133,144,152,157,165,176,184,195,206,217,228,239,250,261,272,283,294,305,316,327,335,343,351,362,373,384,395,406,417,428,436,447,458,468,476,487,498,509,520,531,542,553],{"facility":41,"status":11,"city":42,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Anyang Maternal and Child Health Hospital","Anyang","China","CN",{"type":46,"coordinates":47},"Point",[48,49],114.38278,36.096,{"lat":49,"lon":48},[52],{"name":53,"role":36,"phone":11,"phoneExt":11,"email":11},"Huiping An",{"facility":55,"status":11,"city":56,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Beijing Children's Hospital, Capital Medical University","Beijing",{"type":46,"coordinates":58},[59,60],116.39723,39.9075,{"lat":60,"lon":59},[63],{"name":64,"role":36,"phone":11,"phoneExt":11,"email":11},"Di Wu",{"facility":66,"status":11,"city":56,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":67,"geoPoint":69,"contacts":70},"Capital Institute of Pediatrics, Capital Medical University",{"type":46,"coordinates":68},[59,60],{"lat":60,"lon":59},[71],{"name":72,"role":36,"phone":11,"phoneExt":11,"email":11},"Bingyan Cao",{"facility":74,"status":11,"city":56,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":75,"geoPoint":77,"contacts":78},"Peking Union Medical College Hospital, Chinese Academy of Medical Sciences",{"type":46,"coordinates":76},[59,60],{"lat":60,"lon":59},[79],{"name":80,"role":36,"phone":11,"phoneExt":11,"email":11},"Hui Pan",{"facility":82,"status":11,"city":56,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":83,"geoPoint":85,"contacts":86},"Peking University First Hospital",{"type":46,"coordinates":84},[59,60],{"lat":60,"lon":59},[87],{"name":88,"role":36,"phone":11,"phoneExt":11,"email":11},"Yanling Yang",{"facility":90,"status":11,"city":91,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":92,"geoPoint":96,"contacts":97},"The Second Xiangya Hospital of Central South University","Changsha",{"type":46,"coordinates":93},[94,95],112.97087,28.19874,{"lat":95,"lon":94},[98],{"name":99,"role":36,"phone":11,"phoneExt":11,"email":11},"Xingxing Zhang",{"facility":101,"status":11,"city":102,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":103,"geoPoint":107,"contacts":108},"Chengdu Women's and Children's Central Hospital","Chengdu",{"type":46,"coordinates":104},[105,106],104.06667,30.66667,{"lat":106,"lon":105},[109],{"name":110,"role":36,"phone":11,"phoneExt":11,"email":11},"Xinran Cheng",{"facility":112,"status":11,"city":113,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":114,"geoPoint":118,"contacts":119},"Children's Hospital of Chongqing Medical University","Chongqing",{"type":46,"coordinates":115},[116,117],106.55771,29.56026,{"lat":117,"lon":116},[120],{"name":121,"role":36,"phone":11,"phoneExt":11,"email":11},"Min Zhu",{"facility":123,"status":11,"city":124,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":125,"geoPoint":129,"contacts":130},"The First Affiliated Hospital of Dalian Medical University","Dalian",{"type":46,"coordinates":126},[127,128],121.60222,38.91222,{"lat":128,"lon":127},[131],{"name":132,"role":36,"phone":11,"phoneExt":11,"email":11},"Luyi Ma",{"facility":134,"status":11,"city":135,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":136,"geoPoint":140,"contacts":141},"Guangdong Provincial Maternal and Child Health Hospital","Guangzhou",{"type":46,"coordinates":137},[138,139],113.25,23.11667,{"lat":139,"lon":138},[142],{"name":143,"role":36,"phone":11,"phoneExt":11,"email":11},"Shu Liu",{"facility":145,"status":11,"city":135,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":146,"geoPoint":148,"contacts":149},"Sun Yat-sen Memorial Hospital, Sun Yat-sen