[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100593417":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":41,"centralContacts":46,"locations":53,"responsibleParty":67,"collaborators":22,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":22,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":22,"enrollmentInfo":79,"targetDuration":22,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":56,"whyStopped":22,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",[8,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Intra-Articular Cocktail Injection","EXPERIMENTAL","After fixation, an intra-articular cocktail injection is injected into the surgical site. The intra-articular cocktail regime: Ketoralac 15mg, Ropivacaine 1% 15ml, 0.9% Normal Saline 35ml, Adrenaline 1:1000 0.5ml, Stacort-A Triamcinolone Acetonide 40mg. The total cocktail volume is approximately 50ml.",[13,14,15,16,17],"Drug: Ketorolac 15mg","Drug: Triamcinolone Acetonide 40mg","Drug: Ropivacaine HCL 1% 15ml","Drug: 0.9 % Normal Saline 35ml","Drug: Adrenaline 1:1000 0.5ml",{"label":19,"type":20,"description":21,"interventionNames":22},"No Injection","NO_INTERVENTION","No injection will be given to the patient.",null,[24,29,32,35,38],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":22},"DRUG","Ketorolac 15mg","An intra-articular cocktail injection ( Ketoralac 15mg, Ropivacaine 1% 15ml, 0.9% Normal Saline 35ml, Adrenaline 1:1000 0.5ml, Stacort-A Triamcinolone Acetonide 40mg) will be injected into the surgical site after fracture fixation surgery.",[9],{"type":25,"name":30,"description":27,"armGroupLabels":31,"otherNames":22},"Triamcinolone Acetonide 40mg",[9],{"type":25,"name":33,"description":27,"armGroupLabels":34,"otherNames":22},"Ropivacaine HCL 1% 15ml",[9],{"type":25,"name":36,"description":27,"armGroupLabels":37,"otherNames":22},"0.9 % Normal Saline 35ml",[9],{"type":25,"name":39,"description":27,"armGroupLabels":40,"otherNames":22},"Adrenaline 1:1000 0.5ml",[9],[42],{"name":43,"affiliation":44,"role":45},"Christian Fang","Dept of Orthopaedics and Traumatology, Queen Mary Hospital","PRINCIPAL_INVESTIGATOR",[47,52],{"name":48,"role":49,"phone":50,"phoneExt":22,"email":51},"Christian FANG","CONTACT","+852 22554581","cfang@hku.hk",{"name":43,"role":49,"phone":22,"phoneExt":50,"email":51},[54],{"facility":55,"status":56,"city":57,"state":57,"zip":22,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Queen Mary Hospital, The University of Hong Kong","RECRUITING","Hong Kong","HK",{"type":60,"coordinates":61},"Point",[62,63],114.17469,22.27832,{"lat":63,"lon":62},[66],{"name":48,"role":49,"phone":50,"phoneExt":22,"email":51},{"type":45,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"Prof. Christian Xinshuo Fang","Clinical Assistant Professor","100593417","phase-4-effects-of-intra-operative-intra-articular-cocktail-injection-in-patella-open-reduction-and-internal-fixation-100593417",false,"NCT07006168","Effects Of Intra-Operative Intra-Articular Cocktail Injection In Patella Open Reduction And Internal Fixation","Effects Of Intra-Operative Intra-Articular Cocktail Injection In Patella Open Reduction And Internal Fixation (ORIF): A Single Centre, Double Blinded, Randomised Control Trial","Inclusion Criteria:\n\n* acute patella fracture requiring open reduction and internal fixation;\n* able to consent to surgery;\n* pre-morbid able to ambulate\n\nExclusion Criteria:\n\n* open fracture;\n* polytrauma;\n* previous knee arthroplasty;\n* history of chronic pain,\n* insulin-dependent diabetes mellitus, or peptic ulcer disease;\n* chronic users of glucocorticoids, immunosuppressants, or immune-modulating agents, or of strong opioids (e.g.: morphine, fentanyl, hydromorphone, methadone, oxycodone, or meperidine);\n* hepatitis B or C carrier;\n* renal impairment (creatinine \\[Cr\\], \\>200 mmol\u002FL)","ALL","18 Years",{"count":80,"type":81},56,"ESTIMATED","INTERVENTIONAL",[84],"PHASE4","The objective of this study is to demonstrate the safety and efficacy of an intra-articular analgesics cocktail injection for post-operative patella fracture fixation patients, by comparing post-operative pain relief and functional recovery among study subjects who received the injection and those who did not receive the injection. Secondary objective is to demonstrate the health economic effects of intra-articular analgesics cocktail injection by reducing length of hospital stay and reducing bed-stay related complications.",[87],"Patella Fracture",[89,90,91,92,93,94,95],"Intra-Articular analgesic injection","Pain relief","Open Reduction and Internal Fixation","Functional Recovery","Rehabilitation","Range of motion","Post-operative recovery","2025-05-27",{"date":98,"type":99},"2025-06-05","ACTUAL",{"date":101,"type":99},"2024-11-01",{"date":103,"type":81},"2027-07-31",{"name":5,"class":6},1]