[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100508925":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":35,"responsibleParty":61,"collaborators":25,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":25,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":25,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Tulane University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Immediate intervention arm","ACTIVE_COMPARATOR","Immediate angiography will be performed within 24 hours of enrollment. Omnipaque contrast will be administered. Serum creatinine will be collected on enrollment, within 6 hours before coronary angiography, and at 24h, 48h and 1-week after the angiography, as expected in common practice. Pre- and post-hydration administration will be at the discretion of the treating physician. In case percutaneous coronary intervention is indicated it will be schedule for 7 days after angiography.",[13],"Procedure: Angiography",{"label":15,"type":16,"description":17,"interventionNames":18},"Delayed intervention arm","PLACEBO_COMPARATOR","Delayed angiography will be performed after kidney function stabilizes.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Angiography","Coronary angiography with less than 20cc of contrast materials",[15,9],null,[27],{"name":28,"affiliation":5,"role":29},"Zach Rozenbaum, MD","PRINCIPAL_INVESTIGATOR",[31],{"name":28,"role":32,"phone":33,"phoneExt":25,"email":34},"CONTACT","504-988-5493","zrozenbaum@tulane.edu",[36,53],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Tulane University Medical Center","RECRUITING","New Orleans","Louisiana","70112","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-90.07507,29.95465,{"lat":48,"lon":47},[51,52],{"name":28,"role":32,"phone":33,"phoneExt":25,"email":34},{"name":28,"role":29,"phone":25,"phoneExt":25,"email":25},{"facility":54,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":55,"geoPoint":57,"contacts":58},"University Medical Center",{"type":45,"coordinates":56},[47,48],{"lat":48,"lon":47},[59,60],{"name":28,"role":32,"phone":33,"phoneExt":25,"email":34},{"name":28,"role":29,"phone":25,"phoneExt":25,"email":25},{"type":62,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100508925","phase-3-ultra-low-contrast-angiography-in-aki-100508925",false,"NCT05906758","Ultra-Low Contrast Angiography in AKI","Randomized Controlled Trial of Ultra-Low Contrast Coronary Angiography During Acute Kidney Injury (AKI)","Inclusion Criteria:\n\n* Hospitalized patients who have AKI at admission or who develop AKI during admission and require invasive coronary angiography will be included in the trial.\n\nExclusion Criteria:\n\n* Stabilized renal function manifested by unchanged or downtrending serum creatinine during a 24-hour period prior to enrollment.\n* Contraindication for invasive coronary angiography other than AKI.\n* Percutaneous coronary intervention is indicated and cannot be postponed by 7 days.\n* Need for renal replacement therapy before coronary angiography or planned renal replacement therapy after coronary angiography (if premeditated before coronary angiography).\n* Administration of intravascular contrast media during 7 days prior to the coronary angiography or within 6 days after coronary angiography.\n* Pregnant patients, prisoners, cognitively impaired subjects, age below 18 years, unable or unwilling to provide informed consent.","ALL","18 Years","100 Years",{"count":74,"type":75},32,"ESTIMATED","INTERVENTIONAL",[78],"PHASE3","The aim of this study is to evaluate the safety of ultra-low contrast coronary angiography in patients with pre-existing acute kidney injury.",[81],"Acute Kidney Injury",[83,84],"Coronary angiography","Ultra low contrast","2026-05-13",{"date":87,"type":88},"2026-05-18","ACTUAL",{"date":90,"type":88},"2025-09-05",{"date":92,"type":75},"2027-12",{"name":5,"class":6},2]