University",{"type":46,"coordinates":147},[138,139],{"lat":139,"lon":138},[150],{"name":151,"role":36,"phone":11,"phoneExt":11,"email":11},"Liyang Liang",{"facility":153,"status":11,"city":135,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":154,"geoPoint":156,"contacts":11},"The First Affiliated Hospital of Sun Yat-sen University",{"type":46,"coordinates":155},[138,139],{"lat":139,"lon":138},{"facility":158,"status":11,"city":135,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":159,"geoPoint":161,"contacts":162},"The Third Affiliated Hospital of Sun Yat-sen University",{"type":46,"coordinates":160},[138,139],{"lat":139,"lon":138},[163],{"name":164,"role":36,"phone":11,"phoneExt":11,"email":11},"Shunye Zhu",{"facility":166,"status":11,"city":167,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":168,"geoPoint":172,"contacts":173},"The First Affiliated Hospital, Zhejiang University School of Medicine","Hangzhou",{"type":46,"coordinates":169},[170,171],120.16142,30.29365,{"lat":171,"lon":170},[174],{"name":175,"role":36,"phone":11,"phoneExt":11,"email":11},"Chunlin Wang",{"facility":177,"status":11,"city":167,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":178,"geoPoint":180,"contacts":181},"Zhejiang Provincial Hospital of Traditional Chinese Medicine",{"type":46,"coordinates":179},[170,171],{"lat":171,"lon":170},[182],{"name":183,"role":36,"phone":11,"phoneExt":11,"email":11},"Lan Li",{"facility":185,"status":11,"city":186,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":187,"geoPoint":191,"contacts":192},"The First Affiliated Hospital of Hebei North University","Hebei",{"type":46,"coordinates":188},[189,190],116.17968,25.93504,{"lat":190,"lon":189},[193],{"name":194,"role":36,"phone":11,"phoneExt":11,"email":11},"Zhengrong Xu",{"facility":196,"status":11,"city":197,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":198,"geoPoint":202,"contacts":203},"The First Affiliated Hospital of Henan University of Science and Technology","Henan",{"type":46,"coordinates":199},[200,201],112.22494,37.92189,{"lat":201,"lon":200},[204],{"name":205,"role":36,"phone":11,"phoneExt":11,"email":11},"Dan Lou",{"facility":207,"status":11,"city":208,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":209,"geoPoint":213,"contacts":214},"Huzhou Central Hospital","Huzhou",{"type":46,"coordinates":210},[211,212],120.0933,30.8703,{"lat":212,"lon":211},[215],{"name":216,"role":36,"phone":11,"phoneExt":11,"email":11},"Wei Qiu",{"facility":218,"status":11,"city":219,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":220,"geoPoint":224,"contacts":225},"Jiangxi Provincial Children's Hospital","Jiangxi",{"type":46,"coordinates":221},[222,223],105.19994,33.99934,{"lat":223,"lon":222},[226],{"name":227,"role":36,"phone":11,"phoneExt":11,"email":11},"Yu Yang",{"facility":229,"status":11,"city":230,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":231,"geoPoint":235,"contacts":236},"The First Hospital of Jilin University","Jilin City",{"type":46,"coordinates":232},[233,234],126.5608,43.84652,{"lat":234,"lon":233},[237],{"name":238,"role":36,"phone":11,"phoneExt":11,"email":11},"Yining Zhang",{"facility":240,"status":11,"city":241,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":242,"geoPoint":246,"contacts":247},"Shandong Provincial Hospital","Jinan",{"type":46,"coordinates":243},[244,245],116.99722,36.66833,{"lat":245,"lon":244},[248],{"name":249,"role":36,"phone":11,"phoneExt":11,"email":11},"Yan Sun",{"facility":251,"status":11,"city":252,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":253,"geoPoint":257,"contacts":258},"Affiliated Hospital of Jining Medical University","Jining",{"type":46,"coordinates":254},[255,256],116.58139,35.405,{"lat":256,"lon":255},[259],{"name":260,"role":36,"phone":11,"phoneExt":11,"email":11},"Mei