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(Repaglinide, an oral treatment for diabetes mellitus, may be discontinued while taking study treatment with the agreement of the patient's general practitioner, who may start alternate diabetes treatment if considered necessary.)\n* Previous, current or planned use of another investigational drug (tecovirimat) at any point during study participation.\n* The patient's own doctor considers there to be a definite indication for the patient to receive tecovirimat or the local guidelines establish that tecovirimat treatment should be initiated\n* The patient's own doctor considers there to be a definite contraindication to the patient receiving tecovirimat.\n* The patient suffers from hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption.","ALL","18 Years",{"count":243,"type":244},150,"ESTIMATED","INTERVENTIONAL",[247],"PHASE4","The goal of this randomized controlled double-blind clinical trial is to test the drug tecovirimat in patients with mpox (previously known as monkeypox) disease.\n\nThe main questions it aims to answer are:\n\n* Is tecovirimat effective in treating mpox infection.\n* Is tecovirimat safe to treat patients with mpox infection.\n\nParticipants will receive either the drug tecovirimat orally, 600 mg twice per day, or a matching placebo. The outcome of the infection and the side effect experienced will be compared between the two groups.",[250],"Monkeypox",[252,253,254],"tecovirimat","mpox","TPOXX","2025-03-24",{"date":257,"type":258},"2025-03-28","ACTUAL",{"date":260,"type":258},"2024-08-09",{"date":262,"type":244},"2026-08",{"name":219,"class":6},12]