[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613765":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":40,"centralContacts":45,"locations":55,"responsibleParty":315,"collaborators":49,"id":319,"slug":320,"hasResults":321,"nctId":322,"briefTitle":323,"officialTitle":324,"acronym":325,"eligibilityCriteria":326,"healthyVolunteers":321,"sex":327,"minAge":328,"maxAge":49,"enrollmentInfo":329,"targetDuration":49,"studyType":332,"phases":333,"briefSummary":335,"conditions":336,"keywords":338,"overallStatus":344,"whyStopped":49,"lastUpdateSubmitDate":345,"lastUpdatePostDateStruct":346,"startDateStruct":349,"completionDateStruct":351,"leadSponsor":353,"locationsCount":354},{"fullName":5,"class":6},"Inha University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dronedarone","EXPERIMENTAL","Participants assigned to this arm will receive dronedarone 400 mg twice daily.",[13],"Drug: Dronedarone",{"label":15,"type":16,"description":17,"interventionNames":18},"Class Ic Antiarrhythmic Drugs","ACTIVE_COMPARATOR","Participants assigned to this arm will receive a Class Ic antiarrhythmic drug (investigator's choice of flecainide or propafenone) according to standard clinical practice.",[19,20],"Drug: flecainide","Drug: propafenone",[22,29,35],{"type":23,"name":9,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Dronedarone 400 mg administered orally twice daily.",[9],[27,28],"Multaq","Drone Tab.",{"type":23,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"flecainide","Administered orally according to standard clinical practice.",[15],[34],"Tambocor",{"type":23,"name":36,"description":31,"armGroupLabels":37,"otherNames":38},"propafenone",[15],[39],"Rytmonorm",[41],{"name":42,"affiliation":43,"role":44},"Yong-Soo Baek, M.D., Ph.D.","Division of Cardiology, Department of Internal Medicine, Inha University College of Medicine and Inha University Hospital, Incheon, Republic of Korea.","STUDY_CHAIR",[46,51],{"name":42,"role":47,"phone":48,"phoneExt":49,"email":50},"CONTACT","+82-32-890-2200",null,"existsoo@inha.ac.kr",{"name":52,"role":47,"phone":53,"phoneExt":49,"email":54},"Hyoung Seok Lee, M.D.","+82-32-890-3575","hyoungseok_lee@inha.ac.kr",[56,72,89,107,125,143,160,178,192,201,218,236,254,268,282,297],{"facility":5,"status":49,"city":57,"state":57,"zip":58,"country":59,"countryCode":49,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"Incheon","22332","South Korea",{"type":61,"coordinates":62},"Point",[63,64],126.70515,37.45646,{"lat":64,"lon":63},[67,71],{"name":68,"role":47,"phone":69,"phoneExt":49,"email":70},"Hyerim Park","+82-32-890-2114","rimvely1126@naver.com",{"name":42,"role":47,"phone":48,"phoneExt":49,"email":50},{"facility":73,"status":49,"city":74,"state":49,"zip":75,"country":59,"countryCode":49,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Korea University Ansan Hospital","Ansan","15355",{"type":61,"coordinates":77},[78,79],126.52613,35.46836,{"lat":79,"lon":78},[82,86],{"name":83,"role":47,"phone":84,"phoneExt":49,"email":85},"Sangmi Oh","+82-31-412-5114","osm221001@gmail.com",{"name":87,"role":47,"phone":84,"phoneExt":49,"email":88},"Seung-yong Shin, M.D., Ph.D.","theshin04@naver.com",{"facility":90,"status":49,"city":91,"state":49,"zip":92,"country":59,"countryCode":49,"cosmosGeoPoint":93,"geoPoint":97,"contacts":98},"Soonchunhyang University Bucheon Hospital","Bucheon-si","14584",{"type":61,"coordinates":94},[95,96],126.78306,37.49889,{"lat":96,"lon":95},[99,103],{"name":100,"role":47,"phone":101,"phoneExt":49,"email":102},"Sunyoung Yoo","032-621-6825","smurfet1298@naver.com",{"name":104,"role":47,"phone":105,"phoneExt":49,"email":106},"Hyung-oh Choi, M.D., Ph.D.","+82-32-621-5114","mrgud@hanmail.net",{"facility":108,"status":49,"city":109,"state":49,"zip":110,"country":59,"countryCode":49,"cosmosGeoPoint":111,"geoPoint":115,"contacts":116},"Kosin University Gospel Hospital","Busan","49267",{"type":61,"coordinates":112},[113,114],129.03004,35.10168,{"lat":114,"lon":113},[117,121],{"name":118,"role":47,"phone":119,"phoneExt":49,"email":120},"Eun-ah Park","+82-51-990-6114","euna0725@naver.com",{"name":122,"role":47,"phone":123,"phoneExt":49,"email":124},"Sungil