[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605127":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":45,"centralContacts":49,"locations":59,"responsibleParty":74,"collaborators":28,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":28,"eligibilityCriteria":82,"healthyVolunteers":78,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":28,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":96,"overallStatus":62,"whyStopped":28,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"St. Louis University","OTHER",[8,17],{"label":9,"type":10,"description":11,"interventionNames":12},"Medrol group","ACTIVE_COMPARATOR","Patients will receive Medrol dose pack, Meloxicam, Hydrocodone\u002FAcetaminophen, and Gabapentin as pain regimen upon discharge from surgery.",[13,14,15,16],"Drug: Meloxicam 15 mg","Drug: Medrol 4 MG Oral Tablet Includes Medrol Dosepak","Drug: Gabapentin 300 mg","Drug: Hydrocodone 5Mg\u002FAcetaminophen 325Mg Tab",{"label":18,"type":10,"description":19,"interventionNames":20},"No Medrol group","Patients will receive Ketorolac, Hydrocodone\u002FAcetaminophen, and Gabapentin as pain regimen upon discharge from surgery.",[15,16,21],"Drug: Ketorolac 10 Mg Oral Tablet",[23,29,33,37,41],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DRUG","Meloxicam 15 mg","PO once\u002Fday for 1 week",[9],null,{"type":24,"name":30,"description":31,"armGroupLabels":32,"otherNames":28},"Medrol 4 MG Oral Tablet Includes Medrol Dosepak","PO 6 day taper",[9],{"type":24,"name":34,"description":35,"armGroupLabels":36,"otherNames":28},"Gabapentin 300 mg","PO every 8 hours for 1 week",[9,18],{"type":24,"name":38,"description":39,"armGroupLabels":40,"otherNames":28},"Hydrocodone 5Mg\u002FAcetaminophen 325Mg Tab","PO 1-2 tabs every 4 hours as needed (total of 28 pills)",[9,18],{"type":24,"name":42,"description":43,"armGroupLabels":44,"otherNames":28},"Ketorolac 10 Mg Oral Tablet","PO every 6 hours for 5 days",[18],[46],{"name":47,"affiliation":5,"role":48},"Scott Kaar, MD","PRINCIPAL_INVESTIGATOR",[50,55],{"name":51,"role":52,"phone":53,"phoneExt":28,"email":54},"Scott Kaar","CONTACT","314-617-3405","scott.kaar@ssmhealth.com",{"name":56,"role":52,"phone":57,"phoneExt":28,"email":58},"Allison Gruender","314-617-3406","allison.gruender@health.slu.edu",[60],{"facility":61,"status":62,"city":63,"state":64,"zip":65,"country":66,"countryCode":67,"cosmosGeoPoint":68,"geoPoint":73,"contacts":28},"Saint Louis University","RECRUITING","St Louis","Missouri","63110","United States","US",{"type":69,"coordinates":70},"Point",[71,72],-90.19789,38.62727,{"lat":72,"lon":71},{"type":48,"investigatorFullName":47,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"Professor, Orthopaedic Surgery","100605127","phase-4-efficacy-of-methylprednisolone-for-pain-control-after-acl-repair-100605127",false,"NCT07158476","Efficacy of Methylprednisolone for Pain Control After ACL Repair","Efficacy of Methylprednisolone for Pain Control After ACL Repair: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patient undergoing ACL repair or ACL reconstruction with tendon autograft\n* Age 13-50 years old\n* Able to provide informed consent or parent\u002Flegal guardian is able for minors\n\nExclusion Criteria:\n\n* Concurrent and significant injury to other bones or organs (Injury Severity Score of 4 or greater)\n* Revision ACL reconstruction\n* Concomitant additional ligament reconstruction or high tibial osteotomy\n* A history of alcohol abuse, substance abuse or chronic opioid use (filled opioid medication ×2 within 6 months of the surgery)\n* A history of renal failure (\\\u003C60 mL\u002Fmin\u002F1.73 m2), liver dysfunction (child class, \\>B), severe heart disease (NYHA Class 4), diabetes, neurological or psychiatric diseases that may affect pain perception, and pre-existing immune suppression.\n* A history or active peptic ulcer disease, gastrointestinal bleeding, or current use of anticoagulation.\n* Patients currently taking oral or injectable glucocorticoids and those who have taken either within 1 month of the procedure.\n* Patients who are currently pregnant.\n* Patients who are unable to undergo the multimodal pain standardized protocol including those with comorbidities or medical allergies precluding the use of corticosteroids, gabapentin, hydrocodone, acetaminophen, ketorolac, and\u002For meloxicam.","ALL","13 Years","50 Years",{"count":87,"type":88},90,"ESTIMATED","INTERVENTIONAL",[91],"PHASE4","Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repair surgery to determine if this results in decreased postoperative pain and opioid use without increasing complications.",[94,95],"ACL Surgery","Pain Management",[97,98,99],"pain","opioids","orthopedic surgery","2025-10-22",{"date":102,"type":103},"2025-10-24","ACTUAL",{"date":105,"type":103},"2025-10-21",{"date":107,"type":88},"2031-09",{"name":5,"class":6},1]