[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596217":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":34,"responsibleParty":116,"collaborators":20,"id":118,"slug":119,"hasResults":120,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":20,"eligibilityCriteria":124,"healthyVolunteers":120,"sex":125,"minAge":126,"maxAge":20,"enrollmentInfo":127,"targetDuration":20,"studyType":130,"phases":131,"briefSummary":133,"conditions":134,"keywords":146,"overallStatus":37,"whyStopped":20,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":162},{"fullName":5,"class":6},"Memorial Sloan Kettering Cancer Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Hormone-receptor positive breast cancer participants","EXPERIMENTAL","Participants will have a diagnosis of Stage 0-III Hormone-receptor positive breast cancer",[13],"Drug: Revaree Plus",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Revaree Plus","Revaree Plus is a hyaluronic acid vaginal suppository",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Shari Goldfarb, MD","PRINCIPAL_INVESTIGATOR",[26,30],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},"CONTACT","646-888-5080","goldfars@mskcc.org",{"name":31,"role":27,"phone":32,"phoneExt":20,"email":33},"Jeanne Carter, PhD","646-888-5076","carterj@mskcc.org",[35,51,62,73,85,96,105],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Memorial Sloan Kettering Basking Ridge (Consent Only)","RECRUITING","Basking Ridge","New Jersey","07920","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-74.54932,40.70621,{"lat":47,"lon":46},[50],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":20},{"facility":52,"status":37,"city":53,"state":39,"zip":54,"country":41,"countryCode":42,"cosmosGeoPoint":55,"geoPoint":59,"contacts":60},"Memorial Sloan Kettering Monmouth (Consent Only)","Middletown","07748",{"type":44,"coordinates":56},[57,58],-74.11709,40.39428,{"lat":58,"lon":57},[61],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":20},{"facility":63,"status":37,"city":64,"state":39,"zip":65,"country":41,"countryCode":42,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"Memorial Sloan Kettering Bergen (Consent Only)","Montvale","07645",{"type":44,"coordinates":67},[68,69],-74.02292,41.04676,{"lat":69,"lon":68},[72],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":20},{"facility":74,"status":37,"city":75,"state":76,"zip":77,"country":41,"countryCode":42,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Memorial Sloan Kettering Cancer Center Suffolk-Commack (Consent Only)","Commack","New York","11725",{"type":44,"coordinates":79},[80,81],-73.29289,40.84288,{"lat":81,"lon":80},[84],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":20},{"facility":86,"status":37,"city":87,"state":76,"zip":88,"country":41,"countryCode":42,"cosmosGeoPoint":89,"geoPoint":93,"contacts":94},"Memorial Sloan Kettering Westchester (Consent Only)","Harrison","10604",{"type":44,"coordinates":90},[91,92],-73.71263,40.96899,{"lat":92,"lon":91},[95],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":20},{"facility":5,"status":37,"city":76,"state":76,"zip":97,"country":41,"countryCode":42,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"10021",{"type":44,"coordinates":99},[100,101],-74.00597,40.71427,{"lat":101,"lon":100},[104],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":20},{"facility":106,"status":37,"city":107,"state":76,"zip":108,"country":41,"countryCode":42,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Memorial Sloan Kettering Nassau (Consent Only)","Uniondale","11553",{"type":44,"coordinates":110},[111,112],-73.59291,40.70038,{"lat":112,"lon":111},[115],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":20},{"type":117,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100596217","phase-4-a-study-of-revaree-plus-in-people-with-breast-cancer-100596217",false,"NCT07042581","A Study of Revaree Plus in People With Breast Cancer","Evaluation of Revaree Plus in Women With Breast Cancer","Inclusion Criteria:\n\n* ≥18 years of age at the time of signing informed consent.\n* Stage 0-3 hormone-receptor positive breast cancer confirmed at MSKCC\n* Able to complete study questionnaires in English or Spanish\n* Breast cancer patients must have completed primary therapy (surgery, and\u002For chemotherapy, and\u002For radiation therapy) or currently on maintenance therapy\n* Currently on an aromatase inhibitor or tamoxifen or Selective Estrogen Receptor Modulators (SERM)\n* Currently have no clinical evidence of disease\n* Reporting being bothered by vaginal symptoms of estrogen deprivation (i.e., vaginal dryness, dyspareunia, or discomfort \\[pain with intercourse or examination\\])\n* A total score of 4 or greater in VAS\n* Without history of other cancers (excluding non-melanoma skin cancer)\n* Must sign an informed consent indicating that the participant understands the purpose of, and procedures required for the study and is willing to participate in the study\n\nExclusion Criteria:\n\n* Inability to provide informed consent\n* Vaginal bleeding of unknown etiology within 12 months of study entry\n* Currently taking hormone replacement therapy \\[local or systemic\\] (Patients must discontinue for 4 weeks in order to be eligible prior to study enrollment)\n* Existing use of external estrogens or nonhormonal moisturizers (Patients must discontinue for 4 weeks in order to be eligible prior to study enrollment)\n* No known allergies to any ingredients in 10mg HLA suppository","FEMALE","18 Years",{"count":128,"type":129},60,"ESTIMATED","INTERVENTIONAL",[132],"PHASE4","The purpose of this study is to find out whether Revaree Plus is effective at improving vaginal health for people who are having symptoms of vaginal dryness during breast cancer treatment.",[135,136,137,138,139,140,141,142,143,144,145],"Breast Cancer","Stage 0 Breast Cancer","Stage I Breast Cancer","Stage II Breast Cancer","Stage III Breast Cancer","Stage 0 Breast Carcinoma","Stage II Breast Carcinoma","Stage III Breast Carcinoma","Hormone-receptor-positive Breast Cancer","Hormone Receptor Positive Breast Carcinoma","Hormone Receptor Positive Malignant Neoplasm of Breast",[135,136,137,138,139,147,148,149,150,151,152,5],"Stage 0 hormone receptor positive breast cancer","Stage I hormone receptor positive breast cancer","Stage II hormone receptor positive breast cancer","Stage III hormone receptor positive breast cancer","Revaree","24-374","2026-02-04",{"date":155,"type":156},"2026-02-06","ACTUAL",{"date":158,"type":156},"2025-06-20",{"date":160,"type":129},"2029-06-20",{"name":5,"class":6},7]