[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100484637":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":32,"centralContacts":36,"locations":43,"responsibleParty":72,"collaborators":74,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":79,"sex":85,"minAge":41,"maxAge":41,"enrollmentInfo":86,"targetDuration":41,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":96,"overallStatus":46,"whyStopped":41,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"The University of Texas Health Science Center at San Antonio","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"quetiapine","ACTIVE_COMPARATOR","Elderly patients with dementia-related psychosis will be treated with quetiapine, an atypical antipsychotic indicated for the treeatment of: schizophrenia, bipolar I manic episodes and bipolar depressive episodes.",[13],"Drug: Quetiapine",{"label":15,"type":10,"description":16,"interventionNames":17},"pimavanserin","Elderly patients with dementia-related psychosis will be treated with pimavanserin, an atypical antipsychotic indicated for treatment of hallucinations and delusions associated with Parkinson's disease.",[18],"Drug: Pimavanserin",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Pimavanserin","Dosage choice and further medication management will be at the discretion of the treating clinician, per routine clinical practice.",[15],[26],"Nuplazid",{"type":21,"name":28,"description":23,"armGroupLabels":29,"otherNames":30},"Quetiapine",[9],[31],"Seroquel",[33],{"name":34,"affiliation":5,"role":35},"Sarah Horn, MD","PRINCIPAL_INVESTIGATOR",[37],{"name":38,"role":39,"phone":40,"phoneExt":41,"email":42},"Carolyn Paiz, BS","CONTACT","210-450-8830",null,"paizc@uthscsa.edu",[44,63],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"University Health System","RECRUITING","San Antonio","Texas","78229","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-98.49363,29.42412,{"lat":56,"lon":55},[59,62],{"name":34,"role":39,"phone":60,"phoneExt":41,"email":61},"210-450-0500","horns@uthscsa.edu",{"name":38,"role":39,"phone":40,"phoneExt":41,"email":42},{"facility":64,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":65,"geoPoint":67,"contacts":68},"UT Health Science Center - San Antonio",{"type":53,"coordinates":66},[55,56],{"lat":56,"lon":55},[69,71],{"name":70,"role":39,"phone":40,"phoneExt":41,"email":42},"Carolyn Paiz",{"name":34,"role":35,"phone":41,"phoneExt":41,"email":41},{"type":73,"investigatorFullName":41,"investigatorTitle":41,"investigatorAffiliation":41,"oldNameTitle":41,"oldOrganization":41},"SPONSOR",[75],{"name":76,"class":6},"Alzheimer's Association","100484637","phase-4-comparing-antipsychotic-medications-in-lbd-over-time-100484637",false,"NCT05590637","Comparing Antipsychotic Medications in LBD Over Time","A Pragmatic Randomized Trial Comparing Antipsychotics in Lewy Body Disease","CAMELOT","Inclusion Criteria:\n\n* Patients seen in the neurology clinic at UT Health San Antonio\n* Diagnosed with psychosis due to PD or DLB\n* Requiring initiation of an antipsychotic medication\n* Clinical equipoise between quetiapine and pimavanserin must exist\n* The prescribing provider must be comfortable prescribing and managing both quetiapine and pimavanserin\n\nExclusion Criteria:\n\n* Medical contraindication to either medication\n* Caregiver unavailable to complete NPI-Q\n* Currently taking an antipsychotic medication\n* Prescribing provider unwilling to manage either medication","ALL",{"count":87,"type":88},94,"ESTIMATED","INTERVENTIONAL",[91],"PHASE4","The primary objective of this study is to determine whether treatment with pimavanserin or quetiapine is associated with a greater improvement in psychosis when used in a routine clinical setting to treat hallucinations and\u002For delusions due to Parkinson's disease (PD) or dementia with Lewy bodies (DLB) - collectively referred to as Lewy body disease (LBD).",[94,95],"Parkinson's Disease Psychosis","Dementia With Lewy Bodies",[9,15,97,98,99],"psychosis","hallucinations","delusions","2025-09-08",{"date":102,"type":103},"2025-09-09","ACTUAL",{"date":105,"type":103},"2022-04-22",{"date":107,"type":88},"2027-02",{"name":5,"class":6},2]