Lim, M.D., Ph.D.","051-990-6705","sungils8932@kosin.ac.kr",{"facility":126,"status":49,"city":127,"state":49,"zip":128,"country":59,"countryCode":49,"cosmosGeoPoint":129,"geoPoint":133,"contacts":134},"Soonchunhyang University Cheonan Hospital","Cheonan","31151",{"type":61,"coordinates":130},[131,132],127.1522,36.8065,{"lat":132,"lon":131},[135,139],{"name":136,"role":47,"phone":137,"phoneExt":49,"email":138},"Jiwon Jeon","041-570-2384","Mail_z1@schmc.ac.kr",{"name":140,"role":47,"phone":141,"phoneExt":49,"email":142},"Hayoung Choi, M.D., Ph.D.","+82-41-570-2114","inter0019@naver.com",{"facility":144,"status":49,"city":145,"state":49,"zip":146,"country":59,"countryCode":49,"cosmosGeoPoint":147,"geoPoint":151,"contacts":152},"Inje University Ilsan Paik Hospital","Goyang","10380",{"type":61,"coordinates":148},[149,150],127.19731,36.21689,{"lat":150,"lon":149},[153,157],{"name":154,"role":47,"phone":155,"phoneExt":49,"email":156},"Hye-young Kye","+82-31-910-7114","honey2720@naver.com",{"name":158,"role":47,"phone":155,"phoneExt":49,"email":159},"June Namgung, M.D., Ph.D.","jnamgung@paik.ac.kr",{"facility":161,"status":49,"city":162,"state":49,"zip":163,"country":59,"countryCode":49,"cosmosGeoPoint":164,"geoPoint":168,"contacts":169},"NHIS Ilsan Hospital","Goyang-si","10444",{"type":61,"coordinates":165},[166,167],126.835,37.65639,{"lat":167,"lon":166},[170,174],{"name":171,"role":47,"phone":172,"phoneExt":49,"email":173},"Saerom Kim","+82-31-900-3931","crcsrk8610@nhimc.or.kr",{"name":175,"role":47,"phone":176,"phoneExt":49,"email":177},"Hancheol Lee, M.D., Ph.D.","031-900-0977","cardiocharles@nhimc.or.kr",{"facility":179,"status":49,"city":162,"state":49,"zip":180,"country":59,"countryCode":49,"cosmosGeoPoint":181,"geoPoint":183,"contacts":184},"Myongji Hospital","10475",{"type":61,"coordinates":182},[166,167],{"lat":167,"lon":166},[185,189],{"name":186,"role":47,"phone":187,"phoneExt":49,"email":188},"Jieun Park","+82-31-810-5114","04145019@hanmail.net",{"name":190,"role":47,"phone":187,"phoneExt":49,"email":191},"Eui-seok Hwang, M.D., Ph.D.","cvmdhes@gmail.com",{"facility":193,"status":49,"city":194,"state":49,"zip":195,"country":59,"countryCode":49,"cosmosGeoPoint":196,"geoPoint":200,"contacts":49},"Hanyang University Guri Hospital","Guri-si","11923",{"type":61,"coordinates":197},[198,199],127.1394,37.5986,{"lat":199,"lon":198},{"facility":202,"status":49,"city":203,"state":49,"zip":204,"country":59,"countryCode":49,"cosmosGeoPoint":205,"geoPoint":209,"contacts":210},"Jeju National University Hospital","Jeju City","63241",{"type":61,"coordinates":206},[207,208],126.52194,33.50972,{"lat":208,"lon":207},[211,215],{"name":212,"role":47,"phone":213,"phoneExt":49,"email":214},"Jin-hee Kim","+82-64-717-6000","wpwndurh77@naver.com",{"name":216,"role":47,"phone":213,"phoneExt":49,"email":217},"Ki Yung Boo, M.D., Ph.D.","pidori@hanmail.net",{"facility":219,"status":49,"city":220,"state":49,"zip":221,"country":59,"countryCode":49,"cosmosGeoPoint":222,"geoPoint":226,"contacts":227},"Sejong Chungnam National University Hospital","Sejong","30099",{"type":61,"coordinates":223},[224,225],127.29223,36.59245,{"lat":225,"lon":224},[228,232],{"name":229,"role":47,"phone":230,"phoneExt":49,"email":231},"Heejin 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Song","+82-1599-1004","cardiocrc66@yuhs.ac",{"name":266,"role":47,"phone":263,"phoneExt":49,"email":267},"Hee Tae Yu, M.D., Ph.D.","HEETYU@yuhs.ac",{"facility":269,"status":49,"city":238,"state":49,"zip":270,"country":59,"countryCode":49,"cosmosGeoPoint":271,"geoPoint":273,"contacts":274},"Ewha Womans University Seoul Hospital","07804",{"type":61,"coordinates":272},[242,243],{"lat":243,"lon":242},[275,279],{"name":276,"role":47,"phone":277,"phoneExt":49,"email":278},"Soohee Kwon","+82-1666-5000","suhe_e@hanmail.net",{"name":280,"role":47,"phone":277,"phoneExt":49,"email":281},"Yeji Kim, M.D., Ph.D.","lexie6169@gmail.com",{"facility":283,"status":49,"city":238,"state":49,"zip":284,"country":59,"countryCode":49,"cosmosGeoPoint":285,"geoPoint":287,"contacts":288},"Korea University Guro