[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605562":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":25,"locations":34,"responsibleParty":109,"collaborators":25,"id":112,"slug":113,"hasResults":114,"nctId":115,"briefTitle":116,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":114,"sex":119,"minAge":120,"maxAge":25,"enrollmentInfo":121,"targetDuration":25,"studyType":124,"phases":125,"briefSummary":127,"conditions":128,"keywords":130,"overallStatus":80,"whyStopped":25,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":141},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Doxycycline group","ACTIVE_COMPARATOR","Subjects hospitalized for community acquired pneumonia will receive standard of care treatment with Doxycycline",[13],"Drug: Doxycycline",{"label":15,"type":10,"description":16,"interventionNames":17},"Azithromycin group","Subjects hospitalized for community acquired pneumonia will receive standard of care treatment with Azithromycin",[18],"Drug: Azithromycin",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Doxycycline","Subjects will receive Doxycycline (orally or intravenously) in combination with beta-lactam therapy within 12 hours of hospital admission. Treatment duration will be 5-7 days.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Azithromycin","Subjects will receive Azithromycin (orally or intravenously) in combination with beta-lactam therapy within 12 hours of hospital admission. Treatment duration will be 5-7 days.",[15],[31],{"name":32,"affiliation":5,"role":33},"Yewande Odeyemi","PRINCIPAL_INVESTIGATOR",[35,52,65,78,96],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Mayo Clinic in Arizona","NOT_YET_RECRUITING","Scottsdale","Arizona","85259","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-111.89903,33.50921,{"lat":47,"lon":46},[50],{"name":51,"role":33,"phone":25,"phoneExt":25,"email":25},"Cyril Varghese",{"facility":53,"status":37,"city":54,"state":55,"zip":56,"country":41,"countryCode":42,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Mayo Clinic in Florida","Jacksonville","Florida","32224",{"type":44,"coordinates":58},[59,60],-81.65565,30.33218,{"lat":60,"lon":59},[63],{"name":64,"role":33,"phone":25,"phoneExt":25,"email":25},"Swetha Reddy",{"facility":66,"status":37,"city":67,"state":68,"zip":69,"country":41,"countryCode":42,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Mayo Clinic Health System-Mankato","Mankato","Minnesota","56001",{"type":44,"coordinates":71},[72,73],-94.00915,44.15906,{"lat":73,"lon":72},[76],{"name":77,"role":33,"phone":25,"phoneExt":25,"email":25},"Mohamad El Labban",{"facility":79,"status":80,"city":81,"state":68,"zip":82,"country":41,"countryCode":42,"cosmosGeoPoint":83,"geoPoint":87,"contacts":88},"Mayo Clinic in Rochester","RECRUITING","Rochester","55905",{"type":44,"coordinates":84},[85,86],-92.4699,44.02163,{"lat":86,"lon":85},[89,94],{"name":90,"role":91,"phone":92,"phoneExt":25,"email":93},"Amy Amsbaugh","CONTACT","507-538-7538","amsbaugh.amy@mayo.edu",{"name":95,"role":33,"phone":25,"phoneExt":25,"email":25},"Yewande Efunpeju Odeyemi",{"facility":97,"status":37,"city":98,"state":99,"zip":100,"country":41,"countryCode":42,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Mayo Clinic Health System-La Crosse","La Crosse","Wisconsin","54601",{"type":44,"coordinates":102},[103,104],-91.23958,43.80136,{"lat":104,"lon":103},[107],{"name":108,"role":33,"phone":25,"phoneExt":25,"email":25},"Melissa K Myers",{"type":33,"investigatorFullName":110,"investigatorTitle":111,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Yewande Odeyemi, MD","Principal Investigator","100605562","phase-4-azithromycin-versus-doxycycline-in-hospitalized-adult-patients-with-community-acquired-pneumonia-treated-with-beta-lactams-100605562",false,"NCT07164131","Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lactams","AD-CAP","Inclusion Criteria:\n\n• All adult patients (\\>18 years old) admitted with CAP and receiving a beta-lactam antibiotic plus a form of atypical coverage (azithromycin or doxycycline) in the ED within 12 hours of admission.\n\nExclusion Criteria:\n\n* High clinical suspicion for Legionella pneumonia\n* Allergy or contraindication to the use of either azithromycin or doxycycline (usual clinical practice)\n* Antibiotics not for CAP\n* Pregnant women (based on clinical assessment as part of standard of care)\n* Severe CAP as defined by the ATS\u002FIDSA criteria\n* Corrected QT prolongation (\\> 440 ms in men and \\> 460 ms in women)\n* Receiving a different antibiotic (e.g quinolones)\n* Admission \\> 24 hours\n* Known to be a prisoner","ALL","18 Years",{"count":122,"type":123},1120,"ESTIMATED","INTERVENTIONAL",[126],"PHASE4","The purpose of this study is to compare effectiveness and safety of Azithromycin versus Doxycycline in adult patients hospitalized with community acquired pneumonia (CAP) treated with Beta-lactams.",[129],"Community-acquired Pneumonia",[27,22,131],"hospitalized","2026-07-01",{"date":134,"type":135},"2026-07-02","ACTUAL",{"date":137,"type":135},"2025-09-15",{"date":139,"type":123},"2031-09-01",{"name":5,"class":6},5]