[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604339":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":33,"centralContacts":37,"locations":43,"responsibleParty":62,"collaborators":64,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":32,"eligibilityCriteria":72,"healthyVolunteers":69,"sex":73,"minAge":74,"maxAge":32,"enrollmentInfo":75,"targetDuration":32,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":32,"overallStatus":45,"whyStopped":32,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment (extended intervention for tobacco use)","EXPERIMENTAL","Participants receive pharmacist provided one-time tobacco treatment using the five As: Ask, Advise, Assess, Assist and Arrange (5As) model and receives an initial monthly delivery of nicotine replacement therapy (NRT) for 3 months. Participants then receive the extended intervention for tobacco use (EXIT) that consists of: 1) health coach-delivered, weekly-to-monthly wellness-focused telephone coaching for 6 months addressing tobacco use within the context of co-occurring psychiatric and substance-use comorbidities and other life stressors, and 2) an additional session of pharmacist-delivered 5As with monthly delivery of NRT for an additional 6 months. Participants will provide CO samples for biochemical verification of smoking abstinence and complete questionnaires throughout the study.",[13,14],"Drug: Nicotine Replacement Therapy (NRT)","Behavioral: Wellness Coaching",{"label":16,"type":6,"description":17,"interventionNames":18},"Pharm-only","Participants receive pharmacist provided one-time tobacco treatment using the 5As and receive monthly delivery of NRT for 3 months. Participants will provide CO samples for biochemical verification of smoking abstinence and complete questionnaires throughout the study.",[13],[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Nicotine Replacement Therapy (NRT)","NRT will be administered as patch (transdermal), gum, or lozenge",[16,9],[26],"NRT",{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"BEHAVIORAL","Wellness Coaching","Delivered via phone call",[9],null,[34],{"name":35,"affiliation":5,"role":36},"Maya Vijayaraghavan, MD","PRINCIPAL_INVESTIGATOR",[38],{"name":39,"role":40,"phone":41,"phoneExt":32,"email":42},"Jessica Alway","CONTACT","877-827-3222","jessica.alway@ucsf.edu",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","San Francisco","California","94143","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-122.41942,37.77493,{"lat":55,"lon":54},[58,59],{"name":39,"role":40,"phone":41,"phoneExt":32,"email":42},{"name":35,"role":40,"phone":60,"phoneExt":32,"email":61},"628-206-6959","maya.vijayaraghavan@ucsf.edu",{"type":63,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR",[65],{"name":66,"class":6},"Tobacco Related Disease Research Program","100604339","phase-4-extended-intervention-for-tobacco-use-exit-for-people-experiencing-homelessness-100604339",false,"NCT07148232","Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness","Inclusion Criteria:\n\n1. Age 18 years or older\n2. Able to understand study procedures and to comply with them for the entire length of the study.\n3. Ability of individual to understand a written informed consent document, and the willingness to sign it.\n4. Staying at the recruitment site and meeting criteria for homelessness as defined by the Homeless Emergency and Rapid Transition to Housing Act.\n5. Current smoking (smoking at least 5 cigarettes per day (cpd), verified via expired carbon monoxide (CO) \\>= 8 ppm using Micro+pro Smokerlyzer).\n6. Having an intention to quit smoking within the next six months.\n7. English speaking.\n\nExclusion Criteria:\n\n1. Contraindication to any study-related procedure or assessment.\n2. Reasons that preclude the use of nicotine replacement therapy (NRT) (e.g., pregnancy or myocardial infarction in the past two weeks).","ALL","18 Years",{"count":76,"type":77},150,"ESTIMATED","INTERVENTIONAL",[80],"PHASE4","This study is investigating tobacco use and providing tobacco treatment among people experiencing homelessness in California, in San Francisco and Los Angeles.",[83,84,85,86,87],"Tobacco Cessation","Tobacco Abstinence","Tobacco Use","Tobacco Use Cessation","Tobacco Dependence","2025-11-19",{"date":90,"type":91},"2025-11-21","ACTUAL",{"date":93,"type":91},"2025-11-14",{"date":95,"type":77},"2027-06-30",{"name":5,"class":6},1]