[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641602":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":26,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":26,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":77,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Aristotle University Of Thessaloniki","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Enteral supplementation","EXPERIMENTAL","Enteral supplementation with ARA and DHA (in a 2:1 ratio) in addition to standard care and feeding.",[13],"Dietary Supplement: Enteral supplementation with ARA and DHA (in a 2:1 ratio) in addition to standard care and feeding",{"label":15,"type":16,"description":17,"interventionNames":18},"Routine practice","ACTIVE_COMPARATOR","Routine clinical care and nutritional support",[19],"Other: Standard care and feeding",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Enteral supplementation with ARA and DHA (in a 2:1 ratio) in addition to standard care and feeding","The intervention group will receive enteral supplementation containing arachidonic acid (ARA) and docosahexaenoic acid (DHA) in a 2:1 ratio, in addition to standard care and feeding. Supplementation will begin within the first three days of life and will continue until 36 weeks postmenstrual age.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Standard care and feeding","The control group will receive routine clinical care and nutritional support according to current neonatal unit protocols, without additional ARA\u002FDHA supplementation.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Maria Lithoxopoulou, MD, PhD, MBA, Ass. Prof.","CONTACT","+30 6932883161","mlithoxopoulou@yahoo.com, lithoxopoulou@auth.gr",[38],{"facility":39,"status":40,"city":41,"state":26,"zip":26,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Papageorgiou General Hospital","RECRUITING","Thessaloniki","Greece","GR",{"type":45,"coordinates":46},"Point",[47,48],22.93493,40.64072,{"lat":48,"lon":47},[51,52],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"name":53,"role":54,"phone":26,"phoneExt":26,"email":26},"Maria Lithoxopoulou, Assistant Professor","PRINCIPAL_INVESTIGATOR",{"type":56,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100641602","phase-4-enteral-lipid-supplementation-and-bronchoplumonary-dysplasia-of-premature-infants-100641602",false,"NCT07652684","Enteral Lipid Supplementation and Bronchoplumonary Dysplasia of Premature Infants","Enteral Lipid Supplementation and Bronchoplumonary Dysplasia of Premature Infants: A Randomized Controlled Trial (The PRELUDE Trial)","PRELUDE","Inclusion Criteria:\n\nInfants born at Papageorgiou Hospital in Neonatology Department and NICU of Aristotle University of Thessaloniki with GA equal to or less than 29 weeks are eligible to participate in the study.\n\nExclusion Criteria:\n\nCongenital malformations, chromosomal abnormalities or critical illness with short life expectancy.\n\nStudy participation requires written informed parental consent within 48h after birth.","ALL","24 Weeks","29 Weeks",{"count":69,"type":70},74,"ESTIMATED","INTERVENTIONAL",[73],"PHASE4","The Impact of Omega-3 (DHA - Docosahexaenoic Acid) and Omega-6 (ARA - Arachidonic Acid) Supplementation on the Development of Bronchopulmonary Dysplasia in Extremely and Very Preterm Infants (24-29 weeks of gestational age).",[76],"Bronchopulmonary Dysplasia (BPD)",[78,79,80,81,82,83,84],"BPD","preterm infant","nutrition","ARA","DHA","respiratory support","prematurity","2026-06-11",{"date":87,"type":88},"2026-06-17","ACTUAL",{"date":90,"type":88},"2025-03-04",{"date":92,"type":70},"2027-03-01",{"name":5,"class":6},1]