Zhang",{"facility":262,"status":11,"city":263,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":264,"geoPoint":268,"contacts":269},"Kunming Children's Hospital","Kunming",{"type":46,"coordinates":265},[266,267],102.71833,25.03889,{"lat":267,"lon":266},[270],{"name":271,"role":36,"phone":11,"phoneExt":11,"email":11},"Na Tao",{"facility":273,"status":11,"city":274,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":275,"geoPoint":279,"contacts":280},"Gansu Provincial People's Hospital","Lanzhou",{"type":46,"coordinates":276},[277,278],103.83987,36.05701,{"lat":278,"lon":277},[281],{"name":282,"role":36,"phone":11,"phoneExt":11,"email":11},"Juxiang Liu",{"facility":284,"status":11,"city":285,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":286,"geoPoint":290,"contacts":291},"The Second Affiliated Hospital of Guangxi Medical University","Nanning",{"type":46,"coordinates":287},[288,289],108.31667,22.81667,{"lat":289,"lon":288},[292],{"name":293,"role":36,"phone":11,"phoneExt":11,"email":11},"Xin Fan",{"facility":295,"status":11,"city":296,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":297,"geoPoint":301,"contacts":302},"Pingxiang People's Hospital","Pingxiang",{"type":46,"coordinates":298},[299,300],113.85353,27.61672,{"lat":300,"lon":299},[303],{"name":304,"role":36,"phone":11,"phoneExt":11,"email":11},"Guangping Qin",{"facility":306,"status":11,"city":307,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":308,"geoPoint":312,"contacts":313},"Qilu Hospital of Shandong University","Qilu",{"type":46,"coordinates":309},[310,311],104.34781,34.07249,{"lat":311,"lon":310},[314],{"name":315,"role":36,"phone":11,"phoneExt":11,"email":11},"Aihua Cao",{"facility":317,"status":11,"city":318,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":319,"geoPoint":323,"contacts":324},"Ruijin Hospital, Shanghai Jiao Tong University School of Medicine","Shanghai",{"type":46,"coordinates":320},[321,322],121.45806,31.22222,{"lat":322,"lon":321},[325],{"name":326,"role":36,"phone":11,"phoneExt":11,"email":11},"Wenli Lu",{"facility":328,"status":11,"city":318,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":329,"geoPoint":331,"contacts":332},"Shanghai Children's Hospital",{"type":46,"coordinates":330},[321,322],{"lat":322,"lon":321},[333],{"name":334,"role":36,"phone":11,"phoneExt":11,"email":11},"Fei Wang",{"facility":336,"status":11,"city":318,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":337,"geoPoint":339,"contacts":340},"Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine",{"type":46,"coordinates":338},[321,322],{"lat":322,"lon":321},[341],{"name":342,"role":36,"phone":11,"phoneExt":11,"email":11},"Yu Ding",{"facility":344,"status":11,"city":318,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":345,"geoPoint":347,"contacts":348},"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine",{"type":46,"coordinates":346},[321,322],{"lat":322,"lon":321},[349],{"name":350,"role":36,"phone":11,"phoneExt":11,"email":11},"Wenjuan Qiu",{"facility":352,"status":11,"city":353,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":354,"geoPoint":358,"contacts":359},"The Second Affiliated Hospital of Shaanxi University of Chinese Medicine","Shanxi",{"type":46,"coordinates":355},[356,357],120.0505,27.66628,{"lat":357,"lon":356},[360],{"name":361,"role":36,"phone":11,"phoneExt":11,"email":11},"Haibo Lin",{"facility":363,"status":11,"city":364,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":365,"geoPoint":369,"contacts":370},"Shaoxing People's Hospital","Shaoxing",{"type":46,"coordinates":366},[367,368],120.57864,30.00237,{"lat":368,"lon":367},[371],{"name":372,"role":36,"phone":11,"phoneExt":11,"email":11},"Dihua