[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100054105":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":20,"responsibleParty":32,"collaborators":20,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":38,"acronym":20,"eligibilityCriteria":39,"healthyVolunteers":36,"sex":40,"minAge":41,"maxAge":20,"enrollmentInfo":42,"targetDuration":20,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":20,"overallStatus":54,"whyStopped":20,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":20},{"fullName":5,"class":6},"Rutgers, The State University of New Jersey","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Melatonin arm","EXPERIMENTAL","3mg Melatonin will be administered orally to all subjects.",[13],"Drug: Melatonin",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Melatonin","patients in this arm will recieve melatonin",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Jag Sunderram","Rutgers Robert Wood Johnson Medical School","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":20,"email":31},"Jag Sunderram, MD","CONTACT","732-235-7038","sunderja@rwjms.rutgers.edu",{"type":25,"investigatorFullName":28,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Professor of Medicine","100054105","phase-4-effects-of-melatonin-on-sleep-architecture-of-critically-ill-patients-in-the-icu-100054105",false,"NCT07691996","Effects of Melatonin on Sleep Architecture of Critically Ill Patients in the ICU","Inclusion Criteria:\n\n* 18 years or older, admitted to the ICU\n* Expected length of stay of at least 48 hours\n* Not mechanically ventilated\n* Able to take oral medications.\n* Hemodynamically stable as determined by the treating ICU physician\n* Able to provide informed consent or have consent provided by a legally -authorized representative.\n\nExclusion Criteria:\n\n* Mechanically ventilated\n* Currently using melatonin prior to ICU admission,\n* Have neurological conditions that may significantly alter sleep architecture, such as traumatic brain injury, stroke, or severe dementia.\n* Pregnant or lactating individuals\n* Those individuals with a comfort measures-only status","ALL","18 Years",{"count":43,"type":44},30,"ESTIMATED","INTERVENTIONAL",[47],"PHASE4","This is a pilot study to examine the effects of melatonin on the sleep patterns of critically ill patients. Patients will have their sleep patterns measured with a device attached to their head with a headband then be given a dose of melatonin. Their participation in the study will last two days.",[50,51,52,17,53],"Critical Illness","ICU","ICU Hospitalization","Sleep","NOT_YET_RECRUITING","2026-07-09",{"date":57,"type":58},"2026-07-13","ACTUAL",{"date":60,"type":44},"2026-09-01",{"date":62,"type":44},"2028-01",{"name":5,"class":6}]