[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556002":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":26,"responsibleParty":44,"collaborators":46,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":59,"maxAge":26,"enrollmentInfo":60,"targetDuration":26,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":76,"whyStopped":26,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":26},{"fullName":5,"class":6},"London School of Hygiene and Tropical Medicine","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Tranexamic acid (TXA)","EXPERIMENTAL","Tranexamic acid 1 gram (2x 500 mg) orally taken three times a day from the first to the last day of the menstrual period for up to 5 days, for 3 successive periods.",[13],"Drug: Tranexamic Acid 500 MG",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Matched placebo tablets taken three times a day from the first to the last day of the menstrual period for up to 5 days, for 3 successive periods.",[19],"Other: Matched placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Tranexamic Acid 500 MG","Tablets",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Matched placebo","Matched placebo tablets (inactive ingredients only, including microcrystalline cellulose, magnesium stearate BP and lactose)",[15],[32],{"name":33,"affiliation":34,"role":35},"Dr Sima Berendes","London School of Hygiene and Tropical Medicine (Clinical Trials Unit)","STUDY_DIRECTOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+44 (0)20 7958 8161","woman3@lshtm.ac.uk",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":26},"Professor Ian Roberts","+44 (0)20 7958 8128",{"type":45,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[47],{"name":48,"class":49},"The Jon Moulton Charity Trust","UNKNOWN","100556002","phase-3-tranexamic-acid-for-anaemia-trial-100556002",false,"NCT06519422","Tranexamic Acid for Anaemia Trial","The Effects of Tranexamic Acid on Anaemia, Menstrual Health and the Wellbeing of Women: an International Randomised, Placebo-controlled Trial Among Menstruating Women With Anaemia","WOMAN-3","Inclusion Criteria:\n\n* Adult women (aged 18 years and older)\n* Having menstrual periods every 21 to 38 days that last 2 to 9 days\n* Having anaemia (Hb \\\u003C 120 g\u002FL) according to point-of-care finger prick screening test\n* Willing to provide informed consent and able to attend study visits during the trial period\n\n(Individuals with known thalassaemia are eligible to participate and take the trial treatment but will not receive standard of care iron supplementation. They will continue to receive their standard care.)\n\nExclusion Criteria:\n\n* Planning to get pregnant during trial period\n* Already taking TXA\n* Known to have contraindications to TXA treatment (including allergy to TXA or its excipients, renal impairment, active thromboembolic disease, history of venous or arterial thrombosis, history of convulsion.)","FEMALE","18 Years",{"count":61,"type":62},4000,"ESTIMATED","INTERVENTIONAL",[65],"PHASE3","Anaemia is a common health problem in women. It is often due to iron deficiency. Anaemia is a particular problem during pregnancy and is bad for the mother and baby. It is best to treat anaemia in young women well before they get pregnant. Doctors treat anaemia with iron and vitamins. But some people get side effects when taking iron tablets and so they stop taking them. Heavy menstrual periods are a common cause of iron deficiency and even if women do take iron, because they lose so much iron in their periods, they still become iron deficient. Tranexamic acid (TXA) is a medicine used to treat heavy periods. The investigators of this study would like to find out if taking TXA with the usual iron and vitamin supplements is better at treating anaemia than taking iron and vitamin supplements alone. (Lay Summary)",[68],"Anemia",[70,71,72,73,74,75],"Tranexamic acid","Antifibrinolytic","Anaemia","Menstrual health","Menstruation","Bleeding","NOT_YET_RECRUITING","2024-07-19",{"date":79,"type":80},"2024-07-25","ACTUAL",{"date":82,"type":62},"2025-09",{"date":84,"type":62},"2028-09",{"name":5,"class":6}]