Huang",{"facility":374,"status":11,"city":375,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":376,"geoPoint":380,"contacts":381},"Shengjing Hospital of China Medical University","Shenyang",{"type":46,"coordinates":377},[378,379],123.43278,41.79222,{"lat":379,"lon":378},[382],{"name":383,"role":36,"phone":11,"phoneExt":11,"email":11},"Ying Xin",{"facility":385,"status":11,"city":386,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":387,"geoPoint":391,"contacts":392},"Shenzhen Children's Hospital","Shenzhen",{"type":46,"coordinates":388},[389,390],114.0683,22.54554,{"lat":390,"lon":389},[393],{"name":394,"role":36,"phone":11,"phoneExt":11,"email":11},"Zhe Su",{"facility":396,"status":11,"city":397,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":398,"geoPoint":402,"contacts":403},"West China Second University Hospital, Sichuan University","Sichuan",{"type":46,"coordinates":399},[400,401],105.48032,35.1221,{"lat":401,"lon":400},[404],{"name":405,"role":36,"phone":11,"phoneExt":11,"email":11},"Jin Wu",{"facility":407,"status":11,"city":408,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":409,"geoPoint":413,"contacts":414},"Children's Hospital of Soochow University","Suzhou",{"type":46,"coordinates":410},[411,412],120.59538,31.30408,{"lat":412,"lon":411},[415],{"name":416,"role":36,"phone":11,"phoneExt":11,"email":11},"Fengyun Wang",{"facility":418,"status":11,"city":419,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":420,"geoPoint":424,"contacts":425},"Taizhou First People's Hospital","Taizhou",{"type":46,"coordinates":421},[422,423],119.90812,32.49069,{"lat":423,"lon":422},[426],{"name":427,"role":36,"phone":11,"phoneExt":11,"email":11},"Xiaoming Ying",{"facility":429,"status":11,"city":419,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":430,"geoPoint":432,"contacts":433},"Taizhou People's Hospital",{"type":46,"coordinates":431},[422,423],{"lat":423,"lon":422},[434],{"name":435,"role":36,"phone":11,"phoneExt":11,"email":11},"Shufang Yang",{"facility":437,"status":11,"city":438,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":439,"geoPoint":443,"contacts":444},"Tangshan Maternal and Child Health Hospital","Tangshan",{"type":46,"coordinates":440},[441,442],118.18319,39.64381,{"lat":442,"lon":441},[445],{"name":446,"role":36,"phone":11,"phoneExt":11,"email":11},"Lanying Wang",{"facility":448,"status":11,"city":449,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":450,"geoPoint":454,"contacts":455},"The First Affiliated Hospital of Wenzhou Medical University","Wenzhou",{"type":46,"coordinates":451},[452,453],120.66682,27.99942,{"lat":453,"lon":452},[456],{"name":457,"role":36,"phone":11,"phoneExt":11,"email":11},"Hong Zhu",{"facility":459,"status":11,"city":460,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":461,"geoPoint":465,"contacts":466},"Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology","Wuhan",{"type":46,"coordinates":462},[463,464],114.26667,30.58333,{"lat":464,"lon":463},[467],{"name":31,"role":36,"phone":11,"phoneExt":11,"email":11},{"facility":469,"status":11,"city":460,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":470,"geoPoint":472,"contacts":473},"Wuhan Children's Hospital",{"type":46,"coordinates":471},[463,464],{"lat":464,"lon":463},[474],{"name":475,"role":36,"phone":11,"phoneExt":11,"email":11},"Hui Yao",{"facility":477,"status":11,"city":478,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":479,"geoPoint":483,"contacts":484},"Affiliated Hospital of Jiangnan University","Wuxi",{"type":46,"coordinates":480},[481,482],120.28857,31.56887,{"lat":482,"lon":481},[485],{"name":486,"role":36,"phone":11,"phoneExt":11,"email":11},"Yaping