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Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)","Inclusion Criteria:\n\n* Age ≥40 years\n* Chronic obstructive pulmonary disease with acute exacerbation, unspecified: ICDJ44\n\nExclusion Criteria:\n\n* All diagnoses that would merit treatment with a specific corticosteroid\n* Pregnant or breastfeeding women\n* Active tuberculosis or invasive fungal infection","ALL","40 Years",{"count":189,"type":190},2000,"ESTIMATED","INTERVENTIONAL",[193],"PHASE4","The goal of this cluster randomized controlled trial is to determine the optimal treatment for Acute Exacerbation of Chronic Obstructive Pulmonary Disease. The study compares the effects and side effects of hydrocortisone and prednisolone in patients above 40 years old diagnosed with chronic obstructive pulmonary disease with acute exacerbation. The main question is whether there is a difference in readmission for COPD excerbation or all cause mortality within thirty days.\n\nParticipants will randomized to receive treatment with either hydrocortisone or prednisolone.",[196],"Chronic Obstructive Pulmonary Disease (COPD)","2026-03-16",{"date":199,"type":200},"2026-03-18","ACTUAL",{"date":202,"type":200},"2026-03-10",{"date":204,"type":190},"2030-11-01",{"name":5,"class":6},14]