[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555062":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":38,"locations":44,"responsibleParty":62,"collaborators":42,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":42,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":42,"enrollmentInfo":74,"targetDuration":42,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":86,"overallStatus":47,"whyStopped":42,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Chung-Ang University Gwangmyeong Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Remimazolam group","EXPERIMENTAL","General anesthesia is induced by continuously injecting remimazolam (6 mg\u002Fkg\u002Fh) and remifentanil (2-6 ng\u002Fml, target concentration controlled infusion) through an infusion pump. Afterwards, when the patient loses consciousness, rocuronium 0.6 mg\u002Fkg is injected for endotracheal intubation, and anesthesia is maintained with remimazolam (1-2 mg\u002Fkg\u002Fhr) and remifentanil after endotracheal intubation. When the surgery is completed, all anesthetic drugs being administered are stopped, and general anesthesia is terminated with flumazenil and sugammadex.",[13],"Drug: Remimazolam",{"label":15,"type":16,"description":17,"interventionNames":18},"Propofol group","ACTIVE_COMPARATOR","General anesthesia is induced by continuously injecting propofol (2-6 mg\u002Fml, target concentration controlled injection) and remifentanil (2-6 ng\u002Fml, target concentration controlled injection) using a TCI infusion pump. Afterwards, when the patient loses consciousness, rocuronium 0.6mg\u002Fkg is injected for endotracheal intubation, and anesthesia is maintained with propofol and remifentanil after endotracheal intubation. When the surgery is completed, all anesthetic drugs being administered are stopped, and general anesthesia is terminated through sugammadex.",[19],"Drug: Propofol",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Remimazolam","General anesthesia is induced and maintained by continuous infusion of remimazolam and remifentanil, and recovered with flumazenil.",[9],[27],"Byfavo",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Propofol","General anesthesia is induced and maintained by continuous infusion of propofol and remifentanil.",[15],[33],"Fresofol",[35],{"name":36,"affiliation":5,"role":37},"Se-Hee Min","STUDY_CHAIR",[39],{"name":36,"role":40,"phone":41,"phoneExt":42,"email":43},"CONTACT","+820222221534",null,"seiheemin@gmail.com",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":42,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"ChungAng University Gwangmyeong Hospital","RECRUITING","Gyeonggi-do","Gwangmyeon-si","14353","South Korea",{"type":53,"coordinates":54},"Point",[55,56],126.76917,37.58944,{"lat":56,"lon":55},[59],{"name":60,"role":40,"phone":61,"phoneExt":42,"email":43},"Seihee Min","821054004892",{"type":63,"investigatorFullName":36,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"PRINCIPAL_INVESTIGATOR","Assistant professor","100555062","phase-4-comparison-of-remimazolam-and-propofol-for-recovery-of-ambulatory-upper-airway-surgery-100555062",false,"NCT06507202","Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery","Comparison of Remimazolam Versus Propofol-based General Anesthesia on Postoperative Quality of Recovery in Patients Undergoing Ambulatory Upper Airway Surgery: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult patients (age 19 or older) undergoing ambulatory upper respiratory tract (nasal cavity, oral cavity, pharynx, larynx) surgery under general anesthesia\n* American Society of Anesthesiologists physical class classification I, II, and III\n\nExclusion Criteria:\n\n* Patients who refused to participate in the study\n* Pregnant patients\n* Patients with a history of hypersensitivity to drugs or additives used during surgery\n* Patients with acute narrow-angle glaucoma\n* Alcohol or drug dependent patients\n* Patients with Child-Pugh class C liver dysfunction","ALL","19 Years",{"count":75,"type":76},116,"ESTIMATED","INTERVENTIONAL",[79],"PHASE4","The purpose of this study is to compare the effects of remimazolam and propofol on postoperative recovery time, complications, and safety in patients undergoing ambulatory upper airway surgery under general anesthesia.",[82,83,84,85],"Laryngeal Disease","Pharyngeal Diseases","Oral Cavity Disease","Nasal Disease",[87,88,89],"remimazolam","upper airway surgery","ambulatory surgery","2024-07-11",{"date":92,"type":93},"2024-07-18","ACTUAL",{"date":95,"type":93},"2024-01-22",{"date":97,"type":76},"2025-03-22",{"name":5,"class":6},1]