[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568224":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":38,"locations":48,"responsibleParty":67,"collaborators":26,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":26,"eligibilityCriteria":74,"healthyVolunteers":71,"sex":75,"minAge":76,"maxAge":26,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":90,"overallStatus":51,"whyStopped":26,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Nordsjaellands Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","EXPERIMENTAL","Ultrasound-guided brachial plexus nerve block. A total of 30 ml of lidocaine (10 mg\u002Fml) with adrenaline (5 ug\u002Fml) will be administered in multiple injections.",[13],"Procedure: Ultrasound-guided brachial plexus block",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","ACTIVE_COMPARATOR","Haematoma block with local anaesthetics i.e. lidocaine with adrenaline",[19],"Procedure: Haematoma Block",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Ultrasound-guided brachial plexus block","The block will be performed as either a lateral infraclavicular brachial plexus block or an axillary brachial plexus block",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Haematoma Block","Participants will receive no peripheral nerve block and receive a haematoma block, with or without supplemental sedation and\u002For systemic analgesia for the closed reduction according to local guidelines and clinical practices",[15],[32,36],{"name":33,"affiliation":34,"role":35},"Cecilie D Harwood, MD, PhD-fellow","Copenhagen University Hospital - North Zealand","PRINCIPAL_INVESTIGATOR",{"name":37,"affiliation":34,"role":35},"Anne-Sofie Jellestad, MD, PhD-fellow",[39,44],{"name":33,"role":40,"phone":41,"phoneExt":42,"email":43},"CONTACT","48 29 20 12","+45","cecilie.dupont.harwood.01@regionh.dk",{"name":45,"role":40,"phone":46,"phoneExt":42,"email":47},"Anders K Nørskov, MD, PhD","48 29 74 59","anders.kehlet.noerskov@regionh.dk",[49],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Copenhagen University Hospital - North Zealand Hillerød","RECRUITING","Hillerød","Capital Region","3400","Denmark","DK",{"type":58,"coordinates":59},"Point",[60,61],12.30081,55.92791,{"lat":61,"lon":60},[64],{"name":65,"role":40,"phone":66,"phoneExt":26,"email":47},"Anders Kehlet Nørskov, MD, PhD, Associate Professor","+45 48292510",{"type":68,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100568224","phase-4-brachial-plexus-nerve-block-versus-haematoma-block-for-closed-reduction-of-distal-radius-fracture-in-adults---the-block-trial-a-multicentre-randomised-controlled-trial-100568224",false,"NCT06678438","Brachial Plexus Nerve Block Versus Haematoma Block for Closed Reduction of Distal Radius Fracture in Adults - The BLOCK Trial. A Multicentre Randomised Controlled Trial.","Inclusion Criteria:\n\n* Adults (age ≥ 18 years) with a distal radius fracture in need of closed reduction\n\nExclusion Criteria:\n\n* Patients who would never qualify for surgery according to local guidelines\n* Lack of informed consent\n* No Danish Central Person Register (CPR) number\n* Allergies to the trial medication\n* Distal radius fracture initially deemed to require surgery regardless of the outcome of the closed reduction\n* Open fractures (fracture-related wound requiring sutures)\n* Other fractures on the same extremity ((NOT including distal ulna fracture(s))\n* Bilateral distal radius fractures both requiring closed reduction\n* Concomitant medical or surgical condition taking priority over the closed reduction of the distal radius fracture.","ALL","18 Years",{"count":78,"type":79},1716,"ESTIMATED","INTERVENTIONAL",[82],"PHASE4","The aim of the project is to evaluate the beneficial and harmful effects of an ultrasound-guided brachial plexus nerve block for patients with a distal radius (wrist) fracture in the need of realignment of fractured bone endings without cutting the skin (closed reduction), in comparison to a haematoma block, which is standard care in Denmark.\n\nEvery participant will receive one of the following types of anaesthesia for the realignment of the wrist fracture:\n\n1. A nerve block of the arm (plexus brachialis block)\n2. A haematoma block, which is the current standard anaesthesia in the emergency departments.",[85,86,87,88,89],"Distal Radius Fractures","Fracture Dislocation","Fracture Dislocation of Upper Limb Joint","Colles' Fracture","Closed Reduction of Fracture and Application of Plaster Cast",[91,92,93,94,95,96,97,98,99,100],"Lidocaine","Local anaesthesia","Regional anaesthesia","Peripheral nerve block","Brachial plexus block","Lateral infraclavicular block","Axillary plexus block","Distal radius fracture","Colles' fracture","Wrist fracture","2025-06-12",{"date":103,"type":104},"2025-06-17","ACTUAL",{"date":106,"type":104},"2024-12-10",{"date":108,"type":79},"2027-04",{"name":5,"class":6},1]