[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553786":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":33,"centralContacts":38,"locations":43,"responsibleParty":48,"collaborators":43,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":43,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":43,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":43,"overallStatus":71,"whyStopped":43,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":43},{"fullName":5,"class":6},"Kasr El Aini Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dexmedetomidine group","EXPERIMENTAL","Patients will be subjected to SCPB consisting of bupivacaine 0.25%, dexmedetomidine 1 μg\u002Fkg (precedex 100mcg\u002Fml), and adrenaline 1:200,000 in a total volume of 10ml normal saline.",[13],"Drug: Dexmedetomidine in superficial cervical plexus block",{"label":15,"type":10,"description":16,"interventionNames":17},"Nalbuphine group","Patients will be subjected to SCPB consisting of bupivacaine 0.25% and 10 mg of Nalbuphine (nalufin 20mg\u002Fml) and adrenaline 1:200,000 in a total volume of 10ml normal saline.",[18],"Drug: Nalbuphine in superficial cervical plexus block",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Dexmedetomidine in superficial cervical plexus block","While the patient is in the supine position, the head will be turned to the opposite side of the surgical incision, and a line extending from the mastoid process to the clavicular head of the sternomastoid muscle will be marked. Aseptic preparation of this area will be done, and then the block needle will be inserted at the midpoint of this line with injection of bupivacaine 0.25%, dexmedetomidine 1 μg\u002Fkg (precedex 100mcg\u002Fml), and adrenaline 1:200,000 in a total volume of 10ml normal saline in the above, below, and middle directions subcutaneously, creating a sausage-shaped swelling. The sensory block will be assessed with ice chips in the dermatome corresponding to the block, which included the skin of the neck, upper chest, shoulder, and ear, until the completion of the sensory blockade.",[9],[26],"Percedex",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Nalbuphine in superficial cervical plexus block","While the patient is in the supine position, the head will be turned to the opposite side of the surgical incision, and a line extending from the mastoid process to the clavicular head of the sternomastoid muscle will be marked. Aseptic preparation of this area will be done, and then the block needle will be inserted at the midpoint of this line with injection of bupivacaine 0.25%, 10 mg of Nalbuphine (nalufin 20mg\u002Fml), and adrenaline 1:200,000 in a total volume of 10ml normal saline in the above, below, and middle directions subcutaneously, creating a sausage-shaped swelling. The sensory block will be assessed with ice chips in the dermatome corresponding to the block, which included the skin of the neck, upper chest, shoulder, and ear, until the completion of the sensory blockade.",[15],[32],"Nalufin",[34],{"name":35,"affiliation":36,"role":37},"Doaa F El Hamalawy, Lecturer","Kasr Al-Aini hospital-Faculty of Medicine- Cairo University","STUDY_DIRECTOR",[39,45],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Amira M Mohamed, Resident","CONTACT","+20 1285223474",null,"amiraa485.m@gmail.com",{"name":35,"role":41,"phone":46,"phoneExt":43,"email":47},"+20 1151518514","Fz.doaa@hotmail.com",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":43,"oldOrganization":43},"PRINCIPAL_INVESTIGATOR","Doaa Fawzy Abd El Fattah Hassan","Lecturer of anesthesia,surgical ICU and pain management","100553786","phase-4-dexmedetomidine-and-nalbuphine-as-analgesic-adjuvants-to-bupivacaine-in-superficial-cervical-block-100553786",false,"NCT06490614","Dexmedetomidine and Nalbuphine as Analgesic Adjuvants to Bupivacaine in Superficial Cervical Block.","Comparative Study Between Dexmedetomidine and Nalbuphine as Analgesic Adjuvants to Bupivacaine in Superficial Cervical Block for Patients Undergoing Anterior Cervical Discectomy and Fusion (ACDF) Surgery A Double Blinded Randomized Trial","Inclusion Criteria:\n\n* Physical status ASA I and ASA ll.\n* Both males and females\n* Age 21- 60 years.\n* Patients undergoing elective anterior cervical discectomy and fusion for 1 or 2 levels.\n\nExclusion Criteria:\n\n* Patient refusal.\n* Patients undergoing anterior cervical vertebrectomy and reconstruction.\n* Patients with a history of allergy to local anesthetics or any used drugs in study.\n* Infection at the site of the block.\n* Patients with multiple cervical spine traumas.\n* Patients having surgery for malignant tumors.\n* Pre-existing peripheral neuropathies.\n* Pregnant female.\n* Patients with uncontrolled hypertension or cardiac problems as (heart block, sick sinus syndrome and ischemic heart disease).\n* Patients with coagulopathy (INR\\>1.5).\n* Patients with failed block.","ALL","21 Years","60 Years",{"count":63,"type":64},30,"ESTIMATED","INTERVENTIONAL",[67],"PHASE4","Anterior cervical discectomy and fusion (ACDF) nowadays is considered a common procedure.postoperative pain can hinder recovery and prolong hospital stay. The superficial cervical plexus block (SCPB) is a safe and simple technique that had been found to allow good pain relief in neck surgeries. The main drawback of SCPB was short duration, so adjuvants as dexmedetomidine and opioids has been used to increase analgesic duration and decrease the use of opioids.\n\nThe current study will compare the efficacy of dexmedetomidine and nalbuphine as adjuvants to bupivacaine in SCPB in anterior cervical fusion surgeries.",[70],"Anterior Cervical Discectomy and Fusion (ACDF)","NOT_YET_RECRUITING","2024-07-05",{"date":74,"type":75},"2024-07-08","ACTUAL",{"date":77,"type":64},"2024-07",{"date":79,"type":64},"2024-11",{"name":5,"class":6}]