[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569963":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":38,"responsibleParty":62,"collaborators":25,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":25,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":25,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":25,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of Southern California","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Long Clomid","EXPERIMENTAL","Clomid with gonadotropins throughout the entire duration of ovarian stimulation without addition of GnRH antagonist",[13],"Drug: Clomiphene Citrate",{"label":15,"type":16,"description":17,"interventionNames":18},"5-day Clomid","ACTIVE_COMPARATOR","Clomid only for 5 days at beginning of ovarian stimulation with gonadotropins, with GnRH antagonist added when the lead follicle reaches \\~14mm.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Clomiphene Citrate","Clomiphene citrate is an estrogen receptor antagonist that leads to pituitary FSH release and prevention of the LH surge.",[15,9],null,[27],{"name":28,"affiliation":29,"role":30},"Richard Paulson","paulsonivf@havingbabies.com","PRINCIPAL_INVESTIGATOR",[32,35],{"name":28,"role":33,"phone":34,"phoneExt":25,"email":29},"CONTACT","323-409-3026",{"name":36,"role":33,"phone":34,"phoneExt":25,"email":37},"Rachel Mandelbaum","mandelbaumivf@havingbabies.com",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"HRC Fertility","RECRUITING","Pasadena","California","91101","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-118.14452,34.14778,{"lat":51,"lon":50},[54,58,60],{"name":55,"role":33,"phone":56,"phoneExt":25,"email":57},"Adriana Wong, MD MPH","866-472-4483","adriana.wong@havingbabies.com",{"name":59,"role":33,"phone":56,"phoneExt":25,"email":29},"Richard Paulson, MD",{"name":55,"role":61,"phone":25,"phoneExt":25,"email":25},"SUB_INVESTIGATOR",{"type":30,"investigatorFullName":28,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Professor","100569963","phase-4-evaluation-of-a-long-versus-short-clomid-protocol-for-controlled-ovarian-stimulation-100569963",false,"NCT06701071","Evaluation of a Long Versus Short Clomid Protocol for Controlled Ovarian Stimulation","Evaluation of a Long Versus Short Clomid Protocol for Controlled Ovarian Stimulation in Patients With Diminished Ovarian Reserve Undergoing In-vitro Fertilization: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Undergoing IVF\n* Must meet POSEIDON criteria based on clinic evaluation\n* Female partner: Antral follicle count of 2 or more and age \\\u003C45 at time of stimulation start\n* Male partner\u002Fsperm source: Cannot be azoospermic\n* Planning freeze-all cycle (regardless of blastocyst or cleavage stage culture) or fresh transfer if randomized to short Clomid group\n* Planning 36-hour trigger window\n\nExclusion Criteria:\n\n* Normal ovarian reserve or good response\n* Allergy or adverse reaction to Clomid\n* Minimal stimulation protocols\n* History of prior premature ovulation","FEMALE","18 Years","45 Years",{"count":75,"type":76},120,"ESTIMATED","INTERVENTIONAL",[79],"PHASE4","The goal of this clinical trial is to evaluate a long Clomid protocol as compared to a 5-day Clomid protocol for ovarian stimulation in patients with diminished ovarian reserve undergoing ovarian stimulation for in-vitro fertilization. The aim of the long Clomid protocol is to intensify stimulation of the ovaries and reduce both cost and injection burden for patients. Participants will be randomized to receive the long Clomid protocol vs. the typical protocol involving Clomid only for 5 days followed by growth hormone-releasing hormone (GnRH) antagonist. The primary outcome the investigators will evaluate will be the number of mature eggs retrieved.",[82],"Infertility, Female","2026-06-01",{"date":85,"type":86},"2026-06-03","ACTUAL",{"date":88,"type":86},"2025-06-01",{"date":90,"type":76},"2028-06",{"name":5,"class":6},1]