[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560685":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":53,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":25,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":74,"overallStatus":79,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Hitit University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"\"Sennoside A+B Group\" for bowel preparation.","ACTIVE_COMPARATOR","This study will compare two bowel preparation methods in patients undergoing colonoscopy:\n\nSennoside A+B Group\n\nIntervention: Patients will take Sennoside A+B, a stimulant laxative derived from the senna plant.\n\nPurpose: To cleanse the colon by increasing bowel movements and reducing water absorption.",[13],"Drug: Sennosid A+B",{"label":15,"type":10,"description":16,"interventionNames":17},"\"PM\u002FCa Group\" for bowel preparation.","PM\u002FCa Group (Sodium Picosulfate\u002FMagnesium Oxide\u002FCitric Acid)\n\nIntervention: Patients will take a combination of sodium picosulfate (a stimulant laxative) and magnesium oxide\u002Fcitric acid (osmotic agents).\n\nPurpose: To promote bowel movements by stimulating the bowel and drawing water into the colon.",[18],"Drug: Sodium Picosulfate\u002FMagnesium Oxide\u002FCitric Acid",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Sennosid A+B","Bowel Preparation",[9],null,{"type":21,"name":27,"description":23,"armGroupLabels":28,"otherNames":25},"Sodium Picosulfate\u002FMagnesium Oxide\u002FCitric Acid",[15],[30],{"name":31,"affiliation":5,"role":32},"İbrahim Durak","STUDY_CHAIR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","+903642193000","durak.ibrahim@gmail.com",{"name":31,"role":35,"phone":36,"phoneExt":25,"email":25},[40],{"facility":41,"status":25,"city":42,"state":25,"zip":43,"country":44,"countryCode":25,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Hitit University Erol Olcok Training and Research Hospital","Çorum","19030","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],34.95333,40.54889,{"lat":49,"lon":48},[52],{"name":31,"role":35,"phone":25,"phoneExt":25,"email":25},{"type":54,"investigatorFullName":31,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Medical Doctor","100560685","phase-4-comparing-sennosid-ab-and-sodium-picosulfatemagnesium-oxidecitric-acid-for-bowel-preparation-100560685",false,"NCT06580366","Comparing Sennosid A+B and Sodium Picosulfate\u002FMagnesium Oxide\u002FCitric Acid for Bowel Preparation","Sennosid A+B Versus Sodium Picosulfate\u002FMagnesium Oxide\u002FCitric Acid for Bowel Preparation; A Prospective Randomized Observer-Blinded Study","Inclusion Criteria:\n\n* Adults aged 18-80 years scheduled for elective outpatient colonoscopy.\n* Ability to provide informed consent.\n\nExclusion Criteria:\n\n* History of intra-abdominal surgery.\n* Chronic kidney failure.\n* Congestive heart failure.\n* Chronic liver failure.\n* Inflammatory bowel disease.\n* Electrolyte imbalance.\n* Hospitalized patients.\n* Patients unable to use the bowel preparation treatment\n* Known allergy or hypersensitivity to Sennoside A+B or PM\u002FCa components\n* Known gastrointestinal motility disorders.","ALL","18 Years","80 Years",{"count":67,"type":68},600,"ESTIMATED","INTERVENTIONAL",[71],"PHASE4","Colonoscopy Preparation: Comparing Sennoside A+B and PM\u002FCa\n\nColonoscopy is a test used to examine the inside of the bowel. Proper bowel preparation is crucial because it helps doctors get a clear view during the procedure.\n\nWhat is Sennoside A+B? Sennoside A+B is a type of laxative made from the senna plant. It works by stimulating the bowel to move and reducing the absorption of water, making it easier to pass stools. Research has shown that high doses of sennoside A+B can be effective for bowel preparation.\n\nSennoside A+B vs. PEG:\n\nSome studies have found that sennoside A+B is more effective than PEG, another laxative, but can cause more abdominal pain. Other studies have found no significant difference in effectiveness between the two.\n\nWhat is Picosulfate\u002FMagnesium Oxide\u002FCitric Acid (PM\u002FCa)? PM\u002FCa is a combination of sodium picosulfate, magnesium oxide, and citric acid. Sodium picosulfate stimulates bowel movements, while magnesium oxide and citric acid help increase water in the bowel, making it easier to pass stools.\n\nPM\u002FCa vs. PEG:\n\nResearch has shown that PM\u002FCa is as effective as PEG for bowel preparation. Patients using PM\u002FCa generally tolerate the preparation process better than those using PEG.\n\nConclusion:\n\nWhile PEG is the preferred option according to guidelines, its high cost can make it less accessible in some places. In this study, we aim to compare the effectiveness and patient tolerance of Sennoside A+B and PM\u002FCa since no direct comparison between these two preparations has been made before.",[23],[75,76,77,78],"Bowel preparation","Colonoscopy","sennosid A+B","Sodium Picosulfate","NOT_YET_RECRUITING","2024-08-28",{"date":82,"type":83},"2024-08-30","ACTUAL",{"date":85,"type":68},"2024-08-22",{"date":87,"type":68},"2025-03-22",{"name":5,"class":6},1]