[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100502636":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":37,"locations":44,"responsibleParty":61,"collaborators":42,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":42,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":42,"enrollmentInfo":73,"targetDuration":42,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":46,"whyStopped":42,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Loyola University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Interscalene block with the addition of buprenorphine, clonidine, dexamethasone","EXPERIMENTAL","Interscalene brachial plexus blocks (ISB) is performed with a 22g x 50 mm PAJUNK SonoPlexⓇ II Facet S echogenic needle. Once adequate needle visualization is achieved within the correct anatomic position and plane, 30mL of 0.5% bupivacaine with 100 mcg clonidine, 0.3 mg buprenorphine, and 4 mg dexamethasone will be injected.",[13],"Drug: Interscalene block with the addition of buprenorphine, clonidine, dexamethasone",{"label":15,"type":16,"description":17,"interventionNames":18},"Interscalene block with buprenorphine alone","ACTIVE_COMPARATOR","Interscalene brachial plexus blocks (ISB) is performed with a 22g x 50 mm PAJUNK SonoPlexⓇ II Facet S echogenic needle. Once adequate needle visualization is achieved within the correct anatomic position and plane 30mL of 0.5% bupivacaine will be injected.",[19],"Drug: Interscalene block with buprenorphine alone",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Addition of the adjuvant buprenorphine, dexamethasone, and clonidine in the nerve block performed prior to shoulder arthroscopy surgery",[9],[26],"Nerve block with buprenorphine, clonidine, dexamethasone",{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"Addition of the adjuvant buprenorphine alone the in nerve block performed prior to shoulder arthroscopy surgery",[15],[31],"Nerve block with buprenorphine alone",[33],{"name":34,"affiliation":35,"role":36},"Audrice Francois, MD","Loyola University Chicago","PRINCIPAL_INVESTIGATOR",[38],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},"Susan Fargo","CONTACT","708-216-8046",null,"sfargo@luc.edu",[45],{"facility":35,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Maywood","Illinois","60153","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-87.84312,41.8792,{"lat":56,"lon":55},[59,60],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},{"name":34,"role":36,"phone":42,"phoneExt":42,"email":42},{"type":36,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"Audrice Francois, MD, FASA","Professor","100502636","phase-4-buprenorphine-clonidine-and-dexamethasone-on-duration-of-brachial-plexus-blocks-for-upper-extremity-surgery-100502636",false,"NCT05824832","Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery","Effects of a Triple Adjuvant Combination of Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery, a Prospective, Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients ≥ 18 years old\n* Patients undergoing shoulder arthroscopy\n* Patients willing to participate and sign informed consent\n\nExclusion Criteria:\n\n* Severe COPD\u002Fother contraindication to general anesthesia\n* Patient with a weight of less than 60 kg\n* Dementia, not alert or oriented to person, place, or time\n* Chronic pain patient with daily opioid use at home.\n* Patient with allergy to local anesthetics\n* Patient refusal\n* Total shoulder arthroplasty\n* Concomitant pain in different area from operative site.\n* Pregnancy\n* Patient with active infection on the injection sites for the blocks\n* Patients unable or willing to understand or comply with the study protocol","ALL","18 Years",{"count":74,"type":75},120,"ESTIMATED","INTERVENTIONAL",[78],"PHASE4","The goal of this clinical trial is to learn if there is a difference in morphine requirements in patients after upper extremity surgeries including shoulder arthroscopy. The main question it aims to answer is whether there is a difference between Interscalene brachial plexus blocks with the addition of buprenorphine, dexamethasone, and clonidine and the same block without the adjuvant.",[81],"Pain, Postoperative",[83,84,85,86,87,88,89],"buprenorphine","clonidine","dexamethasone","brachial plexus blocks","pain","shoulder","surgery","2025-03-04",{"date":92,"type":93},"2025-03-07","ACTUAL",{"date":95,"type":93},"2023-02-28",{"date":97,"type":75},"2026-06-30",{"name":5,"class":6},1]