Ma",{"facility":488,"status":11,"city":489,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":490,"geoPoint":494,"contacts":495},"The Second Affiliated Hospital of Xi'an Jiaotong University","Xi'an",{"type":46,"coordinates":491},[492,493],108.92861,34.25833,{"lat":493,"lon":492},[496],{"name":497,"role":36,"phone":11,"phoneExt":11,"email":11},"Erdi Xu",{"facility":499,"status":11,"city":500,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":501,"geoPoint":505,"contacts":506},"Xiamen Maternal and Child Health Hospital","Xiamen",{"type":46,"coordinates":502},[503,504],118.08187,24.47979,{"lat":504,"lon":503},[507],{"name":508,"role":36,"phone":11,"phoneExt":11,"email":11},"Xiaoqing Yang",{"facility":510,"status":11,"city":511,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":512,"geoPoint":516,"contacts":517},"Xiangyang First People's Hospital","Xiangyang",{"type":46,"coordinates":513},[514,515],112.14479,32.0422,{"lat":515,"lon":514},[518],{"name":519,"role":36,"phone":11,"phoneExt":11,"email":11},"Xi Yang",{"facility":521,"status":11,"city":522,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":523,"geoPoint":527,"contacts":528},"The First Affiliated Hospital of Xinjiang Medical University","Xinjiang",{"type":46,"coordinates":524},[525,526],120.44325,30.46809,{"lat":526,"lon":525},[529],{"name":530,"role":36,"phone":11,"phoneExt":11,"email":11},"Mirigul Maimaiti",{"facility":532,"status":11,"city":533,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":534,"geoPoint":538,"contacts":539},"Yibin Second People's Hospital","Yibin",{"type":46,"coordinates":535},[536,537],104.63994,28.7593,{"lat":537,"lon":536},[540],{"name":541,"role":36,"phone":11,"phoneExt":11,"email":11},"Lan Yao",{"facility":543,"status":11,"city":544,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":545,"geoPoint":549,"contacts":550},"Henan Children's Hospital Zhengzhou Children's Hospital","Zhengzhou",{"type":46,"coordinates":546},[547,548],113.64861,34.75778,{"lat":548,"lon":547},[551],{"name":552,"role":36,"phone":11,"phoneExt":11,"email":11},"Haiyan Wei",{"facility":554,"status":11,"city":555,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":556,"geoPoint":560,"contacts":561},"Zibo Central Hospital","Zibo",{"type":46,"coordinates":557},[558,559],118.06333,36.79056,{"lat":559,"lon":558},[562],{"name":563,"role":36,"phone":11,"phoneExt":11,"email":11},"Xiaodong Zhao",{"type":565,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100640722","phase-3-the-efficacy-and-safety-of-inpegsomatropin-injection-in-children-with-turner-syndrome-ts-and-short-stature-100640722",false,"NCT07614152","The Efficacy and Safety of Inpegsomatropin Injection in Children With Turner Syndrome (TS) and Short Stature","Multicenter, Randomized, Open-Label, Positive-Controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of Inpegsomatropin Injection Versus Givopegsomatropin Solution Injection in the Treatment of Short Stature in Children With Turner Syndrome.","Inclusion Criteria:\n\n* Prepubertal girls at Tanner stage I, with age ≥ 2 years and \\\u003C 12 years at the time of informed consent signature.\n* With clinical manifestations of Turner syndrome and a confirmed diagnosis of Turner syndrome based on peripheral blood karyotype analysis (karyotype analysis of at least 30 metaphase cells).\n* At screening, bone age is delayed relative to chronological age or advanced by no more than 1 year (i.e., bone age - chronological age ≤ 1 year).\n* At screening, height is below -2 standard deviations (-2SD) of the mean for age and gender; height reference is shown in Appendix 1.\n* No prior systematic pharmacological growth-promoting treatment (continuous use for ≥ 1 month), including but not limited to growth hormone, insulin-like growth factor 1 (IGF-1), etc.