[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575859":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":32,"centralContacts":39,"locations":49,"responsibleParty":68,"collaborators":28,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":15,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":28,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":94,"overallStatus":52,"whyStopped":28,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Kaohsiung Veterans General Hospital.","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Propofol","ACTIVE_COMPARATOR","The patient underwent a routine upper gastrointestinal endoscopy.",[13],"Drug: Propofol",{"label":15,"type":16,"description":17,"interventionNames":18},"Remimazolam","EXPERIMENTAL","The patient underwent routine upper gastrointestinal endoscopy and Remimazolam was substituted for Propofol.",[19],"Drug: Remimazolam",{"label":21,"type":16,"description":22,"interventionNames":23},"Propofol + Remimazolam","The patient underwent routine upper gastrointestinal endoscopy, and the anesthetic drug used was Propofol combined with Remimazolam.",[19,13],[25,29],{"type":26,"name":15,"description":15,"armGroupLabels":27,"otherNames":28},"DRUG",[21,15],null,{"type":26,"name":9,"description":30,"armGroupLabels":31,"otherNames":28},"Propofol dose reduction ratio",[9,21],[33,37],{"name":34,"affiliation":35,"role":36},"CHIA-HAO YANG, M.D","employe","PRINCIPAL_INVESTIGATOR",{"name":38,"affiliation":35,"role":36},"Tzung-Jim Tsai, M.D",[40,46],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},"Yuan-Yi Chia, M.D","CONTACT","886-7-342-2121","74105","yychia@vghks.gov.tw",{"name":47,"role":42,"phone":43,"phoneExt":44,"email":48},"Chen-Hsiu Chen, Ph.D","chschen@vghks.gov.tw",[50],{"facility":51,"status":52,"city":53,"state":28,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Kaohsiung Veterans General Hospital","RECRUITING","Kaohsiung City","81362","Taiwan","TW",{"type":58,"coordinates":59},"Point",[60,61],120.31333,22.61626,{"lat":61,"lon":60},[64,67],{"name":65,"role":42,"phone":43,"phoneExt":44,"email":66},"Yuan-Yi Chia, Bachelor","yychia@isca.vghks.gov.tw",{"name":47,"role":42,"phone":43,"phoneExt":44,"email":48},{"type":36,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"Yuan-Yi Chia","Department Director","100575859","phase-4-comparison-of-remimazolam-and-propofol-in-endoscopic-examinations-and-treatments-100575859",false,"NCT06777758","Comparison of Remimazolam and Propofol in Endoscopic Examinations and Treatments","The Comparison of Remimazolam or Propofol Used Alone Versus in Combination for Moderate Sedation During Endoscopic Examination and Treatment.","Inclusion Criteria:\n\n* Subjects are between 20-80 years old.\n* Anesthesiologists rated ASA as between I and III.\n* Patients undergoing upper gastrointestinal endoscopic examination or therapy.\n\nExclusion Criteria:\n\n* Allergy to Propofol, Remimazolam, or opioid medications.\n* Emergency surgery.\n* Pregnancy.\n* History of malignant hyperthermia.\n* Impaired liver or kidney function.\n* Airway difficulties due to pharyngeal tumors.\n* Refusal to participate.","ALL","20 Years","80 Years",{"count":82,"type":83},90,"ESTIMATED","INTERVENTIONAL",[86],"PHASE4","This study aims to evaluate the efficacy and safety of Remimazolam, either used alone or in combination with Propofol, for moderate sedation anesthesia during endoscopic therapies or examinations. Additionally, it seeks to explore whether their combination can further enhance the quality of patient anesthesia and recovery outcomes.",[89,90,91,92,93],"Postoperative Complications","Respiratory Depression","Postoperative Nausea","Vomiting","Constipation",[95,96,97,98,99],"endoscope","Respiratory depression","Remimazolam、","Sedation","BYFAVO","2025-05-06",{"date":102,"type":103},"2025-05-08","ACTUAL",{"date":105,"type":103},"2025-02-12",{"date":107,"type":83},"2026-12-31",{"name":5,"class":6},1]