Hospital","08308",{"type":61,"coordinates":286},[242,243],{"lat":243,"lon":242},[289,293],{"name":290,"role":47,"phone":291,"phoneExt":49,"email":292},"Yoonhee Choi","+82-2--2626-2336","grkmcgrca009@kumc.or.kr",{"name":294,"role":47,"phone":295,"phoneExt":49,"email":296},"Dae-in Lee, M.D., Ph.D.","+82-2-2626-1114","acttopia@gmail.com",{"facility":298,"status":49,"city":299,"state":49,"zip":300,"country":59,"countryCode":49,"cosmosGeoPoint":301,"geoPoint":305,"contacts":306},"Wonju Severance Christian Hospital","Wŏnju","26426",{"type":61,"coordinates":302},[303,304],127.94528,37.35139,{"lat":304,"lon":303},[307,311],{"name":308,"role":47,"phone":309,"phoneExt":49,"email":310},"Goeun Seol","033-741-0910","forheart99@gmail.com",{"name":312,"role":47,"phone":313,"phoneExt":49,"email":314},"Youngjoon Park, M.D., Ph.D.","+82-33-741-0114","pyj@yonsei.ac.kr",{"type":316,"investigatorFullName":317,"investigatorTitle":318,"investigatorAffiliation":5,"oldNameTitle":49,"oldOrganization":49},"PRINCIPAL_INVESTIGATOR","Yong-Soo Baek","Associate Professor","100613765","phase-4-dronedarone-rhythm-intervention-for-early-atrial-fibrillation-100613765",false,"NCT07270848","Dronedarone Rhythm Intervention for Early Atrial Fibrillation","A Multicenter Prospective Study on the Efficacy, Safety, and Quality of Life Improvements of Dronedarone for Early Rhythm Control in Atrial Fibrillation","DRIVE-AF","Inclusion Criteria:\n\n* Participants who have voluntarily provided written informed consent to participate.\n* Adults aged 19 years or older.\n* Life expectancy of at least 1 year.\n* Diagnosis of atrial fibrillation within the past 1 year.\n* Participants with an indication for antiarrhythmic drug therapy (Dronedarone or Class Ic agents).\n\nExclusion Criteria:\n\n* History of failure with prior antiarrhythmic drug therapy.\n* Confirmed severe structural heart disease (e.g., heart failure with reduced ejection fraction \\[LVEF \\\u003C= 40%\\], moderate or severe mitral stenosis, mechanical heart valve replacement, or dilated cardiomyopathy).\n* Diagnosis of permanent atrial fibrillation.\n* Severe renal impairment (eGFR \\\u003C 30 mL\u002Fmin\u002F1.73m\\^2 or on dialysis) or severe hepatic impairment (Child-Pugh class B or higher) that restricts the use of antiarrhythmic drugs.\n* Known contraindications to dronedarone or Class Ic antiarrhythmic drugs.\n* Participation in another clinical trial within 3 months prior to randomization.\n* Participants who do not agree to refrain from participating in another clinical trial within 14 days after their participation in this study ends.\n* Pregnant or breastfeeding women, or women of childbearing potential who do not agree to use effective contraception during the study.\n* Any other condition that, in the opinion of the investigator, makes the participant unsuitable for study participation.","ALL","19 Years",{"count":330,"type":331},1898,"ESTIMATED","INTERVENTIONAL",[334],"PHASE4","The purpose of this study is to compare two commonly used types of medicine for treating atrial fibrillation (also called AF), a condition that causes an irregular heart rhythm. This study is for adults who have been diagnosed with AF within the past year.\n\nResearchers want to find out which medicine is more effective, safer, and provides a better quality of life for patients needing to control their heart rhythm.\n\nParticipants who agree to join the study will be randomly assigned (like flipping a coin) to one of two groups:\n\nGroup 1: Will receive the medicine Dronedarone.\n\nGroup 2: Will receive a standard medicine from the 'Class Ic' group (such as flecainide or propafenone).\n\nThe study will follow participants for at least 12 months. Researchers will compare how well each medicine works to prevent AF from coming back. They will also carefully track any side effects and changes in participants' quality of life during the study.",[337],"Atrial Fibrillation (AF)",[339,9,340,341,342,343],"Atrial Fibrillation","Flecainide","Propafenone","Antiarrhythmic Drugs","Rhythm Control","NOT_YET_RECRUITING","2025-12-15",{"date":347,"type":348},"2025-12-22","ACTUAL",{"date":350,"type":331},"2026-01-01",{"date":352,"type":331},"2028-12",{"name":5,"class":6},16]