[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100484866":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":26,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":26,"eligibilityCriteria":63,"healthyVolunteers":60,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":26,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"China Medical University, China","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"lithium carbonate","EXPERIMENTAL","Patients undergoing heart valve surgery with cardiopulmonary bypass will take 250mg lithium carbonate .",[13],"Drug: Lithium Carbonate 250 MG Oral Tablet",{"label":15,"type":16,"description":17,"interventionNames":18},"calcium carbonate","PLACEBO_COMPARATOR","Patients undergoing heart valve surgery with cardiopulmonary bypass will take 500mg calcium carbonate.",[19],"Drug: Calcium Carbonate 500 MG Oral Tablet",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Lithium Carbonate 250 MG Oral Tablet","Patients undergoing heart valve surgery withcardiopulmonary bypass will take 250mg lithium carbonate",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Calcium Carbonate 500 MG Oral Tablet","Patients undergoing heart valve surgery withcardiopulmonary bypass will take 500mg calcium carbonate",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Wenfei Tan","CONTACT","024-83283100","winfieldtan@hotmail.com",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"the First Hospital of China Medical University","RECRUITING","Shenyang","Liaoning","110001","China","CN",{"type":47,"coordinates":48},"Point",[49,50],123.43278,41.79222,{"lat":50,"lon":49},[53],{"name":54,"role":34,"phone":35,"phoneExt":26,"email":36},"Wenfei Tan, M.D.,Ph.D",{"type":56,"investigatorFullName":33,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Professor","100484866","phase-4-effect-of-lithium-carbonate-on-postoperative-sleep-and-cognitive-function-in-patients-undergoing-heart-valve-surgery-with-cardiopulmonary-bypass-100484866",false,"NCT05593627","Effect of Lithium Carbonate on Postoperative Sleep and Cognitive Function in Patients Undergoing Heart Valve Surgery With Cardiopulmonary Bypass","Inclusion Criteria:\n\n* Ethnic Chinese;\n* Age, 18 to 65 years old;\n* Patients undergoing heart valve surgery with cardiopulmonary bypass\n\nExclusion Criteria:\n\n* Preoperative Pittsburgh Sleep Quality Index global scores higher than 6\n* Cognitive difficulties\n* Partial or complete gastrectomy\n* Previous esophageal surgery\n* Previous treated by radiotherapy or surgery\n* Inability to conform to the study's requirements\n* Body mass index exceeding 30 kg\u002Fm2\n* Deprivation of a right to decide by an administrative or juridical entity\n* Ongoing participation or participation in another study \\\u003C1 month ago\n* Recent (\\\u003C 3 months prior) use of antibiotics, probiotics, prebiotics, symbiotics, hormonal medication, laxatives, proton pump inhibitors, insulin sensitizers or traditional Chinese medicine","ALL","18 Years","65 Years",{"count":68,"type":69},62,"ESTIMATED","INTERVENTIONAL",[72],"PHASE4","It has been proved that lithium carbonate can prolong slow wave sleep with few or no side-effects. The aim of the present study is to evaluate postoperative sleep quality of patients undergoing heart valve surgery with cardiopulmonary bypass taken 250mg lithium carbonate after surgery.",[75],"Heart Valve Surgery",[9,77],"polysomnography","2023-07-14",{"date":80,"type":81},"2023-07-18","ACTUAL",{"date":83,"type":81},"2023-07-01",{"date":85,"type":69},"2026-07-30",{"name":5,"class":6},1]