[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554741":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":44,"centralContacts":49,"locations":55,"responsibleParty":67,"collaborators":34,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":34,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":34,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":95,"whyStopped":34,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Riyadh Elm University","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Invisalign Cleaning Crystals","EXPERIMENTAL","Invisalign Cleaning Crystals are used as a cleaning method for orthodontic clear aligners. It includes Sodium Sulfate as an active ingredient.",[13],"Device: Invisalign Cleaning Crystals",{"label":15,"type":10,"description":16,"interventionNames":17},"Fittey Dent Cleaning Tablet","Fittey Dent Cleaning Tablet is used as a cleaning method for orthodontic clear aligners. It includes Sodium Perborate as an active ingredient.",[18],"Device: Fittey Dent Cleaning Tablet",{"label":20,"type":10,"description":21,"interventionNames":22},"Listeren Mouthwash used as cleaning method","Listeren Mouthwash is used as a cleaning method for orthodontic clear aligners. It includes Eucalyptol and Menthol as active ingredients.",[23],"Drug: Listeren Mouthwash",{"label":25,"type":26,"description":27,"interventionNames":28},"Toothbrush and water","ACTIVE_COMPARATOR","Toothbrush and water is used as a cleaning method for orthodontic clear aligners that as recommended by the aligner manufacturer.",[29],"Device: Toothbrush and Water",[31,35,37,41],{"type":32,"name":9,"description":11,"armGroupLabels":33,"otherNames":34},"DEVICE",[9],null,{"type":32,"name":15,"description":16,"armGroupLabels":36,"otherNames":34},[15],{"type":38,"name":39,"description":21,"armGroupLabels":40,"otherNames":34},"DRUG","Listeren Mouthwash",[20],{"type":32,"name":42,"description":27,"armGroupLabels":43,"otherNames":34},"Toothbrush and Water",[25],[45],{"name":46,"affiliation":47,"role":48},"Omar AlKadhi, BDS,MSc","Associated Professor, Riyadh Elm University.","PRINCIPAL_INVESTIGATOR",[50],{"name":51,"role":52,"phone":53,"phoneExt":34,"email":54},"Yara AlSenani, Resident","CONTACT","00966535599141","yara.a.alsenanai2022@student.riyadh.edu.sa",[56],{"facility":5,"status":34,"city":57,"state":34,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":34},"Riyadh","12611","Saudi Arabia","SA",{"type":62,"coordinates":63},"Point",[64,65],46.72185,24.68773,{"lat":65,"lon":64},{"type":48,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"Yara AlSenani","Resident","100554741","phase-4-evaluate-cytotoxicity-leaching-and-structural-conformation-of-clear-aligners-100554741",false,"NCT06503029","Evaluate Cytotoxicity, Leaching, and Structural Conformation of Clear Aligners","Cytotoxicity, Leaching, and Structural Conformation of Invisalign Clear Aligners Subjected to Different Cleaning Methods: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Participants who are on Invisalign Clear aligner treatment.\n* Participants who are 21 years and older and committed to their treatment.\n* Participants with caries-free dentition\n* Participants with no smoking habits\n* Participants are not pregnant females\n\nExclusion Criteria:\n\n* Participants who are on Orthognathic treatment.\n* Participants with Hypodontia.",true,"ALL","21 Years","40 Years",{"count":82,"type":83},84,"ESTIMATED","INTERVENTIONAL",[86],"PHASE4","The aim is to evaluate clear aligners' cytotoxicity, leaching, and structural properties and compare them with four cleaning tools. The null hypothesis is the cleansers have no impact on the properties tested.",[89,90],"Malocclusion","Cytotoxicity",[90,92,93,94],"Leaching","Clear aligner","Orthodontics","NOT_YET_RECRUITING","2024-07-09",{"date":98,"type":99},"2024-07-16","ACTUAL",{"date":101,"type":83},"2024-07-15",{"date":103,"type":83},"2025-03-05",{"name":5,"class":6},1]