[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568471":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":42,"responsibleParty":68,"collaborators":26,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":26,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":26,"enrollmentInfo":80,"targetDuration":26,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":26,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Rigshospitalet, Denmark","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Ephedrine group","ACTIVE_COMPARATOR","Ephedrine 0.15 mg\u002Fkg. Dose of ephedrine is based on ideal body weight, calculated as height (cm) minus 105 for women and height (cm) minus 100 for men or actual body weight, whichever is lower.",[13],"Drug: Ephedrine Hydrochloride 30 mg\u002Fml",{"label":15,"type":16,"description":17,"interventionNames":18},"Saline group","PLACEBO_COMPARATOR","Saline 1 ml.",[19],"Drug: Saline (NaCl 0,9 %) (placebo)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Ephedrine Hydrochloride 30 mg\u002Fml","0.15 mg\u002Fkg during induction.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Saline (NaCl 0,9 %) (placebo)","1 ml during induction.",[15],[32],{"name":33,"affiliation":34,"role":35},"Matias Vested","Rigshospitalet, University of Copenhagen","STUDY_CHAIR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Matias Vested, MD, PhD","CONTACT","+45 35 45 75 47","matias.vested@regionh.dk",[43,61],{"facility":44,"status":45,"city":46,"state":26,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Department of Anaesthesiology, Pain and Respiratory Support, Rigshospitalet Glostrup","RECRUITING","Copenhagen","2100","Denmark","DK",{"type":51,"coordinates":52},"Point",[53,54],12.56553,55.67594,{"lat":54,"lon":53},[57],{"name":58,"role":39,"phone":59,"phoneExt":26,"email":60},"Tatiana Nielsen Nielsen, MD","+45 38 63 35 24","tatiana.nielsen.01@regionh.dk",{"facility":62,"status":45,"city":46,"state":26,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":63,"geoPoint":65,"contacts":66},"Department of Anesthesia, Centre of Head and Orthopedics, 6013 Rigshospitalet",{"type":51,"coordinates":64},[53,54],{"lat":54,"lon":53},[67],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},{"type":69,"investigatorFullName":33,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Principal Investigator, Medical Doctor, PhD","100568471","phase-4-ephedrine-for-reducing-onset-time-of-rocurinium-in-elderly-patients-100568471",false,"NCT06681662","Ephedrine for Reducing Onset Time of Rocurinium in Elderly Patients","A Blinded Randomized Study of Ephedrine 0.15 Mg\u002Fkg for Reducing Onset Time of Rocuronium 0.6 Mg\u002Fkg in Elderly Patients (≥ 80 Years)","Inclusion Criteria:\n\n* Age ≥ 80\n* Scheduled for elective operations under general anesthesia with intubation\n* American Society of Anesthesiologists physical status classification (ASA) I to III\n* Informed consent\n* Read and understand Danish\n\nExclusion Criteria:\n\n* Known allergy to rocuronium or ephedrine\n* Neuromuscular disease that may interfere with neuromuscular data\n* Indication for rapid sequence induction\n* Daily use of beta-blocking agents\n* Known cardiac arrythmia (atrial fibrillation, supraventricular or ventricular)","ALL","80 Years",{"count":81,"type":82},80,"ESTIMATED","INTERVENTIONAL",[85],"PHASE4","The aim of this study is to determine the onset time of rocuronium after administration of ephedrine 0.15 mg\u002Fkg in patients with age ≥ 80 years. The hypothesis of this study is that ephedrine 0.15 mg\u002Fkg provides a shorter onset time compared to placebo (saline).",[88],"Neuromuscular Blockade","2025-01-15",{"date":91,"type":92},"2025-01-17","ACTUAL",{"date":94,"type":92},"2025-01-13",{"date":96,"type":82},"2025-12",{"name":33,"class":6},2]