[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600231":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":37,"centralContacts":37,"locations":37,"responsibleParty":38,"collaborators":37,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":37,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":49,"minAge":50,"maxAge":37,"enrollmentInfo":51,"targetDuration":37,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":37,"overallStatus":62,"whyStopped":37,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":37},{"fullName":5,"class":6},"Tribhuvan University Teaching Hospital, Institute Of Medicine.","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Morphine Group","ACTIVE_COMPARATOR","This group will receive 2.2 ml of 0.5% hyperbaric bupivacaine + 100 mcg (0.1 ml of 1 mg\u002Fml) Morphine intrathecally during spinal anesthesia",[13],"Drug: Intrathecal morphine with bupivacaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Bupivacaine Group","PLACEBO_COMPARATOR","This group will receive 2.2 ml of 0.5% hyperbaric bupivacaine during spinal anesthesia",[19],"Drug: Hyperbaric Bupivicaine",[21,30],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Intrathecal morphine with bupivacaine","Participants will receive 100 mcg intrathecal morphine along with 2.2ml of 0.5% hyperbaric bupivacaine",[9],[27,28,29],"morphine","opioids","intrathecal morphine",{"type":22,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Hyperbaric Bupivicaine","0.5% hyperbaric Bupivacaine 2.2 ml",[15],[35,36],"Bupivacaine","hyperbaric bupivacaine",null,{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":37,"oldOrganization":37},"PRINCIPAL_INVESTIGATOR","Megha Patrabansha","Dr., Resident","100600231","phase-4-comparison-of-intrathecal-bupivacaine-with-and-without-morphine-for-post-operative-analgesia-in-parturients-undergoing-elective-cesarean-section-a-randomized-controlled-trial-100600231",false,"NCT07094802","Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Parturients undergoing elective caesarean section under Spinal anesthesia\n* ASA PS II, III\n* \\> 18 years\n\nExclusion Criteria:\n\n* Refusal to Participate\n* Contraindications to spinal anaesthesia and adjuvants INR ≥ 1.5 Plateletes \\\u003C 1,00,000\u002Fcumm Severe aortic stenosis, and\u002For severe mitral stenosis Infection at lumbar puncture site Known allergy to local anesthetics and opioids\n* Communication barrier\n* Height \\\u003C150 cm",true,"FEMALE","18 Years",{"count":52,"type":53},92,"ESTIMATED","INTERVENTIONAL",[56],"PHASE4","The goal of this clinical trial is to compare intrathecal bupivacaine with or without morphine for postoperative analgesia in patients undergoing elective cesarean section. The main questions it aims to answer are:\n\nIs intrathecal bupivacaine with morphine superior to intrathecal bupivacaine alone for postoperative analgesia for parturients undergoing cesarean section? What is the duration of analgesia in the two groups? Researchers will compare drug intrathecal bupivacaine with morphine to a iintrathecal bupivacaine alone to see if intrathecal morphine has benefits for psotoperative analgesia .\n\nParticipants will:\n\nGet intrathecal bupivacaine with Morphine or intrathecal bupivacaine alone during spinal anesthesia for cesarean section.\n\nThey will be followed up for NRS pain scores and side effects for 24 hours. Time to need of first rescue analgesic will be noted",[59,60,61],"Postoperative Pain","Cesarean Delivery","Analgesia, Obstetrical","NOT_YET_RECRUITING","2025-07-23",{"date":65,"type":66},"2025-07-30","ACTUAL",{"date":68,"type":53},"2025-10-15",{"date":70,"type":53},"2026-08-15",{"name":5,"class":6}]