[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588486":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":29,"centralContacts":30,"locations":36,"responsibleParty":47,"collaborators":29,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":29,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":29,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":74,"whyStopped":29,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Aydin Adnan Menderes University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental 1","EXPERIMENTAL","Ozonated water",[13],"Drug: Control 1",{"label":15,"type":10,"description":16,"interventionNames":17},"Experimental 2","hypochlorous acid",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"Control 1","ACTIVE_COMPARATOR","%0.12 chlorhexidine gluconate",[13],[24],{"type":25,"name":19,"description":26,"armGroupLabels":27,"otherNames":28},"DRUG","Researchers will perform oral care with ozonated water and hypochlorous acid solution to restore oral mucous membrane integrity.",[19,9,15],[21],null,[31],{"name":32,"role":33,"phone":34,"phoneExt":29,"email":35},"Sercan Özdemir","CONTACT","+90 256 220 29 00","sercanoz15@hotmail.com",[37],{"facility":38,"status":29,"city":39,"state":29,"zip":29,"country":40,"countryCode":29,"cosmosGeoPoint":41,"geoPoint":46,"contacts":29},"Aydın Adnan Menderes Univercity","Aydin","Turkey (Türkiye)",{"type":42,"coordinates":43},"Point",[44,45],27.83963,37.84501,{"lat":45,"lon":44},{"type":48,"investigatorFullName":32,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100588486","phase-4-effects-of-chlorhexidine-gluconate-ozonated-water-and-hypochlorous-acid-solutions-used-in-the-oral-care-of-patients-supported-by-mechanical-ventilation-on-the-integrity-of-the-oral-mucosa-100588486",false,"NCT06942026","Effects of Chlorhexidine Gluconate, Ozonated Water and Hypochlorous Acid Solutions Used in the Oral Care of Patients Supported by Mechanical Ventilation on the Integrity of the Oral Mucosa","Inclusion Criteria:\n\n* Be between the ages of 18-65,\n* Have been on mechanical ventilation for at least 24 hours,\n* Have no intolerance or allergy to the solutions,\n* Agree to participate in the study\n\nExclusion Criteria:\n\n* Having a contraindication for oral care\n* Not agreeing to participate in the study",true,"ALL","18 Years","65 Years",{"count":61,"type":62},63,"ESTIMATED","INTERVENTIONAL",[65],"PHASE4","The purpose of this clinical trial is to learn whether ozonated water and hypochlorous acid solution can restore the integrity of the oral mucosa. In addition, the investigators will learn about the safety of ozonated water and hypochlorous acid solution. The main questions that participants need to answer are:\n\nWhat medical conditions do participants have while taking ozonated water and hypochlorous acid solution?\n\nInvestigators will compare ozonated water and hypochlorous acid solution with 0.12% chlorhexidine gluconate solution to see if it helps to restore the integrity of the oral mucosa.\n\nParticipants:\n\nParticipants will be asked to agree to receive oral care 4 times a day, every day for 1 week.",[68],"Oral Mucosal Disorder",[70,71,72,73],"oral care","Intensive care unit","ozonated water","Oral Mucous Membrane","NOT_YET_RECRUITING","2025-04-16",{"date":77,"type":78},"2025-04-24","ACTUAL",{"date":80,"type":62},"2025-04-27",{"date":82,"type":62},"2025-09-30",{"name":5,"class":6},1]