[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548755":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":37,"locations":46,"responsibleParty":82,"collaborators":29,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":29,"eligibilityCriteria":91,"healthyVolunteers":87,"sex":92,"minAge":93,"maxAge":29,"enrollmentInfo":94,"targetDuration":29,"studyType":97,"phases":98,"briefSummary":100,"conditions":101,"keywords":29,"overallStatus":49,"whyStopped":29,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"China National Center for Cardiovascular Diseases","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Xuesaitong Soft Capsule","EXPERIMENTAL","Each participant in the Xuesaitong Soft Capsule treatment group will take a daily dose of 1.32g.",[13],"Drug: Xuesaitong Soft Capsule",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Each participant in the placebo group will take matching placebo.",[19],"Drug: Placebo",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Each participant in the xuesaitong soft capsule treatment group will take a daily dose of 1.32g.",[9],[26],"LixuwangⓇ",{"type":22,"name":15,"description":17,"armGroupLabels":28,"otherNames":29},[15],null,[31,35],{"name":32,"affiliation":33,"role":34},"Jing Li, MD, PhD","National Center for Cardiovascular Diseases","PRINCIPAL_INVESTIGATOR",{"name":36,"affiliation":33,"role":34},"Jiamin Liu, MD",[38,42],{"name":32,"role":39,"phone":40,"phoneExt":29,"email":41},"CONTACT","+86 (010) 6086 6077","jing.li@fwoxford.org",{"name":43,"role":39,"phone":44,"phoneExt":29,"email":45},"Yan Li, MD","+86 (010) 6086 6795","liyan@fuwai.com",[47,66],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Fuwai Hospital, Chinese Academy of Medical Sciences","RECRUITING","Beijing","Beijing Municipality","100087","China","CN",{"type":56,"coordinates":57},"Point",[58,59],116.39723,39.9075,{"lat":59,"lon":58},[62],{"name":63,"role":39,"phone":64,"phoneExt":29,"email":65},"Ying Sun, BA","18310888612","ying.sun@fwoxford.org",{"facility":67,"status":68,"city":69,"state":70,"zip":29,"country":53,"countryCode":54,"cosmosGeoPoint":71,"geoPoint":75,"contacts":76},"Affiliated Hospital of Nantong University","NOT_YET_RECRUITING","Nantong","Jiangsu",{"type":56,"coordinates":72},[73,74],120.87472,32.03028,{"lat":74,"lon":73},[77,81],{"name":78,"role":39,"phone":79,"phoneExt":29,"email":80},"Linsheng Shi, MD, PhD","+86 13813719088","shlsh@139.com",{"name":78,"role":34,"phone":29,"phoneExt":29,"email":29},{"type":34,"investigatorFullName":83,"investigatorTitle":84,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"Jing Li","JingLi, MD, PhD, professor","100548755","phase-4-effect-of-xuesaitong-soft-capsules-on-major-risk-factors-in-patients-with-coronary-heart-disease-100548755",false,"NCT06425120","Effect of Xuesaitong Soft Capsules on Major Risk Factors in Patients With Coronary Heart Disease","Effect of Xuesaitong Soft Capsules on Major Risk Factors in Patients With Coronary Heart Disease: a Multicenter, Randomized, Double-blind, Placebo-controlled Trial","Inclusion Criteria:\n\n1. Age ≥18 years old\n2. Chronic coronary artery disease: meet any of the following conditions, and the condition is stable for at least 3 months:\n\n   1. History of myocardial infarction\n   2. Have received coronary interventional therapy\n   3. There are symptoms of myocardial ischemia (such as chest pain) and objective evidence (stress electrocardiogram or stress myocardial perfusion imaging indicated myocardial ischemia or coronary artery stenosis ≥50% )\n3. High-sensitivity C-reactive protein ≥2mg\u002FL\n4. Currently taking moderate or above intensity statins lipid-lowering drugs\n5. Currently taking antiplatelet drugs\n6. Sign informed consent\n\nExclusion Criteria:\n\n* Patients fulfilling any of the following criteria are not eligible for inclusion in this trial:\n\n  1. Acute coronary syndrome occurred or received percutaneous coronary intervention therapy within the past 3 months\n  2. Previously received coronary artery bypass grafting\n  3. Stroke occurred within the previous 3 months\n  4. Symptomatic heart failure (HF) in the past, or documented left ventricular ejection fraction \\\u003C 35%\n  5. Revascularization or surgical procedures are planned within the next 3 months\n  6. Progressive neuromuscular disease, or creatine kinase (CK) levels \\> 3 times the normal upper limit (ULN)\n  7. Lupus, inflammatory bowel disease, severe arthritis and other inflammatory diseases\n  8. Immunosuppressants such as cyclosporine, tacrolimus, azathioprine, or systemic steroids are currently being taken or planned during the study\n  9. History of hereditary dyslipidemia such as familial hypercholesterolemia\n  10. There has been a change in lipid regulation treatment within the past 1 month, or there is a current adjustment plan\n  11. History of symptomatic non-traumatic cerebral hemorrhage at any time in the past\n  12. History of gastrointestinal bleeding or major surgery within the past 6 months\n  13. Use of Xuesaitong soft capsules or preparations containing the main ingredients of Xuesaitong in the past 1 month\n  14. There were clear adverse reactions to the main components of Xuesaitong in the past\n  15. Active liver disease, or alanine aminotransferase (ALT) levels \\> 3 times the upper limit of normal (ULN)\n  16. Chronic kidney disease, or estimated glomerular filtration rate (eGFR) \\\u003C60ml\u002F (min×1.73m2)\n  17. Pregnancy or planned pregnancy, or breastfeeding\n  18. Malignant tumors, or other serious diseases with an estimated survival of less than 1 year\n  19. Mental disorders or communication disorders, cognitive impairment, or other serious medical conditions that may affect study participation\n  20. Have participated in or are participating in other clinical trials within the last 1 month\n  21. Poor adherence to follow-up or medication is known","ALL","18 Years",{"count":95,"type":96},240,"ESTIMATED","INTERVENTIONAL",[99],"PHASE4","This trials aims to assess, in 240 eligible patients with coronary heart disease, the effects on level of high-sensitivity C-reactive protein (hsCRP) changes from baseline to 12 weeks of Xuesaitong Soft Capsules.",[102],"Coronary Heart Disease","2025-08-30",{"date":105,"type":106},"2025-09-08","ACTUAL",{"date":108,"type":106},"2024-06-01",{"date":110,"type":96},"2026-12-31",{"name":5,"class":6},2]