[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614608":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":24,"responsibleParty":34,"collaborators":24,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":42,"acronym":24,"eligibilityCriteria":43,"healthyVolunteers":44,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":24,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":24,"overallStatus":58,"whyStopped":24,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":24},{"fullName":5,"class":6},"Shaheed Zulfiqar Ali Bhutto Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A: piroxicam","EXPERIMENTAL","Group A: patients will be given piroxicam 20mg as premedication",[13],"Drug: piroxicam 20mg",{"label":15,"type":16,"description":17,"interventionNames":18},"Group B: prednisolone","ACTIVE_COMPARATOR","Group B: patients will be given prednisolone 20mg as premedication",[19],"Drug: Group B: patients will be given prednisolone 20mg as premedication",[21,25],{"type":22,"name":17,"description":17,"armGroupLabels":23,"otherNames":24},"DRUG",[15],null,{"type":22,"name":26,"description":11,"armGroupLabels":27,"otherNames":24},"piroxicam 20mg",[9],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"rana ahmad, B.D.S., F.C.P.S.","CONTACT","+923335990799","ranam_ahmad@hotmail.com",{"type":35,"investigatorFullName":36,"investigatorTitle":37,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","RANA AHMAD","Dr","100614608","phase-4-comparison-of-the-pain-levels-of-single-dose-premedication-with-piroxicam-and-prednisolone-on-post-endodontic-pain-in-single-visit-root-canal-treatment-of-premolars-100614608",false,"NCT07281807","Comparison of the Pain Levels of Single-Dose Premedication With Piroxicam and Prednisolone on Post-Endodontic Pain in Single-Visit Root Canal Treatment of Premolars","Inclusion Criteria:\n\n* Healthy patient ranging between 18-40 years\n* Having at least one premolar with diagnosis of symptomatic irreversible pulpitis according to history, examination and radiographs.\n* Teeth having mature apex confirmed by periapical radiographs.\n\nExclusion Criteria:\n\n* History of systemic disorders including HIV, Hepatitis\n\n  * Pregnancy (As per Medical record\u002F Verbally)\n  * Patient using medication such as analgesics or anti-inflammatory drugs\n  * Patient allergic to lignocaine, piroxicam and prednisolone\n  * Tooth not suitable for restoration\n  * Periodontal probing depth ≥ 4mm\n  * Retreatment cases\n  * Patients having calcified canals assessed by radiographic findings",true,"ALL","18 Years","40 Years",{"count":49,"type":50},60,"ESTIMATED","INTERVENTIONAL",[53],"PHASE4","To compare the post operative mean pain scores by administering single-dose preoperative piroxicam and prednisolone in patients of irreversible pulpitis with symptomatic apical periodontitis.",[56,57],"Irreversible Pulpitis With Apical Periodontitis","Symptomatic Apical Periodontitis","NOT_YET_RECRUITING","2025-12-02",{"date":61,"type":62},"2025-12-15","ACTUAL",{"date":64,"type":50},"2026-01-01",{"date":66,"type":50},"2027-01-31",{"name":36,"class":6}]