[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559049":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":24,"locations":34,"responsibleParty":51,"collaborators":53,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":18,"enrollmentInfo":65,"targetDuration":18,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":77,"overallStatus":81,"whyStopped":18,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"The George Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Atorvastatin group","EXPERIMENTAL","On the basis of routine treatment for aneurysmal subarachnoid hemorrhage, atorvastatin was administered at an ultra early stage at a dose of 40mg\u002Fd for 14 consecutive days",[13],"Drug: Atorvastatin",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional treatment group","NO_INTERVENTION","Conventional treatment for aneurysmal subarachnoid hemorrhage typically includes measures such as blood pressure control, hemostasis, reduction of intracranial pressure, prevention of complications, and, when deemed necessary based on the patient's condition, surgical intervention. No specific interventions are applied unless warranted.",null,[20],{"type":21,"name":22,"description":11,"armGroupLabels":23,"otherNames":18},"DRUG","Atorvastatin",[9],[25,30],{"name":26,"role":27,"phone":28,"phoneExt":18,"email":29},"Rongcai Jiang","CONTACT","+86 136 7211 6556","jiang116216@163.com",{"name":31,"role":27,"phone":32,"phoneExt":18,"email":33},"Tao Liu","61-466068193","liu_t2019@163.com",[35],{"facility":36,"status":18,"city":37,"state":18,"zip":18,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Tianjin Medical University General Hospital","Tianjin","China","CN",{"type":41,"coordinates":42},"Point",[43,44],117.17667,39.14222,{"lat":44,"lon":43},[47],{"name":48,"role":27,"phone":49,"phoneExt":18,"email":50},"Zhihao Zhao","+86 13633627965","zzhtmu@163.com",{"type":52,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[54],{"name":36,"class":6},"100559049","phase-3-ultra-early-statin-in-patients-with-aneurysmal-subarachnoid-hemorrhage-ue-star-100559049",false,"NCT06559072","Ultra-early STatin in Patients With Aneurysmal subaRachnoid Hemorrhage (Ue-STAR)","Ultra-early STatin in Patients With Aneurysmal subaRachnoid Hemorrhage (Ue-STAR): a Randomized Controlled Trial","Ue-STAR","Inclusion Criteria:\n\n1. Male or female; Aged ≥18 years\n2. Signs and symptoms presumed aneurysmal subarachnoid hemorrhage, confirmed by radiological evidence\n3. Treatment within 6 h after symptom onset\n\nExclusion Criteria:\n\n1. Treatment with statin prior SAH\n2. Non-aSAH (e.g. traumatic subarachnoid hemorrhage, arteriovenous malformation)\n3. Treatment \\> 6 h after symptom onset\n4. Allergy to statin medications or presence of severe adverse reactions such as abnormal liver function or rhabdomyolysis\n5. Evidence of irreversible brain damage or expected death within 7 days\n6. Known severe liver or kidney disease\n7. Non-compliance with follow-up\n8. Pregnant or breastfeeding\n9. History of severe cranial or psychiatric illness\n10. Concomitant serious systemic disease\n11. Patients with malignant tumors\n12. Currently participating in another clinical trial\n13. Considered unsuitable for the clinical trial by clinical physicians or researchers","ALL","18 Years",{"count":66,"type":67},522,"ESTIMATED","INTERVENTIONAL",[70],"PHASE3","A researcher-initiated and conducted multicenter, randomized controlled trial aimed at evaluating the efficacy and safety of ultra-early statin therapy in the treatment of acute aneurysmal subarachnoid hemorrhage (aSAH).",[73,74,75,76],"Subarachnoid Hemorrhage","Subarachnoid Hemorrhage, Aneurysmal","Aneurysmal Subarachnoid Hemorrhage","Hemorrhage, Aneurysmal Subarachnoid",[78,79,80],"aneurysmal subarachnoid hemorrhage","atorvastatin","Atorvastatin Calcium","NOT_YET_RECRUITING","2024-09-01",{"date":84,"type":85},"2024-09-05","ACTUAL",{"date":82,"type":67},{"date":88,"type":67},"2026-09-01",{"name":5,"class":6},1]