[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633138":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":25,"responsibleParty":44,"collaborators":25,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":25,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":25,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":68,"whyStopped":25,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":25},{"fullName":5,"class":6},"Hayatabad Medical Complex","OTHER_GOV",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"ethyl ascorbic acid Group","ACTIVE_COMPARATOR","The participants in this arm will receive only topical ethyl ascorbic acid",[13,14],"Drug: Ethyl ascorbic acid topical application","Drug: Tranxemic acid topical application",{"label":16,"type":10,"description":17,"interventionNames":18},"Topical tranexamic acid group","Participants in this group will receive only topical tranexamic acid",[13,14],[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Ethyl ascorbic acid topical application","The participants in this arm of study will only receive topical ethyl ascorbic acid once daily at night for 12 weeks",[16,9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Tranxemic acid topical application","The participants in this arm will receive only topical tranexamic acid once daily for 12 weeks",[16,9],[31],{"name":32,"affiliation":5,"role":33},"aneeqa khan","STUDY_CHAIR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Aneeqa Aneeqa Khan, Mbbs","CONTACT","+923409259017","aneeqakhan1419@gmail.com",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Ayesha Ayesha Naeem, Mbbs","03459133233","Ayeshasaddozai976@gmail.com",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Naheed asghar","Associate professor Dermatology unit HMC","100633138","phase-4-comparison-between-efficacy-of-topical-tranexamic-acid-vs-topical-ethyl-ascorbic-acid-in-treatment-of-melasma-100633138",false,"NCT07522788","Comparison Between Efficacy of Topical Tranexamic Acid Vs Topical Ethyl Ascorbic Acid In Treatment Of Melasma","Inclusion Criteria:\n\n* Adults age 18 to 50 years Clinically diagnosed Melasma Irrespective of gender and ethnicity\n\nExclusion Criteria:\n\n* pregnant and lactating women Patients with a history of skin allergies to study medications Use of systemic steroides or anti coagulants within the last month Patients on other melasma treatments for atleast 4 weeks prior",true,"ALL","18 Years","50 Years",{"count":59,"type":60},128,"ESTIMATED","INTERVENTIONAL",[63],"PHASE4","This study is to compare the efficacy of topical tranexamic acid vs topical ethyl ascorbic acid in the treatment of melasma",[66],"Melasma",[66],"NOT_YET_RECRUITING","2026-04-04",{"date":71,"type":72},"2026-04-13","ACTUAL",{"date":74,"type":60},"2026-06-01",{"date":76,"type":60},"2026-11-30",{"name":5,"class":6}]