[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100352336":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":35,"responsibleParty":63,"collaborators":65,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":25,"eligibilityCriteria":73,"healthyVolunteers":70,"sex":74,"minAge":75,"maxAge":25,"enrollmentInfo":76,"targetDuration":25,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Kettering Health Network","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group; Bupivacaine + opioids","ACTIVE_COMPARATOR","This is the \"standard of care\" arm. This group will receive pre-operative opioid education and \"standard of care\", which consists of an injection of 10cc bupivacaine (plus \\~1cc epinephrine and bicarbonate) into the carpal tunnel and overlying skin pre-operatively, and a post operative prescription for opioids (oxycodone\u002Facetaminophen 5\u002F325). Pain scores and medication usage will be tracked for three days post operatively to assess the validity and efficacy of differing pain management strategies.",[13],"Drug: Differing pain management strategy",{"label":15,"type":16,"description":17,"interventionNames":18},"Experimental Group: Exparel, no opioids","EXPERIMENTAL","This group will receive pre-operative opioid education, Exparel injection (liposomal bupivacaine, with bupivacaine, epinephrine and bicarbonate), and would not receive a prescription for opioids. This injection will be administered as 10cc injected in the operative field, consisting of \\~5cc of Exparel (liposomal bupivacaine), \\~5cc of bupivacaine, and \\~1cc epinephrine. Pain scores and medication usage will be tracked for three days post operatively to assess the validity and efficacy of differing pain management strategies.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Differing pain management strategy","The investigators aim to investigate an alternative (vs \"standard\") pain management strategy for post operative carpal tunnel release. All drugs used are FDA approved for these indications, and no drug itself is being investigated.",[9,15],null,[27],{"name":28,"affiliation":5,"role":29},"Ronald Buczek, DO","PRINCIPAL_INVESTIGATOR",[31],{"name":28,"role":32,"phone":33,"phoneExt":25,"email":34},"CONTACT","937-439-6483","orthostudy2019@gmail.com",[36,55],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Orthopedic Associates of Southwest Ohio","RECRUITING","Dayton","Ohio","45414","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-84.19161,39.75895,{"lat":48,"lon":47},[51,54],{"name":52,"role":32,"phone":33,"phoneExt":25,"email":53},"Laura Peterson","lpeterson@oaswo.com",{"name":28,"role":29,"phone":25,"phoneExt":25,"email":25},{"facility":37,"status":38,"city":39,"state":40,"zip":56,"country":42,"countryCode":43,"cosmosGeoPoint":57,"geoPoint":59,"contacts":60},"45459",{"type":45,"coordinates":58},[47,48],{"lat":48,"lon":47},[61,62],{"name":52,"role":32,"phone":33,"phoneExt":25,"email":25},{"name":28,"role":29,"phone":25,"phoneExt":25,"email":25},{"type":64,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[66],{"name":67,"class":6},"American Society for Surgery of the Hand","100352336","phase-4-exparel-and-education-to-avoid-opioids-after-carpal-tunnel-release-100352336",false,"NCT03867539","Exparel and Education to Avoid Opioids After Carpal Tunnel Release","Inclusion Criteria:\n\n* carpal tunnel syndrome diagnosed either by physical exam or EMG\n* age \\>18.\n\nExclusion Criteria:\n\n* allergy to bupivacaine\n* pre-operative opioid usage within the last six months\n* patients allergic to Percocet or acetaminophen\n* patients taking tricyclic antidepressants (interaction with bupivacaine)\n* vulnerable populations (prisoners or pregnant women)","ALL","18 Years",{"count":77,"type":78},64,"ESTIMATED","INTERVENTIONAL",[81],"PHASE4","This trial seeks to use the long acting local anesthetic Exparel, in conjunction with opioid education, to attempt to avoid any post-operative opioid use following carpal tunnel surgery. This group will be compared with a \"standard\" group that receives non-liposomal bupivacaine, opioid education, and opioids.",[84],"Carpal Tunnel Syndrome",[86,87,88],"hand","exparel","opioid crisis","2026-04-02",{"date":91,"type":92},"2026-04-08","ACTUAL",{"date":94,"type":92},"2019-02-15",{"date":96,"type":78},"2027-12-31",{"name":5,"class":6},2]