[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582198":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":32,"centralContacts":33,"locations":32,"responsibleParty":39,"collaborators":32,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":32,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":32,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":68,"whyStopped":32,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":32},{"fullName":5,"class":6},"TC Erciyes University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Ah plus+MDA","EXPERIMENTAL","Ah plus will be used as the root canal sealer and manual dynamic activation will be used for irrigation agitation.",[13],"Drug: Root Canal Sealants",{"label":15,"type":10,"description":16,"interventionNames":17},"Ah plus+PUA","Ah plus will be used as the root canal sealer and pasive ultrasonic agitation will be used for irrigation agitation.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Neosealer Flo+MDA","Neosealer Flo will be used as the root canal sealer and manual dynamic activation will be used for irrigation agitation.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Neosealer Flo+PUA","Neosealer Flo will be used as the root canal sealer and pasive ultrasonic agitation will be used for irrigation agitation.",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DRUG","Root Canal Sealants","In this study, different irrigation agitation methods and different root canal sealers will be compared.",[9,15,19,23],null,[34],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"İpek A ERASLAN AKYÜZ","CONTACT","+9 5385591409","ipekemamak@hotmail.com",{"type":40,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"PRINCIPAL_INVESTIGATOR","Ipek Eraslan Akyuz","Research assistant","100582198","phase-4-effect-of-different-sealers-and-activation-methods-on-pain-100582198",false,"NCT06860191","Effect of Different Sealers and Activation Methods on Pain","Evaluation of the Effects of Different Root Canal Sealer and Irrigation Agitation Methods on Postoperative Pain in the Treatment of Teeth with Chronic Apical Periodontitis - Prospective Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients aged 18-60 years who are classified as medically healthy (ASA I or II),\n* Teeth that do not need periodontal and prosthetic treatment, with a periapical index score between 2 and 4,\n* Teeth with single root and canal diagnosed with asymptomatic apical periodontitis,\n* Teeth that respond negatively to electric pulp test (Parkell) or cold test (Endo Ice; Coltene, Altstätten, İsviçre), without pain during percussion and palpation.\n\nExclusion Criteria:\n\n* Teeth with PAI scores lower than 2\n* Patients who had taken analgesics or anti-inflammatory drugs in the last 4 hours\n* Diabetic, immunocompromised, pregnant or history of antibiotic use in the last month or patients receiving antibiotic prophylaxis\n* Teeth with root resorption, immature, severe crown damage, calcified canals, and previous root canal fillings",true,"ALL","18 Years","60 Years",{"count":55,"type":56},80,"ESTIMATED","INTERVENTIONAL",[59],"PHASE4","In this study, the effects of different irrigation agitation methods and different root canal filling sealers on postoperative pain after root canal treatment will be evaluated.",[62],"Chronic Apical Periodontitis",[64,65,66,67],"Caries","apical periodontitis","irrigation agitation","root canal sealer","NOT_YET_RECRUITING","2025-02-28",{"date":71,"type":72},"2025-03-05","ACTUAL",{"date":74,"type":56},"2025-03-01",{"date":76,"type":56},"2025-05-01",{"name":5,"class":6}]