[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100422019":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":119,"collaborators":18,"id":121,"slug":122,"hasResults":123,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":127,"eligibilityCriteria":128,"healthyVolunteers":123,"sex":129,"minAge":130,"maxAge":18,"enrollmentInfo":131,"targetDuration":18,"studyType":134,"phases":135,"briefSummary":137,"conditions":138,"keywords":140,"overallStatus":56,"whyStopped":18,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":153},{"fullName":5,"class":6},"Hôpital NOVO","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Vitamin D","EXPERIMENTAL","During preoperative visit (Month -2) patients will receive a cholecalciferol supplementation added to a fruit juice.",[13],"Drug: Vitamin D",{"label":15,"type":16,"description":17,"interventionNames":18},"Fruit juice","NO_INTERVENTION","During preoperative visit (Month -2) patients will receive only fruit juice.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Patients will receive a cholecalciferol supplementation added to a fruit juice.",[9],[25],"Treatment",[27],{"name":28,"affiliation":5,"role":29},"Dr Khaled AL TABAA","PRINCIPAL_INVESTIGATOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":18,"email":35},"Maryline Delattre","CONTACT","+33 1 30 75 41 31","maryline.delattre@ght-novo.fr",{"name":37,"role":33,"phone":38,"phoneExt":18,"email":39},"Veronique Da Costa","+33 1 30 75 50 69","veronique.dacosta@ght-novo.fr",[41,54,69,83,92,106],{"facility":42,"status":43,"city":44,"state":18,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":18},"Department of General, Digestive and Endocrine 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72","kevin.buquet@ght85.fr",{"facility":84,"status":43,"city":85,"state":18,"zip":86,"country":46,"countryCode":47,"cosmosGeoPoint":87,"geoPoint":91,"contacts":18},"Hospital Lariboisière, Paris X","Paris","75010",{"type":49,"coordinates":88},[89,90],2.3488,48.85341,{"lat":90,"lon":89},{"facility":93,"status":56,"city":94,"state":18,"zip":95,"country":46,"countryCode":47,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"Hospital Poissy\u002FSaint-Germain","Poissy","78300",{"type":49,"coordinates":97},[98,99],2.04952,48.92902,{"lat":99,"lon":98},[102],{"name":103,"role":33,"phone":104,"phoneExt":18,"email":105},"Pr Didier SIMON","++33 1 39 27 42 69","didier.simon@ght-yvelinesnord.fr",{"facility":107,"status":56,"city":108,"state":18,"zip":109,"country":46,"countryCode":47,"cosmosGeoPoint":110,"geoPoint":114,"contacts":115},"Hospital René Dubos,","Pontoise","95300",{"type":49,"coordinates":111},[112,113],2.1,49.05,{"lat":113,"lon":112},[116],{"name":28,"role":33,"phone":117,"phoneExt":18,"email":118},"+33 1 30 75 71 51","khaled.altabaa@ght-novo.fr",{"type":120,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100422019","phase-3-total-post-thyroidectomy-hypocalcemia-after-preoperative-cholecalciferol-supplementation-100422019",false,"NCT04775381","Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation","Study of Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation","CAVITHY","Inclusion Criteria:\n\n* Patient ≥ 18 years old\n* Patient shall be operated on for a total thyroidectomy in one time for any indication\n* Written informed consent (IC) obtained\n* Patients with affiliation to the social security system\n\nExclusion Criteria:\n\n• Medical history of : Thyroid or parathyroid surgery Hyperparathyroidism Granulomatosis flare-up\n\n* Hypocalcemia, hypercalcemia\u002F hypercalciuria, or symptom of Hypocalcemia, hypercalcemia\u002F hypercalciuria, not due to thyroid pathologies\n* Chronic kidney disease grade ≥4\n* Severe liver failure\n* 25OHD supplementation within last 3 months before surgery\n* Malabsorption syndrome\n* Known hypersensitivity to vitamin D\n* Medical history of calcic lithiasis\n* Pregnant women\n* Vulnerable populations (guardianship or trusteeship)\n* Allergies to one of the components of the fruit juice","ALL","18 Years",{"count":132,"type":133},200,"ESTIMATED","INTERVENTIONAL",[136],"PHASE3","This prospective study evalue the inflence of pre operative vit D3 administration on post operative hypocalcemia in patients undergoing Total thyroidectomy",[139],"Hypocalcemia",[141,142,143],"Total thyroidectomy","hypocalcemia","cholecalciferol supplementation","2025-01-17",{"date":146,"type":147},"2025-01-20","ACTUAL",{"date":149,"type":147},"2021-06-30",{"date":151,"type":133},"2026-03",{"name":5,"class":6},6]