[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638845":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":59,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":25,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":86,"whyStopped":25,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"PAEC General Hospital, Islamabad","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"0.5% hyperbaric bupivacaine group","ACTIVE_COMPARATOR","Patients will receive spinal anesthesia with 0.5% hyperbaric bupivacainefor cystoscopic procedures.hemodynamic parameters will be monitored and compared with other group.",[13],"Drug: 0.5% Hyperbaric Bupivicaine",{"label":15,"type":10,"description":16,"interventionNames":17},"0.75% hyperbaric bupivacaine group","Patients will receive spinal anesthesia with 0.75% hyperbaric bupivacaine for cystoscopic procedures.hemodynamic stability and related outcomes will be assesed and compared with 0.5% group.",[18],"Drug: 0.75% hyperbaric bupivacaine",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","0.5% Hyperbaric Bupivicaine","0.5% hyperbaric bupivacaine will be administered intrathecally for spinal anesthesia in patients undergoing cystoscopic procedures.hemodynamic parameters,systolic blood pressure and heart rate will be monitored, and its effects on hemodynamic stability will be assesed and compared with other intervention.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"0.75% hyperbaric bupivacaine","0.75% hyperbaric bupivacaine will be administered intrathecally duringspinal anesthesia in patients undergoing cystoscopic procedures.hemodynamic parameters will be monitored ,and its effects on hemodynamic stability will be assesed and compared with 0.5% bupivacaine.",[15],[31],{"name":32,"affiliation":5,"role":33},"Dr Salbia Bibi, FCPS","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","+923330335004","dr.salbia@yahoo.com",[40],{"facility":41,"status":25,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"PAEC General Hospital Islamabad","Islamabad","Punjab Province","44000","Pakistan","PK",{"type":48,"coordinates":49},"Point",[50,51],74.4039,31.6047,{"lat":51,"lon":50},[54,58],{"name":55,"role":36,"phone":56,"phoneExt":25,"email":57},"Dr Asghar Khan Niazi, FCPS","+923325061749","asghar852@yahoo.com",{"name":32,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":33,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Salbia Bibi","Postgraduate Trainee","100638845","phase-4-comparison-of-hemodynamic-stability-with-075percent-and-05percent-hyperbaric-bupivacaine-during-spinal-anesthesia-in-cystoscopic-procedures-100638845",false,"NCT07590544","Comparison of Hemodynamic Stability With 0.75percent and 0.5percent Hyperbaric Bupivacaine During Spinal Anesthesia in Cystoscopic Procedures","Comparison of Hemodynamic Stability With 0.75 vs 0.5percent Hyperbaric Bupivacaine During Spinal Anesthesia in Cystoscopic Procedures:A Randomized Control Trial","Inclusion Criteria:\n\n* Patients aged 18-80 years. American society of Anesthesiologist(ASA) physical status I-II. Sceduled for elective cystoscopic procedures under spinal anesthesia.\n\nExclusion Criteria:\n\n* Patient refusal. Contraindication to spinal anesthesia(e.g coagulopathy ,infection at injection site).\n\nKnown hypersensitivity to bupivacaine. Significant cardiovascular,hepatic or renal disease.","ALL","18 Years","80 Years",{"count":73,"type":74},60,"ESTIMATED","INTERVENTIONAL",[77],"PHASE4","Purpose:The aim of this study is to determine the intrathecal Bupivacaine concentration(0.5% vs 0.75%) with better anesthesia and little hemodynamic disturbance during cystoscopic procedures.In comparing these bupivacaine concentrations ,the result would be expected to enhance safer spinal anesthesia practices ,minimizing the use of vasopressors in urological surgeries.OBJECTIVE:To compare and analyze the frequency and average chages of post spinal hemodynamic instability in terms of hypotension and bradycardia with 0.75% hyperbaric bupivacaine and 0.55 hyperbaric bupivacaine in patients presenting for cystoscopic procedures.",[80],"Cystoscopy",[82,83,84,85],"spinal anesthesia","hyperbaric bupivacaine","cystoscopy","hemodynamic stability","NOT_YET_RECRUITING","2026-05-10",{"date":89,"type":90},"2026-05-15","ACTUAL",{"date":92,"type":74},"2026-07",{"date":94,"type":74},"2026-12",{"name":5,"class":6},1]