[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622843":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":23,"centralContacts":34,"locations":40,"responsibleParty":52,"collaborators":23,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":23,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":78,"whyStopped":23,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"calcium hydroxide (Ca(OH)2)","ACTIVE_COMPARATOR","intracanal medicament in infected root canal",[13],"Drug: Calcium Hydroxide (Ca(OH)2)",{"label":15,"type":16,"description":17,"interventionNames":18},"Chitosan nano particles (CNPs)","EXPERIMENTAL","intracanal medication in infected root canal",[19],"Drug: chitosan nanoparticles gel",{"label":21,"type":22,"description":23,"interventionNames":23},"control","NO_INTERVENTION",null,[25,30],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":23},"DRUG","Calcium Hydroxide (Ca(OH)2)","Non setting calcium hydroxide intracanal medicament is injected through the root canal for two weeks",[9],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":23},"chitosan nanoparticles gel","Nano chitosan gel is injected through the root canal as an intracanal medicament for two weeks",[15],[35],{"name":36,"role":37,"phone":38,"phoneExt":23,"email":39},"Rana M Nagdy, MSc","CONTACT","+201006224327","Rananagdy@dent.asu.edu.eg",[41],{"facility":42,"status":23,"city":43,"state":23,"zip":23,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":23},"Faculty of Dentistry Ain Shams University","Cairo","Egypt","EG",{"type":47,"coordinates":48},"Point",[49,50],31.24967,30.06263,{"lat":50,"lon":49},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Rana mohamed mustafa nagdy","Dentist","100622843","phase-4-antibacterial-effect-of-two-different-intracanal-medicaments-and-their-effect-on-post-operative-pain-100622843",false,"NCT07388888","Antibacterial Effect of Two Different Intracanal Medicaments and Their Effect on Post-operative Pain","Comparative Evaluation of Anti-Bacterial Efficacy Of Two Different Intracanal-Medicaments and Their Effect On Post-Operative Pain Level (A Randomized Clinical Trial)","Ca(OH)2 - CNPs","Inclusion Criteria:\n\n* free medical history,\n* mature infected permanent single rooted teeth diagnosed clinically and radiographically with adequate coronal structure for proper isolation, temporization and restoration.\n\nExclusion Criteria:\n\n* Patients who are not included in the age range of the study or having a systemic condition.\n* Teeth with severe fractures or resorption or periodontally compromised.","ALL","18 Years","50 Years",{"count":68,"type":69},52,"ESTIMATED","INTERVENTIONAL",[72],"PHASE4","Evaluation of antibacterial effect of two different intracanal medicaments on bacterial load in infected mature permanent teeth and their effect on post-operative pain level.",[75],"Pulp Necrosis",[77],"effect of two intracanal medicaments on bacterial load and post operative pain level in mature teeth with necrotic pulp","NOT_YET_RECRUITING","2026-01-28",{"date":81,"type":82},"2026-02-05","ACTUAL",{"date":84,"type":69},"2026-02",{"date":86,"type":69},"2027-04",{"name":5,"class":6},1]