\n* Thyroid hormone replacement therapy (if applicable) received prior to randomization should be maintained on a stable regimen for at least 4 weeks.\n* The legal guardian understands and signs the informed consent form; participants aged ≥ 8 years shall also sign the informed consent form. For participants aged under 8 years who are capable of expressing assent, their assent shall be clearly documented.\n\nExclusion Criteria:\n\n* Subjects with closed epiphyses.\n* Patients with Turner syndrome carrying Y chromosome or Y-chromosome-derived fragments and without gonadectomy.\n* Other types of growth and development abnormalities, including but not limited to growth hormone deficiency (GHD), Noonan syndrome, Prader-Willi syndrome, and growth retardation caused by malnutrition.\n* Participation in any other clinical trial within 3 months prior to screening with pharmacological or non-pharmacological intervention received.\n* Inhaled glucocorticoids used continuously for more than 2 weeks, or oral\u002Fintravenous glucocorticoids used continuously for more than 1 week within 3 months prior to screening.\n* Receiving other treatments that may affect growth, including but not limited to methylphenidate, sex hormones, gonadotropin-releasing hormone analogs, aromatase inhibitors, anabolic agents, etc.\n* Abnormal liver and renal function at screening (ALT \\> 2 times the upper limit of normal; Cr \\> upper limit of normal).\n* Subjects with abnormal glucose metabolism, including: a. Diagnosed diabetes mellitus; b. Fasting blood glucose ≥ 6.1 mmol\u002FL on two consecutive measurements; c. Glycated hemoglobin (HbA1c) ≥ 6.5%; d. Impaired glucose tolerance judged by the investigator as unsuitable for participation in this study.\n* Presence of chronic infectious diseases judged by the investigator to interfere with study participation, such as chronic hepatitis B.\n* Subjects with systemic chronic diseases, such as chronic kidney disease, severe cardiovascular diseases (e.g., aortic dissection, uncontrolled hypertension), psychiatric and psychological disorders.\n* Subjects with severe congenital skeletal dysplasia; or those with scoliosis \\> 20°, significant kyphosis, claudication, or a prior diagnosis of slipped capital femoral epiphysis.\n* Subjects with a prior history of intracranial hypertension.\n* Subjects with a history of malignant tumor or current active malignant tumor, including intracranial tumors.\n* Known hypersensitivity to growth hormone or its excipients.\n* Subjects with celiac disease who have not maintained a gluten-free diet within 12 months prior to screening.\n* Any other conditions deemed inappropriate for enrollment in this clinical trial by the investigator.","FEMALE","2 Years","12 Years",{"count":577,"type":578},84,"ESTIMATED","INTERVENTIONAL",[581],"PHASE3","This is a multicenter, randomized, open-label, positive-controlled phase III confirmatory clinical study. A total of 84 children with short stature due to Turner Syndrome (TS) are planned to be enrolled. Stratified by age and karyotype, subjects will be randomized at a 1:1 ratio to either the test group or the positive control group with continuous treatment for 52 weeks. The study aims to compare the efficacy and safety of Inpegsomatropin-Injection versus Givopegsomatropin Solution Injection in children with TS-related short stature, so as to provide evidence for the new indication application of the investigational drug.",[584],"Turner Syndrome",[586,26],"Inpegsomatropin Injection","NOT_YET_RECRUITING","2026-05-28",{"date":590,"type":591},"2026-06-02","ACTUAL",{"date":593,"type":578},"2026-06-15",{"date":595,"type":578},"2030-02-28",{"name":5,"class":6},51]