[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571444":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":35,"locations":26,"responsibleParty":41,"collaborators":26,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":26,"eligibilityCriteria":50,"healthyVolunteers":47,"sex":51,"minAge":52,"maxAge":26,"enrollmentInfo":53,"targetDuration":26,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":64,"whyStopped":26,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":26},{"fullName":5,"class":6},"Assiut University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"group A","EXPERIMENTAL","Patients will receive 18 ml 0.5% bupivacaine (Sunnypivacaine®) plus 0.5 µg\u002Fkg of dexmedetomidine (Precedex® 100 µg\u002Fml) diluted in 2 ml of normal saline at each side",[13,14],"Drug: bupivacaine 0.5%","Drug: Dexmedetomidine",{"label":16,"type":10,"description":17,"interventionNames":18},"group b","patients will receive 18 ml 0.5% bupivacaine (Sunnypivacaine®) plus 1.5 mL (150 mg) MgSO4 and 0.5 mL normal saline at each side",[13,19],"Drug: MgSO4",[21,27,31],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","bupivacaine 0.5%","patients will receive 18 ml 0.5% bupivacaine (Sunnypivacaine®) using Ultrasound-Guided TAP Block Technique",[9,16],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Dexmedetomidine","patients will receive plus 0.5 µg\u002Fkg of dexmedetomidine (Precedex® 100 µg\u002Fml) diluted in 2 ml of normal saline at each side",[9],{"type":22,"name":32,"description":33,"armGroupLabels":34,"otherNames":26},"MgSO4","patients will receive plus 1.5 mL (150 mg) MgSO4 and 0.5 mL normal saline at each side",[16],[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Abdelrahman Mahfouz Ali, resident doctor","CONTACT","+2 01023864487","AbdElrahman.15235516@med.aun.edu.eg",{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Abdelrahman Mahfouz Ali","resident doctor at Anaesthesia, Intensive Care and Pain Management department Faculty of Medicine, Assiut University","100571444","phase-4-comparative-study-between-the-analgesic-effect-of-dexmedetomidine-and-magnesium-sulfate-as-adjuvant-to-bupivacaine-using-ultrasound-guided-transversus-abdominis-plane-block-in-abdominal-hysterectomy--a-randomized-double-blinded-study-100571444",false,"NCT06720337","Comparative Study Between the Analgesic Effect of Dexmedetomidine and Magnesium Sulfate as Adjuvant to Bupivacaine Using Ultrasound-Guided Transversus Abdominis Plane Block in Abdominal Hysterectomy : A Randomized Double-blinded Study","Inclusion Criteria:\n\n* ASA classification I-ll,\n* Aged \\>18 years,\n* weight 50-85 kg,\n* Patients who will undergo total abdominal hysterectomy\n\nExclusion Criteria:\n\n* • ASA classification I-ll,\n\n  * Aged \\>18 years,\n  * weight 50-85 kg,\n  * Patients who will undergo total abdominal hysterectomy","ALL","18 Years",{"count":54,"type":55},64,"ESTIMATED","INTERVENTIONAL",[58],"PHASE4","Over 80% of patients who undergo surgery suffer from acute postoperative pain, with 75% of them rating the pain severity as moderate, severe, or extreme. Studies have shown that less than 50% of patients who undergo surgery report adequate relief from postoperative pain.\n\nAdditionally, if pain is not promptly managed after surgery, it can hinder a patient's ability to walk, potentially causing adverse effects such as thromboembolism, myocardial ischemia, and arrhythmia.\n\nThe opioid analgesics are most commonly used as parenteral agents to manage post operative pain but the problem of respiratory depression remains to be considered.\n\nThis study is designed to compare the analgesic effect between dexmedetomidine versus magnesium sulfate as adjuvant to bupivacaine using ultrasound guided Transversus Abdominis Plane block in patients undergoing abdominal hysterectomy",[61],"Hysterectomy",[63],"ultrasound-Guided Transversus Abdominis Plane Block","NOT_YET_RECRUITING","2024-12-03",{"date":67,"type":68},"2024-12-06","ACTUAL",{"date":70,"type":55},"2025-01-01",{"date":72,"type":55},"2026-02-01",{"name":5,"class":6}]