[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579033":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":61,"collaborators":11,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":11,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":11,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":45,"whyStopped":11,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"The University of Texas Health Science Center, Houston","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"PBM Therapy","EXPERIMENTAL",null,[13,14],"Device: PBM Therapy","Drug: Maalox plus Benadryl",{"label":16,"type":17,"description":11,"interventionNames":18},"Standard of care","ACTIVE_COMPARATOR",[14],[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"DEVICE","patients will receive PBM therapy using the Biolase Epic pro laser. An average power of 0.6w (peak power = 80w, rep. rate= 20Hz). Each aphthous ulcer will be irradiated one time for a total of 30 seconds via continuous wave.",[9],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"DRUG","Maalox plus Benadryl","1:1 mixture of Maalox and Benadryl will be applied to the ulcer as needed for pain. Applications typically will be applied before eating to form a dissolvable oral band-aid that lasts for up to 30 minutes. 10 milliliters of 1:1 Maalox: Benadryl solution will be provided to the family. During the presenting appointment, the patient\u002Ffamily will be shown how to use the 1:1 Maalox: Benadryl solution. It will be applied topically with no rinsing needed.",[9,16],[30],{"name":31,"affiliation":5,"role":32},"Brett Chiquet, DDS, PhD","PRINCIPAL_INVESTIGATOR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":11,"email":37},"CONTACT","(713) 500-8220","Brett.T.Chiquet@uth.tmc.edu",{"name":39,"role":35,"phone":40,"phoneExt":11,"email":41},"Jessica Hochschuler","(713) 486-4141","Jessica.L.Hochschuler@uth.tmc.edu",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"The University of Texas Health Science Center at Houston","RECRUITING","Houston","Texas","77030","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-95.36327,29.76328,{"lat":55,"lon":54},[58,60],{"name":31,"role":35,"phone":59,"phoneExt":11,"email":37},"713-500-8220",{"name":39,"role":35,"phone":40,"phoneExt":11,"email":41},{"type":32,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Brett Thomas Chiquet","Associate Professor","100579033","phase-4-effects-of-photobiomodulation-pbm-on-pain-after-presentation-of-aphthous-ulcers-in-pediatric-dental-patients-100579033",false,"NCT06819033","Effects of Photobiomodulation (PBM) on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients","Effects of Photobiomodulation on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients","Inclusion Criteria:\n\n* Patient\u002Fguardian speaks either English or Spanish\n* Patient presenting with one or more aphthous ulcers in their mouth, identified during a scheduled dental appointment\n* No previous PBM treatment to the presenting aphthous ulcer(s)\n* Guardian able to partake in a follow-up phone call in either the English or Spanish language\n\nExclusion Criteria:\n\n* Patient presents with aphthous ulcers recently treated with PBM\n* Patient presents with herpes labialis (cold sores)\n* Patients presents with systemic disease that affects soft tissue\u002Fmucous healing","ALL","5 Years","17 Years",{"count":75,"type":76},30,"ESTIMATED","INTERVENTIONAL",[79],"PHASE4","The purpose of this study is to compare the efficacy of laser photobiomodulation and \"Magic Mouthwash\" for treatment of pain in pediatric patients with aphthous ulcers , to assess how photobiomodulation influences the rate of healing of aphthous ulcers in pediatric patients and to measure changes in pain levels reported by pediatric patients undergoing photobiomodulation treatment for aphthous ulcers.",[82],"Aphthous Ulcer",[84,85],"magic mouthwash","laser treatment","2025-03-20",{"date":88,"type":89},"2025-03-25","ACTUAL",{"date":91,"type":89},"2025-03-10",{"date":93,"type":76},"2026-02-28",{"name":5,"class":6},1]